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Hi Naomi,
Have you tried applying Povidone iodine(the type typically available at drug stores) as it has shown the ability to penetrate skin. Here are typical products on Amazon for comparison :
If there is inflammation and possibly pain in the area surrounding the seroma, you might try melatonin lotions as I discussed here :
https://www.earthclinic.com/supplements/topical-melatonin-pain-relief-success-stories.html
Good luck and keep us posted!
Art
