★★★★★
I don't know whether you will be interested in this but I was able to work with a fellow myositis sufferer and his wife in working out how the disease operates. The medical community is focused on the autoimmune reaction however we believe that this is secondary to the real issue. The fellow sufferer has multiple RYR gene defects leading to significantly raised intracellular calcium levels. It took ages but I correlated this with the ACTN3 XX gene variant which responds to high intracellular calcium levels by forcing creatinine kinase from muscle cells. There is much more to this picture however we believe that these are the most significant points.
If you want to know more about our research feel free to contact me though I already have it posted on an obscure natural treatment thread on the myositis TMA forum.
