WARNING!
I have tried EPO several times and the one side effect that has been most prevalent is depression. I take EPO and it feels like my anti-depressant meds aren't working any more. I'm down and feel like I could cry. I stop taking the EPO and my mood levels off and I'm back to my 'normal'. I've only tried it a few times since I thought maybe it was something in the brand. But I have now tried three different brands with the same effect. Other minor issues are bloating, constipation, and heartburn, but these have not been severe.