★★★★★
It's like clockwork, I run out of my bottle of biotin and within 2 weeks I'll have jaw pain again. It's possible that one of my other supplements depletes biotin. I take magnesium, boron/zinc, b vitamins, fish oils, collagen, mushroom powders, heart/circulation supplements like serrapeptase/nattokinase, and various nootropics so it would be hard to isolate what exactly is depleting the biotin. But I definitely need Biotin regularly. The 300 mcg in the B-complex supplements isn't enough. I take an 8mg pill at least a few times a week.