★★★★★
In 2014, Xing and his fellow bioresearchers at the University of Minnesota were looking into the reasons why the kava root has both positive and negative effects, which previously were not very well understood. The research team designed a blend of active kava ingredients, hoping to maximize kava's beneficial properties. In clinical trials with mice, this blend prevented the formation of 99% of lung cancer tumors, even in the presence of tobacco carcinogens.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675608/
Formation in Mice: In this breakthrough experiment just published in Cancer Prevention Research Journal, extracts of kava fed to mice at low concentrations of 0.13 to 0.5% of their diet reduced lung tumour multiplicity by a stunning 99%. Of note, this study also showed that kava extract given in food for 30 weeks at a dose of 10 mg/g does not cause hepatotoxicity, which was measured in terms of liver weight, liver pathology, and markers of liver damage (alanine aminotransferase, aspartate aminotransferase, and gamma-glutamyltransferase). The minimum effective dose is actually not yet known since the smallest dose used here was just as effective as the highest dose in suppressing lung cancer. Researchers have also identified the key compounds responsible for kava's anti-cancer activity - known as "Kavalactone-enriched fraction B" (whereas fractions A and C have little anti-cancer effect). Importantly, the B fraction compounds appear to have no liver toxicity, which has been a concern with kava in the past. This may open the path to developing potent, all-natural medicines based on kava for cancer prevention and/or treatment. Note that kava has been served traditionally as a beverage among South Pacific islanders for centuries, and epidemiological evidence has linked kava consumption to an extremely low incidence of certain cancers in these populations.
See Chapter (full text): Cancer – Lung - Kava Blocks 4-(Methylnitrosamino)-1-(3-pyridyl)-1-Butanone–Induced Lung Tumorigenesis in Association with Reducing O6-methylguanine DNA Adduct in A/J Mice or
How to take:
According to Heaven and Herbs, DOSE:40 to 80 drops (3) times per day. Children per protocol: One drop per pound divided into three equal dosages.
