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I take K2 during the mid day with main meal. There are different theories on how K2 works. One says it goes to the liver and only is used if needed but don't know for sure. Nattokinase has a 3 to 8 hour window in which it is active. I take it morning and bedtime. So I just take K2 during my evening meal so outside the 8 hour windows.
My plan is to take K2 for 2 or 3 months - sort of like doing a cleansing of calcium from the arteries - then take it every second or third day dor maintenance. I'll experiment.
I would take a strong antioxidant like astaxanthin with your cod liver oil and butter. Fish oil without antioxidant protection can damage your brain.
Here is general guideline for the nattokinase
In regard to what dosage one takes with nattokinase and serrapeptase, it really depends how sick and symptomatic one is. Also age is a factor. As one ages, one can build up a lot of gunk in the arteries. Another factor is the profile of ones disease.
If your under 40 and relatively healthy, ones arteries are generally going to be in decent shape so I don't think one needs it. If one is relatively healthy and over 45, I would say 2000 FU on empty stomach before bed is all you need for preventative measure.
If one has anything related to heart disease and you are symptomatic, it means there are more serious problems going on. So probably a good idea to take higher dose just to be sure. I would dose nattokinase at dosage of 6000 FU 2X per day.
Whether one needs serrapeptase is not clear but it can't hurt and may help. PLus it works a little different than nattokinase. I'd go 80,000 IU three times a day. Take it with nattokinase. In my particular situation, I found I needed it.
You do this for 1 to 3 months. If you think you may have clots that need dissolving, it usually takes 2 to 3 months to take a lot of the clot away. Any symptoms you have should be gone within one month. For maintenance, taking 2000 FU when going to bed and upon wake. It's really ones call to decide whether serrapeptase is right for you and also length of time.
If one has cancer, i'd look into enzyme therapy also.
If one has a chronic illness then besides the aforementioned factors, you have to look at the profile of your disease. If people with your disease are dropping dead from heart disease or show any signs of blood coagulation then I would do a 1-3 month cleansing of your arteries then go on maintenance. So I'd follow what I said about heart disease and adjust it for ones age and other factors. i'd look into enzymes in general and experiment with them.
Everyone's situation can be different so the above is just some framework to operate within. you adjust it accordingly for your risk factors.
There are some rare blood clotting disorders that nattokinase doesn't treat so be careful. nattokinase can replace things like tpa, coumadin etc. It doesn't replace something like heparin. heparin by the way seems like one of the few positive prescription drugs that actually addresses the underlying problems.