MSM Cures and Side Effects
What is MSM?
Alternate names: Methyl Sulfonyl Methane, Dimethyl Sulfone (DMSO2)
MSM (Methyl Sulfonyl Methane) is a compound normally found in foods. It contributes sulfur, which helps with the strength of collagen in the joints.
It is related to DMSO (dimethyl sulfoxide), an alternative treatment for arthritis. Approximately 15% of the DMSO applied to the skin or taken orally results in MSM. MSM may be safer than DMSO, and it does not have the unpleasant side effects of bad breath and body odor.
Food Sources
MSM occurs naturally in cow’s milk, meat, seafood, fruits, and vegetables, although there is no dietary requirement for MSM. MSM is also found in capsule or tablet forms. It is also available in creams and lotions, although MSM is not believed to be absorbed through the skin.
Common Doses
A typical dose of MSM ranges from 250 mg to 2,250 mg daily.
Why Do People Use MSM?
Arthritis – MSM may reduce pain of osteoarthritis.
Fast Relief For Pain
MSM is often combined with glucosamine in arthritis formulas. Preliminary research suggests it may help with osteoarthritis and rheumatoid arthritis.
Interstitial cystitis – MSM has been proposed as a treatment for interstitial cystitis, although further research is needed.
Snoring – one small study found that MSM resulted in “quieter snoring”.
Cancer prevention
Scleroderma
Excess stomach acid
Allergies
Constipation
MSM is naturally found in foods, and is not believed to be toxic. However, its safety record in pregnant and nursing women, children, and people with liver and kidney disease is not known.
Research all published books on MSM
Click here to research books about Vitamins.
Click here to research books about Supplements.
17 YEA
[YEA] 08/24/2008: Kim from Sussex, England writes: "I have taken MSM for years which has helped me with the pain of arthritis. Last year I recommended MSM to an elderly man who drives a tractor who was hunched over when he stood up and seemed to be in pain (though loathe to admit it). I saw him again recently and noticed that he had changed from being bent over to standing fairly straight. I remarked upon this and he said that he was taking MSM every day and that he felt much better."
![]() | ![]() | ![]() | ![]() |
[YEA] 07/07/2008: Tim from Berkeley, CA writes: "I have had seasonal allergies for the past 6-7 years. Earlier this year I read about how MSM can alleviate the symptoms of seasonal allergies, so I decided to give it a try. The allergy season was just starting and I could feel my eyes getting a bit itchy. I started taking 1000 mg of MSM and within 1 hour I was feeling better. It works as well as any OTC allergy medicine with out the negative health effects. As a matter of fact it is supposed to have beneficial health effects. I now take 1000 mg of MSM twice per day and have not had any more symptoms of allergies. I love this stuff."
![]() | ![]() | ![]() | ![]() |
[YEA] 03/22/2008: Robert from Martinez, CA writes: "I have been taking msm 1 gm/day for years as well as family & friends in a combo supplement which includes vit. c & mineral ascorbates.No negative effects reported from anyone."
![]() | ![]() | ![]() | ![]() |
[YEA] 03/05/2008: Joyce from Joelton, Tn writes: "Hi Thomas, Was your question about giving M&M's, MMS, or MSM (methylsulfonealmethane) to your dog? If MSM is yes, it is safe for horses and dogs, and probably for most other animals. Dosage would depend on size of dog, but my recommendation would l/2 tsp for little dogs and progressing upward through medium sized dogs and probably. Probably twice that dosage wouldn't hurt them. After reading that the first doctor that I know of who borrowed from the race horse owners and started treating humans with it, had been taking the race horse dose (close to 1oz) for years to see if had any unwanted side effects from it, and no unwanted side effects to date; but he at the age of 75 (when this wa written) still had a thick head of black hair, and still teaching in a medical school - well, not being one to argue with success- I started at the same dosage. I also have not had any unwanted side effects, but still have the same gray hair with the appearance of scattered black hairs throughout."
03/02/2008: Thamas from East coast australia, nsw replies: "Has anyone tried mms for dogs? If so how much did they give and what were the results?"
![]() | ![]() | ![]() | ![]() |
[YEA] 02/03/2008: Irene from Brisbane, Australia writes: "My husband and I have had wonderful success for over 6 years taking MSM orally and using MSM topically. We each take a teaspoon daily - about 4 grams. It has stopped irritable bowel syndrome and arthritis and been fantastic help in gum problems (gargle).The gel has reduced scars, insect bites, sunburn and creams are anti-ageing. We are passionate about MSM and will always take and apply it. Results have been so dramatic we started a skin care company."
![]() | ![]() | ![]() | ![]() |
[YEA] 01/20/2008: Carrie from Mississauga, Canada writes: "I have been suffering from melasma for about 4 years now. It's on my forehead,and both my cheeks. I have tried everything from bleaches, cosmelan to IPL. Everything is short term. Just as recent as December, 2007, I started taking MSM, vitamin C as well as applying apple cider vinegar on my face. The results are amazing. For the first time in 4 years I can actually say my face has improved and I don't mind going out without makeup. It's only been 6 weeks and I intend on using this remedy to see if it'll get even better. I do hope my experience and information sharing will help someone out there, that has melasma. Good luck!!"
![]() | ![]() | ![]() | ![]() |
[YEA] 12/07/2007: Scott (ksuface@yahoo.com) from Kent, OH writes: "I have been on a quest to cure my asthma for a few years now as I feel that allopathic medicine just makes my breathing worse over time. I recently tried apple cider vinegar and oil pulling with no siginifcant improvement. I have also tried many herbal remedies that I won't even list as they never helped enough for me to give up my inhalers. Let me clarify that my asthma is chronic and I have been on Advair, Singular, a daily nubulizer, Proventil, Albuterol, Primetine, and Asthmanex. On most days I was using a combination of these medications and although they helped to a degree, they never gave me complete relief and if I missed doses I would be close to emergency room wheezing (actually, after starting Advair I went to ER two times and prior to this med - I hadn't been to ER in 15 years). Now it may be that my quest is over as I started MSM last week and I feel as though I had a lung transplant. I can't really put into words how overjoyed I feel and how thankful I am to this website for exposing me to this supplement. I have made it through an entire week without using my inhaler at night and have decreased my inhaler to once a day. I was up to about 10-15 times a day depending on weather and allergens in air!!! I have quit taking singular and have thrown out asthmnex. I will continue to keep my albuterol for emergencies but if MSM continues to work so well - I may not have to use it. I have also found that when I have had difficulty breathing like sledding with daughter the other night - if I wait a few minutes it goes away. Normally, I would reach for inhaler for relief but don't feel that it is as urgent or severe. MSM may not work for others but it seems worth a try because for me it is nothing less than a miracle. Thanks again for this site and happy breathing to all. I will post an update if anything changes."
![]() | ![]() | ![]() | ![]() |
[YEA] 11/25/2007: Joyce from Joelton, Tn writes: "To Sandy: For all those other aches and pains - I swear by MSM - this is what our' bodies convert DMSO into. Remember all the controversy over that one. I have been taking it several years with nothing but good results, however I did read on EC where someone said had bad reaction. You can google to read about it before you try. It is akin to sulphur, but I have no trouble with it despite being unable to take sulfa drugs such as Bactrim."
![]() | ![]() | ![]() | ![]() |
[YEA] 05/26/2007: Ed from Wenatchee, WA writes: "About MSM. Bill Rich on the MSM Cures page wrote about a lotion he put on his scars and the scars were reduced. I would like to know what the ingredients of the "lotion" are. I have a long scar on my right arm I would like to see gone. thanks Ed Davis."
![]() | ![]() | ![]() | ![]() |
[YEA] 05/06/2007: J. Episcopo from Fredericksburg, Virginia (USA) writes: "I have successfully used MSM (the recommended Lignisul type) for many years to allleviate allergy symptoms and pain in my wrists, elbows and knees. It is important for anyone considering a new remedy to read about it beforehand. Some people think that more is better and learn the hard way that each of us has limitations. I like this forum and found it very helpful."
![]() | ![]() | ![]() | ![]() |
[YEA] 04/20/2007: Laura from Ferndale, MD, USA writes: "I have had Psoriatic Arthritis since I was 10 years old, & one of the worst symptoms I've had for 38 yrs now, is daily shooting nerve pains in my extremities. The good news: when I take 1000 mgs of MSM daily, the shooting pains are completely gone. If I miss a few days, they always start up again. Love this site."
![]() | ![]() | ![]() | ![]() |
[YEA] 02/23/2007: JoJean from La Grande, OR writes: "I also take MSM, however, if you read the literature...it tells you not to take it after 2 pm as it may cause sleeplessness. I have never experienced anxiety. I take 4 100 mg caps in the morning and 4 at noon with no problems. It does help my arthritis and my hair and nails grow like crazy."
![]() | ![]() | ![]() | ![]() |
[YEA] 01/14/2007: GG from Houston, TX writes: "MY X PASTOR USED MSM WHEN SHE WAS A SEVERLY ASTHMATIC PERSON/ SHE HAD ASTHMA FOR YEARS FROM BEING ALERGIC TO ALL GRASSES, SHE ENDED UP TO 300 LBS IN THE HOSPITAL ON PREDIZONE AND DIEING CONSTANTLY ON ALBUTEROL ETC, IN THE HOSPITAL A NURSE GRABBED HER AND SAID YOU NEED MSM, SHE STARTED TAKING LIKE 6 PILLS A DAY, LOST ALL THE WEIGHT IT RESTORED ALL HER ORGANS FROM THE DESTRUCTION OF PREDIZONE AND IS NOW COMPLETELY OF ALBUTEROL IT SAVED HER LIFE!! JUST WANTED TO LET YALL KNOW, SHE HAS BEFORE AND AFTER PHOTOS AND NO ONE CAN TELL HER DIFFERENT!"
![]() | ![]() | ![]() | ![]() |
[YEA] 07/23/2006: Charlie from Ft. Smith, AR writes: "I used both Apple Cider Vinegar and MSM to cure a "trigger finger". ' A big knot appeared on the inside of my thumb joint. It was EXTREMELY painful. I couldn't write or do anything with that hand. I didn't realize how important my thumb was. The dr. gave me a cortisone shot in it (ouch) and said if that didn't help, he would have to do surgery and cut the tendons in my thumb to try and relieve the pain. The cortisone shot didn't help. I received a magazine in the mail shortly after this talking about MSM. I decided I had nothing to lose by trying it. After a few weeks of using MSM, ALL the pain went away. (This all happened about 5 years ago). The knot was still there even though the pain was gone (it was a very obvious knot). I then started taking apple cider vinegar tablets and WOW, the knot disappeared!! It is still gone and so is the pain."
![]() | ![]() | ![]() | ![]() |
[YEA] 01/06/2006: Aujah from Huntington Beach, CA writes: "When i was a child my right hip would make a popping sound when i walked. Later on in life, after having a full pain in my hips i found out that my legs are different lengths and was on my way to having arthritis at the age of 21. A friend recommended MSM to help with my nail and hair growth (i can't keep up with how fast my hair and nails grow now). After a week of taking MSM my joint pain was completely gone!!! i was not expecting it at all. Every once in a wile i will forget to take MSM for a few days and my hip pain is back in full swing. I am hooked and it sure is nice to have such strong nail's and healthy long hair."
![]() | ![]() | ![]() | ![]() |
[YEA] Jane from Poulsbo, WA writes: "I have found that taking MSM seems to reduce pain from old injuries and arthritis. Also, MSM seems to add an essential nutrient to the system. It would be good to read one of the books written about this ingredient, nutritional sulphur, since it will answer many questions that people will have. I told a friend about MSM and he started to take it, and found he felt immensely less pain in his back."
![]() | ![]() | ![]() | ![]() |
[YEA] Belle from Los Angeles, CA writes: "I recently started to take MSM to help with neck pain. While it's too soon to tell if it is helping, I can report that it is making my nails grow like crazy!!"
![]() | ![]() | ![]() | ![]() |
9 WARNING! 2 SIDE EFFECTS
[SIDE EFFECTS] 08/10/2008: Denise from Brooklyn, New York writes: "I just started taking 1000mg of msm with 1000 mg of vitamin c and GSE to treat my melasma but today my third day I am feeling kind of strange, anxious, restless and nauseos I dont know much about this supplement and am a little concerned. As much as i want to get rid of the melasma my health is first does anyone know if this passes I already suffer from insomnia and this is making it worse. Would the vitamin c and GSE work on its own?"
[SIDE EFFECTS]08/15/2008: Kim from Macomb, MI replies: "It was good to read it's not just happening to me. I've been taking a liquid form of MSM, glucosamine, & chondroitin for one week STOPPING today. I have been experiencing rapid heart rate and chest tightness/pain. One night I didn't sleep at all. I've taken the gluc/chon before with no issues, so I'm sure it's the MSM. No more. Also of note, I'm allergic to sulfa as many women are, and I just learned that a person allergic to sulfa shouldn't take MSM. It was good to read your feedback. I hope mine helps someone too."
08/17/2008: Maxine from Havana, Arkansas, USA replies: "For all you people who have had a bad reaction to msm. You must start out taking very small amounts and work up to a larger dose. You will have herxhimer syndrome (body getting rid of bad stuff) if you dont. I get mine from vet supply, 5 lbs at a time, msm for horses, it has no fillers 99.9 % pure. Start out with 1/8 tsp, put on back of tongue, because of taste. I have been taking it many years, but had some bad symptoms at first."
EC: Thanks, Maxine. Very good to know...
08/27/2008: Alyssa from Sautee Nacoochee, GA replies: "I agree with Maxine about introducing MSM in small doses. I am on day 9, and for the last 4 days or so I've had a headache.
I felt like I do when I fast - that what I was actually experiencing was a de-tox effect.
After doing more research on MSM, I found that it is also recommended for Candida, which I have suspected for quite some time that I have.
Now, I'm REALLY excited to continue with the MSM in the hopes of not only helping my joint pain, but killing off the candida.
No wonder I've had headaches and I am in NO WAY discouraged from taking MSM. Sounds as if a lot of the warnings are from Herxheimer reaction.
Some info I found on the internet:
"The Herxheimer Reaction - Feeling worse before feeling better
The Herxheimer Reaction is a short-term (from days to a few weeks) detoxification reaction in the body. As the body detoxifies, it is not uncommon to experience flu-like symptoms including headache, joint and muscle pain, body aches, sore throat, general malaise, sweating, chills, nausea or other symptoms.
This is a normal - and even healthy - reaction that indicates that parasites, fungus, viruses, bacteria or other pathogens are being effectively killed off. The biggest problem with the Herxheimer reaction is that people stop taking the supplement or medication that is causing the reaction, and thus discontinue the very treatment that is helping to make them better. Although the experience may not make you feel particularly good, the Herxheimer Reaction is actually a sign that healing is taking place.
What Is The Herxheimer Reaction?
The Herxheimer Reaction is an immune system reaction to the toxins (endotoxins) that are released when large amounts of pathogens are being killed off, and the body does not eliminate the toxins quickly enough. Simply stated, it is a reaction that occurs when the body is detoxifying and the released toxins either exacerbate the symptoms being treated or create their own symptoms. The important thing to note is that worsening symptoms do not indicate failure of the treatment in question; in fact, usually just the opposite.
Symptoms:
The most common ones include:
increased joint or muscle pain
headaches
chills
Heavy perspiration and night sweats
Nausea
Burning micturition
Bone pain
swollen glands
bloating
constipation or diarrhea
fever (usually low grade)
hypotension (low blood pressure)
Itching, hives and rash (sometimes mistaken for an allergic reaction - this must be an MD's call)
heart palpitations, elevated heart rate, orthostatic "
Of course, I'd say that common sense is in order too.
I'll post later to share the results regarding the candida. Already I'm feel I have more energy, and my muscle aches are subsiding."
![]() | ![]() | ![]() | ![]() |
[WARNING!] 07/21/2008: Lisa from SF, CA writes: "MSM sort of a warning... I started taking MSM a few weeks ago, in the hopes of getting rid of, or at least fading, the melasma I have. I started with 2000mg capsules in the a.m. Then increased to 3000mg, and last week to 4000 mg., a combo of tablets and powder (just because I had both, so mixed 'em up). I have not noticed a difference in the melasma, (I am applying topically, too) but have experienced sleeplessness. I already have a problem with insomnia, so this is not good. I noticed the sleeplessness got really bad after increasing to 4000mg., so I've cut down to 3000mg. I really noticed the increase in energy when I started taking the MSM, despite a lack of sleep. About 2 months ago, I began taking SAM-E for mood, and it seems to have helped, but that is also a sulphur compound, so perhaps that with the MSM is too much?"
[WARNING!]10/09/2008: Lisa from SF, CA replies: "I wrote about my MSM experience on 7/21/08. I had to cut down to 2000mg/day, after days of very bad insomnia. I was taking 2x my normal dose of Ambien to sleep, and still was not sleeping well. While taking 4000 mg of MSM, I noticed my hands were incredibly dry, and the veins (in my hands) were much more pronounced than usual. I already drink 1 gal. + of water per day, but while taking the 4000 mg of MSM, I found myself dehydrated even when drinking up to 2 gallons of water a day. The dehydration than led to a bladder infection!
So, taking 2000 mg of MSM for a few months now. Recently began using MSM in a topical vitamin C serum I make, and found insomnia has worsened again! Didn't even occur to me that it could be the topical MSM, but the onset of worsened isomnia corresponds with the addition of MSM to the serum! It's what led me back to this board. Also increased dehydration. Has anybody found topical MSM to have side effects?
BTW: Have not noticed any improvement of melasma (my reason for taking the MSM), nor have I noticed any other benefits. My hair and nails are no stronger or healthier, and I've had no decrease in joint pain. Not sure if I should even continue with the MSM!"
![]() | ![]() | ![]() | ![]() |
[WARNING!] 06/26/2008: Lisa from Rockwell, NC writes: "MSM WARNING: I began having heart palpitations and chest tightness & discomfort after taking MSM for 3 weeks. It did help with hip pain but I had to discontinue it because of side effects. This forum is excellent! I'm glad to know it wasn't just my imagination & that other people have had these side effects."
![]() | ![]() | ![]() | ![]() |
[WARNING!] 11/27/2007: Paula R.Wagner (54th_monarch@cox.net) from Tulsa, OK writes: "re: MSM suppliment, 1000 mg -- I had some bad symptoms similar to Joanna's taking only 1 capsule a day for several days. I'm not allergic to any substances to my knowledge but awoke with difficulty breathing, very sharp pains in my sides, an ache in my back,and my eyes dried out. I'm not real fond of this MSM supplement. Also, my mood was downcast.Watch yourself with this one.."
![]() | ![]() | ![]() | ![]() |
[WARNING!] 11/27/2007: Sherry (Godsanointed777@hotmail.com) from Jacksonville, North Carolina writes: "re: Side Effects of MSM -- I am so greatful to God for this forum. I can totally relate to DL from CA, that posting is almost a total duplicate of what I just recently experienced. I had been having constant pain in my legs and feet for over a year and had, had my fill. I did some research and came across the MSM. I was also diagnosed with asteopenia about the same time, so I decided to try it. Two night ago I had my son take me to the ER, I was having a lot of what's been discribed here concerning the heart beating weird, anxiety(I quess) because I don't know how else to expain how I was feeling, shaollow breathing, heaviness of chest etc. All this had been going on for sometime and I normally could meditate on scriptures and it would go away, this night was different. My jaunt to the ER, showed irregular heatbeat, palputaions to be exact. However, all of my blood work came back normal, showing no previous heart attacks or heart desease. I have been refered for a stress test. I am going to discontinue my use of MSM and see what happens. I will keep you posted as to what happens after I am no longer taking this product. Oh yeah, one of the other effects is headaches. I also started getting headaches that wouldn't go away. I sorta fluffed that off figuring it was a sinus thing, however these aren't sinus area specific. So, I'm thinking this is all related. Time will tell. I am very happy for those folks that this works for. Of course, every bodies matabolism is differnt, so what works for others may not work for someone else. I am very happy for those folks that this works for. Of course, every bodies matabolism is differnt, so what works for others may not work for someone else. Anyone else that may have related info. that would be helpful to my situation please feel free to e-mail me. God Bless"
![]() | ![]() | ![]() | ![]() |
[WARNING!] 10/25/2007: Joanna from New York, New York writes: "I started taking 2 grams of MSM per day for about 9 days (NOW Foods brand in capsule form). As soon as I swallowed a capsule, I became excessively thirsty. I'd even wake up in the middle of the night to drink 2 full glasses of water. I perspired much more (perhaps from all the water I drank), which didn't bother me because I liked sweating more in the sauna. I got pains in my body, especially in my arms and hands - I felt like I was getting arthritis/tendonitis, which was weird because I thought MSM was supposed to help if you have that. My bowel movements increased from 1 per day to 4. At night I'd notice my heart was beating fast. I can usually walk for miles but I got really scared when I found I had trouble walking fast and breathing well on a fairly short walk. I was searching the web for allergic reactions to MSM but couldn't find any. The only other supplement I was taking at that time was 50mg of Ubiquinol (CoQ10). So I stopped taking both. The thirst and breathing/heart problems went away fairly fast, but the pains in my arms lasted a few weeks. Since the time I stopped taking it (probably 1.5 months now), I've been getting sharp pains in my upper abdomen (left and right sides), which have been slowly getting better."
![]() | ![]() | ![]() | ![]() |
[WARNING!] 10/20/2007: Tanya from New Orleans, LA writes: "MSM caused anxiety-- I'm glad to see i'm not the only one. I took some organic MSM and that stuff made me sooooo nervous, rapid heart beat and my nerves felt "fried". OMG this stuff grabbed a hold of me and wouldnt let go. I remembered I took this stuff and stopped. This happened twice. Now i know it was the MSM. I even took some prescription anti anxiety med and the feeling would not go away."
![]() | ![]() | ![]() | ![]() |
[WARNING!] 05/04/2006: DL from BH, CA writes: "I recently bought powdered MSM for a sports knee injury. The pain in my knee literally went away overnight after the first dose on MSM. I got excited and doubled the dose for the next 5 days. At that same time, I started to have anxiety attacks when I lay down to sleep. It felt as though my lungs weren't getting enough oxygen and I started to get paranoid that I was going to stop breathing during the night! My chest felt as though it had an enormous amount of pressure on it. After a few days of this, I realized it had to be the MSM and stopped taking it. My breathing issues went away 48 hours after stopping the MSM. In the future I will take much less of this!"
![]() | ![]() | ![]() | ![]() |
1 2 Next ![]() |
Did
one of these remedies work for you?
Have another suggestion for us?
PLEASE
SEND US YOUR FEEDBACK!




