★★★★★
https://www.sciencedirect.com/science/article/pii/S0753332224007406?via=ihub
Here are some relevant quotes from the study :
' AST ameliorated mechanical and thermal pain in mice with fibromyalgia and mitigated sleep disorders and depressive-like symptoms induced by pain. '
'AST exhibits a significant anti-inflammatory effect, by inhibiting neuronal activation, glial cell activation, and the expression levels of inflammatory factors.'
'AST inhibited the formation of the NLRP3 on the central and peripheral regions.'
It is worth noting that astaxanthin has a very good safety profile as discussed here :
https://pubmed.ncbi.nlm.nih.gov/31788888/
Here is a relevant quote from the review :
' We reviewed 87 human studies, none of which found safety concerns with natural AX supplementation, 35 with doses ≥12 mg/day. '
In a previous article I wrote using astaxanthin to increase endurance, I used 48 mg/day to good effect with no problem. I discussed that here:
https://www.earthclinic.com/supplements/astaxanthin-for-endurance.html
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