I am a 61-year-old woman recently diagnosed with Primary biliary cholangitis with overlapping Hep A and vanishing bile ducts. I don't want to treat with conventional medicine as they are going to give me a high dose of steroids along with other medication I would like some information.,
Cholangitis Natural Remedies
Cholangitis Natural Remedies
Cholangitis Natural Remedies
In studies that I have read, melatonin seems to start to show benefit at 10 mg and more so at 50 mg. I take 132 mg/day as a significant disease preventative and for the multitude of positive health effects that melatonin offers and also to try and offset the natural decline of melatonin production with age that seems to correlate with age related diseases. Dr. Shallenberger suggests 180 mg/day for all of his patients and 360 mg/day in his late stage cancer patients as melatonin is quite useful for cancer among many other health issues. You can also get melatonin from earlier morning and later afternoon sun exposure.
Art
Cholangitis Natural Remedies
Thank you sooo much for your advice. I used to take magnesium citrate and then got scared as I'm not absorbing the supplements I already take plus nutrient dense diet. Now I take magnesium chelate and my last lab test showed within normal limits.
What dose of melatonin do you suggest and brand as I am so numb considering some say to take 3mg some 5 mg or higher. Thankfully, I sleep very well at night as compared to when I worked shift work in intensive care cardiology.
How I wish I heard of earthclinic.com 3 years ago! It's been maddening how "experts" in the best hospital in UK just left me to deteriorate. I'm not bitter, God had a plan for me and part of it has been your advice and the wonderful wise supportive community at earthclinic.
Kindest regards
Cholangitis Natural Remedies
One supplement that may be beneficial is melatonin, but it also has modest blood thinning effects. You may have to increase your vitamin K food intake in order to try and offset this effect of melatonin. Here are a few vitamin K foods :
https://health.clevelandclinic.org/foods-high-in-vitamin-k/
Melatonin has shown the ability to reduce ALP and GGT among other liver enzymes and is also liver protective as discussed here :
https://www.sciencedirect.com/science/article/abs/pii/S0965229920300467
Here is a relevant quote :
' The results showed that melatonin had a significant effect on aspartate aminoteransferase (AST) (WMD = 2.29, [95 %CI: 1.14, 3.43] IU/L, p = <0.001), alkaline phosphatase (ALP) (WMD = −8.40, [95 %CI −11.33, −5.48] IU/L, p < 0.001), and gamma-glutamyltransferase (GGT) (WMD = −33.37, [95 %CI: −37.24, −29.49] IU/L, p= < 0.001). '
I have often said that melatonin is protective of the major organs of the body and the liver is not an exception. The following study show a few of the protective effect of melatonin on the liver :
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412268/
Here is a relevant quote :
' Therefore, the search for a new treatment that could safely and effectively block or reverse liver injuries and diseases remains a priority. Melatonin is a well-known natural antioxidant, and has many bioactivities. There are numerous studies investigating the effects of melatonin on liver injuries and diseases, and melatonin could regulate various molecular pathways, such as inflammation, proliferation, apoptosis, metastasis, and autophagy in different pathophysiological situations. Melatonin could be used for preventing and treating liver injuries and diseases. '
The other supplements you mentioned are also good, but you are trying to avoid multiple blood thinning effects. You may have to talk to your doctor about how high you can safely take your INR level, temporarily in order to get to a healthier state.
Another supplement to consider that appears to have a positive effect on the liver is magnesium in a bioavailable form such as magnesium glycinate or magnesium citrate. The citrate version, if there is constipation involved and the glycinate version if not. You want to be at the RDA for elemental magnesium or a bit more if your doctor will allow it. The following study gives an interesting stat about magnesium and liver disease :
Here is a relevant quote :
' The relationship between magnesium levels and liver disease is intriguing: in many liver diseases, patients are magnesium deficient, while insufficient magnesium levels in turn aggravate these diseases (3, 7-9). In fact, every 100 mg increase in magnesium intake is associated with a 49% decrease in the risk of mortality due to all liver diseases (10). '
That sounds like a very good reason to be magnesium replete!
Art
Cholangitis Natural Remedies
I started TUDCA today ( URSO made me so weak and with a BMI of 17.3, I am needing help. I have the ABCB11 genetic biliary disease which established consultants told me if the GGT and ALP remain over 430, they want to rake out my gall bladder (has a 3 mm polyp) and do another liver biopsy which I don't want. I still juice and doing a gentle parasite, liver and kidney cleanse. If you could sacrifice the time on studies to maintain my LFT'S having the homozygous ABCB11 gene. God bless you as I have had no support these last 3 years.
Cholangitis Natural Remedies
I tried replying twice to thank you and hope you got the messages. I am seriously following your advice. Thank you soooo much
Cholangitis Natural Remedies
Sorry to hear about your gallbladder issues and hope you find solutions soon.
If I was in your position, I would read Dr Hulda Clark's books - they are an excellent in depth resource for the lay person and practitioner as to how to cleanse the liver, gallbladder and parasites. She explains the science behind the protocols and the diseases. I would read the last book she published and a few others if possible (The Cure and Prevention of All Cancers 2007, The Prevention of All Cancers 2004, The Cure for All Diseases 1995 and The Cure For HIV/AIDS 2003). These books are very interesting because they also include many case studies.
Dr Clark stresses that a parasite cleanse is of utmost importance and is started immediately. The liver/gallbladder cleanse is only started afterwards because the parasites first need to be removed from these organs.
As to a practitioner, check out an excellent website, https://www.liverdoctor.com/. Dr Sandra Cabot, from Australia, is an internationally well known holistic liver/biliary specialist. She offers consultations and has helped many difficult cases. And, she addresses and treats liver flukes. She also may be able to recommend excellent holistic practitioners in your area.
I think these two resources may be able to assist you.
Cholangitis Natural Remedies
Any experienced guidance appreciated or if someone can direct me to an experienced naturopath with biliary conditions. Was diagnosed 3 yrs ago, stabilised with silymarin and many other supplements and eat organic clean wholefoods nutrient dense diet. Hepatology consultants at KCH just wait for me to deteriorate more. No cure plus I have a 5 mm neoplasm in my pancreas and a 3 mm gall bladder polyp. Gerson therapy for 7 months failed also chlorine dioxide for 7 weeks failed ( both quadrupled my LFT'S. I wonder if I have old parasites as I worked for 6 yrs 20 yrs ago as a voluntary nurse practitioner in West Africa living in the slums and had a history of chronic malaria for 4 yrs (having had a blocked bile duct) Tried TUDCA once but stopped and do castor oil packs hopefully to keep bile flow moving. Thank you for considering my plea for help as I have wasted money on some holistic practitioners who meant well but just guess.
Cholangitis Natural Remedies
The following may be of interest to you :
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134868/
Here is a relevant study quote from the randomized controlled trial (RCT) :
' TUDCA is safe and as efficacious as UDCA for the treatment of PBC, and may be better to relieve symptoms than UDCA. '
TUDCA is a commonly available supplement.
Also worth mentioning is that NAC may be additive as discussed here :
Here is a relevant quote from the two case reports :
' N-acetylcysteine (NAC), as a mucolytic agent, may fascilitate the drainage in partial obstructions by decreasing the mucous viscosity. We suggest that NAC and ursodeoxycholic acid have markedly positive effects on the clinical course of cholangitis and cholestasis when used together by affecting bile viscosity. Here, we present two cases treated with NAC. NAC capsul therapies at 800 mg/day were administered to two patients with primary sclerosing cholangitis. Clinical and laboratory parameters of patients saw significant improvement.'
Art
Cholangitis Natural Remedies
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