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1. Check the expiration date on the product, because amino acid supplements go bad within a yr of manufacture date, that is they begin growing bacteria. Keep refrigerated to extend life.
2. You could have a pre-condition of parasites or pathogens which would degrade the gth on contact.
3. Glutathione is an enzyme and thus not very well absorbed in the intestinal tract unless it is aided w/ support nutrients like Vit-C, B-6, digestive enzymes.
4. You may also have improper PH balance in the gut, most likely acidic; and if so will likely also have pancreatic insufficiency and further digestive problems.
As a side-note, if you are trying to boost detox by oral GTH the best way is by LET, otherwise you simply don't get much in your bloodstream. In this event, I recommend supplementing Broccoli Sprouts Extract, which are very well absorbed and very potent phase 1 & 2 detox system agonists, which stay in the body for up to 48 hrs, and also powerful anti-cancer and DNA repairer.
To naturally boost GTH take the mineral Selenium, amino acid NAC, and the hormone Melatonin (before retiring). The humble amino DMG will also complement the previous nutrients for maximum effect (increasing both detox & metabolism). CoQ10 is another nutrient that works great with the above.