The comments below reflect the personal experiences and opinions of readers and do not represent medical advice or the views of this website. The information shared has not been evaluated by the FDA and is not intended to diagnose, treat, or prevent any disease or health condition. Always consult a qualified healthcare professional for medical concerns.
L-Lysine
Posted by judith (USA) on 12/30/2023
★★★★★
Lysine for canker sores works wonders! My son had a mouthful after having his wisdom teeth out and they healed up quickly. Recently I had plantar facitis and found 5 star reviews for lysine and tried it and it worked in 24 hours! Amazing stuff. I don't know what the chemistry behind it is, but I am grateful!
L-Lysine
Posted by Bill (NC) on 04/14/2022
★★★★★
I agree, Lysine is the solution for Canker sores. Take it daily.
L-Lysine
Posted by Buzz (Las Vegas, Nevada) on 12/27/2016
★★★★★
I always take lysine for canker sores. Recommended by my Dr 40 years ago. Also use peroxide. Usually goes away within 5-7 days.
L-Lysine
Posted by Uc Mom916 (Kent, Wa) on 12/24/2016
★★★★★
Canker sores - I started getting them when I was 5 yrs. old. I was eating alot of chocolate. I had a mouth and throat full of canker sores. This progressed as I got older. Early twenties, I would eat hot dogs and bologna....and more canker sores came. I started noticing the connection. I also started doing alot of research on this and many other health related things. What I came across was a book on Amino Acids and how they work and what symptoms you may have if you are depleted. Aha, when you have too much Arginine and not enough Lysine...they will come.
At the tiniest of inklings that I'm getting a canker sore, I take L-Lysine 2 grams (4 - 500mg) capsules on an empty stomach, 3 times a day. I have had a bit of runny stool, but it goes away. The next day, the canker sore has disappeared. I am so grateful for Lysine.
L-Lysine
Posted by Aisling (Galway, Ireland ) on 08/18/2015
★★★★★
Lysine, an amino acid, is brilliant to alleviate mouth ulcers, just use recommend dose on pack, usually about 2 X 1000 mg tablets. You can use them continuously to help prevent ulcers if you are prone, or else just when you get an ulcer. I've tried everything, including soluble steroids but listen works brilliantly. Within two days the ulcer will have virtually gone. Corsodyl mouthwash is also quite good for bringing instant relief.
L-Lysine
Posted by Jmcclain (Little Rock, Ar) on 03/11/2014
★★★★★
I remembered the recommendation for Lysine for canker sores-- after I had a full-blown painful one. I did not want to wait however long it takes for the Lysine to work in my system, so I simply held a Lysine tablet on the sore for as long as I could (about 3 minutes). It immediately stopped stinging and began to heal. A few hours later, I did it again (motivated to hold it longer) and I am pain free now. It still looks terrible but does not hurt. I never dreamed it would work so quickly.
L-Lysine
Posted by Mary G. (Santa Cruz, California, Usa) on 03/25/2012
★★★★★
About 8 years ago my daughter (then in her early 20's and my husband both were plagued with canker sores. A co-worker of mine at the time suggested L lysine, 500 mg tablets. It totally cleared up the canker sores and they didn't need to keep taking it after the sores were gone. They both keep a supply handy to take at the first sign of a recurrence.
L-Lysine
Posted by Mmsg (Somewhere, Europe) on 02/19/2012
★★★★★
Finally, after 5 years of constant struggle with canker sores, I hope I've found the solution, thank G-d! I had taken l-lysine on an off with varying degrees of success untill I was told to take it (with water, of course) ON AN EMPTY STOMACH, away from food. For me, that was the secret, and so far so good, not one new sore! Now I just take one capsule of 500g. once in the morning for maintenance.
L-Lysine
Posted by Bill (Orem, UT) on 05/28/2008
★★★★★
I've had massive dime-sized canker sores for years and had tried just about everything by the time I had finally found this website. I tried the recommended L-Lysine tablets 2 times a day (morning and evening) and have been doing so for about 6 months now. I am happy to say I have finally found the cure for canker sores, trust me, L-Lysine works! I never get canker sores anymore.
L-Lysine
Posted by Carol (Hamburg, NY) on 03/14/2007
★★★★★
For years, my teenage grandchildren suffered through excruciatingly painful episodes of canker sores. After trying & failing with many remedies suggested by their mother & others, including their M.D., they finally tried the old-fashioned home-remedy that their great-grandmother used! L-lysine, a simple, low cost cure. They now are tried & true users of L-lysine, and have almost become heroes with their college friends. The treatment is: Immediately upon the beginning of an out-break, take two 500 mg. tablets. Continue taking one 500 mg. tablet each day until 2 or 3 days past the day the canker sore appears to be healed. "L-lysine is an essential amino acid needed in our diet. It is found in animal protein, such as milk protein. It is recommended that young adults need approximately 23 mg of L-lysine per day per kilogram (10 mg per lb) of body weight. The proteins of cereals; wheat gluten, for example, do not provide enough L-lysine (Columbia University Press Encyclopedia)". Little do the young believe that Grandmother's could be so smart - until they try the "old- fashioned home remedies!
L-Lysine
Posted by Maya (Ft Leavenworth) on 11/19/2005
★★★★★
My daughter and I would get canker scores often, until a friend told me about Lysine. We both take one a day, and if ever one starts to appear, then take 2 pills and the scores are gone. I told a great friend who had very dry lips and the lysine has worked for her as well! Love it! The pain is gone!
L-Lysine
Posted by Thesa (Colorado Springs) on 11/15/2005
★★★★★
My 5 year old daughter came down with a horribly serious case of canker sores. Her mouth had several sores on her tongue, cheek, and gums. Her gums were so red and swollen you could barely see her little teeth. Her breath was absolutely terrible and she barely ate or drank a thing. Finally after a week of different attempts, we had her gargle with 6 drops of tea tree oil in 4 oz. of water three times a day, gave her half an adult dose of L-lysine crushed up into water once a day, gave her a homeopathic every hour and had her drink 16 oz. of water with acidophilus/FOS throughout the day. We kept her completely off of sugar, dairy and meat and mostly she ate cottage cheese and plain yogurt. Within one day she was so much better and finally eating and within 3 days totally better!
L-Lysine
Posted by Lynda (Durham, NH) on 10/20/2005
★★★★★
My nurse practitioner recommended L-Lysine for my debilitating canker sores. They would last for weeks and were so bad that the pain extended to my neck and lymph nodes. I couldn't even eat without excruciating pain. When I feel a canker sore coming on, I take 1 gram 3 times a day and the sore is gone within a day or two.
L-Lysine
Posted by Donnie (Spartanburg, SC)
★★★★★
A supplement called LYSINE helps to heal mouth sores faster, just take a 1-gram capsule 2 or 3 times a day.