★★★★★
I have often written about melatonin on Earth Clinic and spoken of its multitude of health benefits for people. One thing that I have often mentioned is that melatonin is protective of the major organs of the body such as the heart, lungs ,kidneys, and liver to name a few.
A new study (May 6, 2023) was just published discussing the use of various antioxidants in people who have sepsis. Sepsis is an extreme uncontrolled response by the body to infection and is life threatening with death as a frequent outcome. Prior to death, multiple organ failure (MOF) can occur and adds significantly to the death rate. It is thought that antioxidants may help improve sepsis outcomes and that is what the following randomized clinical trial sets out to prove or disprove, whether antioxidants can reduce MOF associated with sepsis :
https://www.mdpi.com/2073-4409/12/9/1330
In this study, they used the following four very common antioxidants, NAC, vitamin C, vitamin E, melatonin or no antioxidant in the patient groups with sepsis and MOF to try and determine if these antioxidants would have any benefit in terms of reducing MOF. Of note is that this was a good sized study with 131 patients. Here is an important quote from the study that clearly suggests that antioxidants have potential to significantly reduce MOF :
' In this study, we found that patients with septic shock had a high SOFA ( Sequential Organ Failure Assessment) score on admission to the ICU. They had high PCT and CRP levels, elevated LPO and carbonylation, and decreased TAC. These variables were compensated by the treatment with antioxidants. '
In this study, it was shown that the melatonin group obtained the highest decrease in the SOFA score (75% of the patients). Here is a study quote that shows the response rate to each of the four antioxidants in terms of SOFA score reduction :
' All patients had multiple organ failure (MOF) and low Vit C levels. Vit C therapy decreased CRP, PCT and NO3-/NO2- but increased Vit C levels. The SOFA score decreased with MT in 75%, Vit C 63% and NAC 50% vs. controls 33% (p = 0.0001, p = 0.03 and p = 0.001 respectively). MT diminished lipid peroxidation (LPO) (p = 0.01) and improved total antioxidant capacity (TAC) (p = 0.04). Vit E increased thiol levels (p = 0.02) and tended to decrease LPO (p = 0.06). Selenium levels were decreased in the control group (p = 0.04). '
The following study quote will give a little more perspective in relationship to the dosages used for each antioxidant :
' In addition to the standard therapy, each group of patients received an antioxidant orally or by nasoenteral tube for 5 days. In the NAC group, 600 mg effervescent tablets were administered every 12 h; in the MT group, extended-release capsules of 50 mg in a daily dose were administered; in the Vit C group, 1 g tablets every 6 h and in the Vit E group, capsules α-tocopherol of 400 IU were given every 8 h.'
So the NAC group received 1200 mg total per day in two divided doses given every 12 hours. The melatonin group received one 50 mg extended release capsule per day. The vitamin C group received 4000 mg per day in 4 divided doses of 1000 mg every 6 hours. The vitamin E group received 1200 IU in three divided doses of 400 IU every 8 hours.
So while melatonin reduced the SOFA score in the most patients (75% of patients in melatonin group) the highest percent of these four antioxidants, it did so at the lowest dose given in this study at just 50 mg per day. This illustrates the potency of melatonin when compared to the other three antioxidants and begs the question of what the SOFA score would have looked like had they used a dose of 100 mg or 200 mg of melatonin per day. Even at these higher doses, melatonin would still have the lowest dose compared to the other antioxidants. In the realm of high dose melatonin, 50 mg per day would not be very high. I take 132 mg per day of melatonin myself and have taken high dose melatonin for many years as a preventative and protective agent against many different diseases and health issues.
Another consideration is the fact that vitamin C and melatonin have different methods of action suggesting potential synergy between these two common and inexpensive antioxidants. What would it look like in this study if they had had a sixth leg to the study that combined vitamin C and melatonin? Or what if they used all four antioxidants combined in the patients?
So the point of all of this is to highlight just how good melatonin and antioxidants in general are at protecting the major organs under high oxidative stress conditions that are very damaging to the organs as seen in sepsis. Not just one organ, but multiple organs all at the same time! This study successfully helps to add further corroboration to what I have been saying about the organ protective effects of melatonin and also gives a basic idea of what dose of melatonin (50 mg) is needed in order to obtain these organ protective results. The question remains, what is the most optimal dose to obtain these protective effects of melatonin, but studies are slowly zeroing in on that currently unknown dose. Clearly 50 mg per day of melatonin has very significant benefit in sepsis induced multiple organ failure (MOF), but is it optimal?
Lastly, but also importantly, this study highlights a noninvasive way to effectively deal with MOF as it relates to sepsis, which has clearly shown it can be deadly as discussed in the following link :
As shown in the above link, worldwide, Sepsis affects 18 million people each year and kills 1400 people each day! This study clearly illustrates that sepsis affects 700,000 people in the US alone. Sepsis also has a mortality rate of 30%, but when you add in MOF to the sepsis, that rate jumps upward significantly to 50%!
This next study ( 2022 ) adds a bit more confirmation to the idea that melatonin may have benefit in sepsis associated MOF.
https://www.sciencedirect.com/science/article/pii/S0753332222009453
The above link says that melatonin is associated with a reduced risk of death in sepsis. It further states that evidence suggests that melatonin may help protect organs from sepsis related damage. The study further goes on to list many of the protective effects that melatonin has shown in many areas of the organs of the human body. The study goes on to reach the following conclusion and I make the same conclusion :
'Melatonin is a promising adjuvant for the treatment of sepsis, as it can protect organs by reducing inflammation, oxidation, endoplasmic reticulum stress, and apoptosis as well as protecting mitochondrial function and regulating various other pathways. The safety and minimal side effects of oral melatonin should encourage clinicians to consider melatonin therapy for patients with severe sepsis and septic shock.'
I think these studies and many more should encourage doctors to start using melatonin where it has already shown benefit such as these studies show for sepsis and multiple organ failure. The existing treatments are clearly insufficient for the task at hand as proven by the significant death rate and melatonin has shown significant benefit at dosing that is already known to be relatively safe.
Art
Potato
★★★★★
The Potato Poultice cured my mom's infection in her foot completely in 5 days, prior to starting, the infection had spread up her leg and turned into cellulitus, the potato poultice freshly applied daily cured her completely.
Vitamin C Infusion
★★★★★
Hello All!
I hope you are well.
I have just this minute been advised that someone over there in Australia had been treated for septicemia by many doctors for a long time with no result until a new doctor decided to give the patient an infusion (maybe several?) of Vitamin C and that made all the difference!
Fascinating!
Any profound thoughts on this subject?
Cheers from (the other) Down Under
1.Boil 1 liter of water on the stove
2. Turn off the stove but leave the pot there
3. Add in three to six crushed garlic cloves (three for beginners, then work your way up)
4. Let the water cool down to room temperature by letting it sit for just over an hour
5. Strain the garlic out, using the remaining liquid to fill an enema bag
6. Apply enema and try to hold the concentrate internally for 10-15 minutes to maximize it's effectiveness
Video tutorial – How To Do A Garlic Enema - Anti-Bacterial, Anti-Fungal Amazing Healing Modality
Https://www.youtube.com/watch?v=pn2_oIn9Ftk
Also drink Garlic tea internally. Add ½ tsp turmeric powder to the tea.
This is just a suggestion, I am assuming you have a bacterial infection that has gone sepsis. You can try/build a “zapper” at home according to Dr. Hulda Clark specs in a pinch. Incorporate this with the garlic enema.
According to Dr. Clark's research, the zapper is a simple but very effective electro medicinal device. It is based mainly on the research of Dr. Hulda R. Clark and her son who has published her findings in the book "The Cure of all Diseases" and other subsequent books. Dr. Clark like many other researchers has found that a weak current of pulsed DC current kills parasites in the body. The machine is designed to kill parasites, bacteria, viruses, molds, and even fungi as well as cancer cells and other pathogenic tissue using electrical charges.
When used appropriately, the mechanism eliminates viruses and bacteria within a mere 3 minutes; tapeworms, roundworms, and flukes in 5 minutes; and mites in 7 minutes. Do this in sets of 3. I've seen and done up to 7 sets. Along with using a herbal parasite cleanse. You can build a simple zapper using a fresh 9-volt battery, alligator clips, 2 pieces of copper tubing or wire.
How to build and use a zapper for killing parasites bacteria and viruses – Video https://www.youtube.com/watch?v=k3EewOE2o0w
Watch Bacteria being killed under a microscope while being zapped – Ação do Zapper Concebido pela Dra. Hulda Clark sobre o Paramecium – Video https://www.youtube.com/watch?v=lb9QfDuxVuA
Hulda Clark Documentary Video - The Cure
Https://vimeo.com/8576507
The Cure of all Diseases PDF: Https://archive.org/details/TheBookOfCureForAllDiseases/page/n55/mode/2up
Garlic Tea Enemas
Garlic Tea Enemas
★★★★★
★★★★★
Dr. Paul Marik's protocol is a combination of:
1) Intravenous vitamin C 1.5 grams every 6 hour until ICU discharge
2) Intravenous vitamin B-1( thiamine) 200 mg every 12 hour until ICU discharge
3) Hydrocortisone (low-dose) 50 mg every 6 hour until ICU discharge followed by a taper over 3 days
Here is a YouTube (posted July 1, 2019) about Dr. Marik (the person interviewed in the Mercola article): Sepsis, Coma, Emergency/ICU Patients: DEMAND your doctor for Dr. Marik's VITAMIN C Protocol https://www.youtube.com/watch?v=rm30M0y8yJw
Press the "show more" link under the description. There is information for doctors who want the research behind it.
As for garlic, make sure it is organic. The regular garlic found in supermarkets can be irradiated which destroys the health benefits of the garlic.
Potato
I have used a russet potato to draw out infection.
~Mama to Many~
Potato
Dr. Marik Protocol
★★★★★
There is a Dr. In Norfolk Virginia that has used a natural cure for sepsis in a hospital there. His name is Dr. Paul Marik.
He uses a combination of vitamin c, hydrocortisone and thiamine in an IV.
Even though it has not really been tested that much he has used it even on patients that he expected to die and they survived well. The hospital has adopted the protocol and used it to save, last I heard, 150 people's lives!! There are YouTube videos, check them out! God Bless!
Liposomal Vitamin C
★★★★★
During my recovery I took 2 sachets of Liposomal vitamin c a day. I am diabetic I.e. By all means should be a slow healer and I am in my sixties.
The consultant who specialises in wounds told me he had worked in this field for 30 years and had never seen anyone heal as fast as me. I do not see myself as super woman, I most defiantly put this down to the Liposomal vitamin C.
Oil Pulling
★★★★★
Take about a tablespoon or so of room temp organic coconut oil. place it in your mouth and let it liquify. DO NOT SWALLOW!! Swish the oil very gently in your mouth for as long as you can stand it (15-20 minutes is best) but however long you can do it. Then spit it out into a tissue and into the trash can (cooled oil can eventually clog your drains).
The oil pulls toxins from your system and it's a great preventative for everyone to do every day BEFORE you brush your teeth... just like dry brushing your skin to remove toxins before you take a shower.
If you are very toxic, Oil pull 3-5 times per day brushing teeth with non fluoride tooth paste afterward and dry brush your skin every day. Also eliminate any new toxins from food, water, pollution, etc.
Check into essential oil uses, cleansing herbal teas and nourishing bone broths to help recover.
Oil Pulling
EC: Please see our page on Oil Pulling for more info here.
Oil Pulling
★★★★★
★★★★★
Bread Poultice
Epsom Salt Poultices
★★★★★
Sepsis Remedies
Sepsis Remedies
Sepsis Remedies
I am so sorry about your friend! She is blessed to have you watching out for her!
If you are able to juice beets and get that to her, that would be great! Adding fresh garlic to that mix with a little cayenne pepper would be good.
Turmeric, Burdock root and Dandelion root are all good blood purifiers. If possible, try to get 1 teaspoon of turmeric into your friend 4-5 times day, with plenty of water. (Turmeric can be constipating.) You can mix 1 teaspoon into water or juice or have your friend take 5 capsules each time.
You probably know that most hospital food (at least, in the USA) is not helpful at all to healing. If your friend could stick to just juice (especially fresh) that would be best. Organic carrot is also good to juice.
Hmmm...I just realized you said what can you do to help your friend when she is out of the hospital. Well, all of the above would apply. Perhaps getting these things to her in the hospital is not an option, especially if you do not live nearby.
Please keep us posted.
~Mama to Many~
Sepsis Remedies
★★★★★
Potato
★★★★★
Last summer, I stepped on a scallop shell (on our street) & within a few days was limping and in pain with a 1 inch gash in my heel. A few days later, my husband noticed 2 4-inch long red streaks running up my leg from my heel. I had begun to experience sharp stabbing pains as well.
Since I haven't had an antibiotic in 20 years & see a naturopathic doctor as my primary physician, I wasn't anxious to go to the ER (it was also a weekend) but knew I needed help; sepsis is very real... I found your site & since I had some organic yukon gold potatos called my auntie who confirmed my grandmother used to use crushed potato to draw out boils. I decided to give it a try.
I chopped finely a potato, packed it onto the wound, wrapped w/ Saran wrap, elevated my leg/foot & lay down to focus on healing. My husband photographed my foot at intervals thruout the day. (Well-intentioned neighbors were waiting to drive me to the ER. )
Within hours the red streaks had begun their retreat & the sharp stabbing pains literally "rounded" over. I was very much present w/ this journey. Within 6 hours, the red streaks were gone completely!! I changed the potato 3 - 4 times over the course of the day/night & by morning, the layers of my foot had turned outward. I wish I could put the photos on this site. It was truly remarkable.
One word of caution: Potato juice stains are challenging to remove from fabrics so just make sure you have an old sheet or towel under the site of the potato....!!
I've told SO many people about your site & so many people witnessed first hand the amazing healing property of the simple potato that day... My neighbors thought I was crazy at first! Thank you for providing this forum... It's truly a gift & how we can keep alive these old home remedies. They WORK!
Ted's Remedies
pulses, alcohols for 45 days.. You should daily eat 30 gms of bittergourd and 20 gms of ginger.. you can eat rice and wheat items of food...kumrao99[at]yahoo.co.in
Ted's Remedies
BHT MIGHT help. I do NOT know....Oscar
Ted's Remedies
★★★★★
Posted by Jackie (Knysna) on 11/10/2011:
Ted, please help... my friend literally has hours to live. She has septicemia/blood poisoning and is in a coma. She has suffered lupus for 15 years. Please give your advice urgently.... can I give her DMSO and how much? This is a last effort and I know it it is a long shot. PLEASE HELP.
Get clove oil spray 5% the other 95% is alcohol, or similar. Spray the body with this, legs etc. Give colloidal silver 1 teaspoon every hour. Give hydrogen peroxide 3% one cap to two capful of per liter of water, and give 1/2 glass every hour. After 6th dose most of septicemia will be under control.
You can give any hydrogen peroxide 3% in this dire emergency, such as pharmacy grade. Aspirin is usually good choice also it digests these septicemia.
If fever does not reduce by 3 hours, I will be forced to give 500 mg of aspirin every hour for 4 hours. It works like antibiotics by digestion. The other is lysine every hour for four hours also. These can be given at the same time. So one can do all of it -- h2o2, aspirin, lysine, and clove -- if you want.
Ted
★★★★★
Use heat for that kind of infection, but be careful not to let it get worse. It is serious to have blood poisoning.
Bread Poultice
★★★★★
The way it works is very simple. The bread is very poreous and by dripping water onto the middle of the bread, capillary action moves the water through the bread. Attach that wet spot to an OPEN infection and the water in your body joins the parade along with the poisons from the infection. When the drops are applied they also turn the bread that gets wet into a kind of sealing paste around the wound to ensure that the "cyphon" works properly. If you don't believe me just try this on your body (somewhere discrete).with the bread taped on but exposed to the air. You will give yourself a "hickey".
Live long and thrive! Paul
★★★★★
Marc (Jacksonville, Fl) on 02/04/2009: "possible blood poisoning. I scratched my arm with a piece of metal about a week ago. Now in that area it is swollen and red. I have my tetanus shot, what will bring the swelling down, and heal my arm?"
Hello Marc,
If you haven't gotten started on that swelling/redness by now, run, don't walk to the nearest Dollar Tree or such and get a 2 lb. carton of Epsom salts (magnesium sulfate) and start doing hot epsom salts compresses 4 times a day to take care of it.
Mix it about 1/4 cup per quart of water as hot as you can stand to wring the cloth out without burning your hands.
