by Art Solbrig June 07, 2022
Disclaimer: Art Solbrig, an independent contributor, offers information and opinions on Earth Clinic, not as a substitute for professional medical prevention, diagnosis, or treatment. Please consult with your physician, pharmacist, or health care provider before taking any home remedies or supplements or following any treatment suggested by Art or by anyone on this site. Only your health care provider, personal physician, or pharmacist can provide you with advice on what is safe and effective for your unique needs or diagnose your particular medical history.
Colon Cancer: An Anecdotal Report
Warning:
I am writing this to make an anecdotal report of a friend who had outstanding results in treating her colon cancer effectively. I am not endorsing what she did; I am only reporting her condition, treatment, and results. Colon Cancer is a severe life-threatening condition, and you should always consult with your oncologist regarding any treatment you are considering using.
Around Thanksgiving 2021, a close friend came to visit and brought his sister with him, who I will call Iris. While we were talking, Iris told me that she had just been diagnosed with colon cancer ("CC") and was very concerned. She told me that they also found lumps in her breasts and were going to schedule further testing to determine the lumps' status.
I told her that I was aware of 15 or so supplements that studies have shown potential to fight colon cancer and might be helpful as adjunctive treatment to her oncologist's treatment plan and asked if she wanted to know about them, and she said yes.
I told her only about five supplements because five supplements are doable, but compliance becomes a problem with 15 or more supplements. She agreed that 15 might be more than she would be able to take, but she felt that she would be able to handle five supplements.
I emphasized to Iris that she would have to get her oncologist's approval and supervision because any of the five supplements could react badly with his treatment plan, which could be very dangerous for her. She said she planned on starting as soon as her doctor approved her five supplements.
I don't see Iris often and mainly only hear about her from my friend, her brother. In February of this year (2022), he told me that she was not able to take two of the supplements because she could not tolerate them, and he also told me that she had not ordered one of the supplements, so that meant she was only taking two of the five supplements.
Recently I attended the funeral of a friend's mother, who had passed away. I ran into Iris at the funeral and we got to talking. She smiled at me and said, thank you! I asked why she was thanking me, and she said that she no longer had colon cancer and the lumps in her breasts were gone.
I asked her what happened, and she said that she had only ended up taking two of the five supplements, and apparently, those two had worked. Iris told me that she went back to the oncologist for the appointment for testing of the lumps in her breast, and the lumps were gone.
They also determined that she no longer had colon cancer. She mentioned to her doctor that she was now having chest pains, and he said it might be heart problems and referred her to a heart specialist. She is currently waiting for that appointment.
Vitamin D and Colloidal Silver Daily Dosages
Iris told me that the two supplements that she did take out of the five were vitamin D and Colloidal Silver ("CS"). I asked her how much she took of each one.
She said that she took 10,000 IU of vitamin D every day and 10 mg of CS every day. This dose of CS is equivalent to a 16-ounce or 500 ml bottle of 20 ppm CS every day.
She told me that she drank a bottle every day for an entire month and then stopped. This is the same dose that I normally use as a maintenance dose in myself after doing one week of a loading dose of 20 mg per day when trying to fight pathogens in my body.
These higher doses are based on the amount of blood in the body, the amount of silver that has proven to kill pathogens, and the amount of silver absorbed through oral intake.
She didn't do a loading dose as I normally do, but she did use the same maintenance dose that I often use.
Studies show that CS has demonstrated the potential to fight Colon Cancer, and I will list several of these below.
I have no way of knowing whether the CS and or vitamin D is the reason for her remission, but she told me she didn't do anything else, and studies clearly show that Colloidal Silver is active against Colon Cancer in testing. Iris said to me that while she had ill effects from two of the five supplements she tried, the vitamin D and CS gave her no problems.
Colloidal Silver for Colon Cancer Studies
Here is a study link showing that CS is active against CC :
https://pubmed.ncbi.nlm.nih.gov/31522088/
Here is a relevant quote from the study. AgNPs is the acronym for colloidal silver nanoparticles.
>>> Notably, AgNPs altered all phenotypes or functions of cells in a dose-dependent manner. Therefore, our research provided a new paradigm for revealing the killing mechanisms of AgNPs against colon cancer cells from single-cell biophysical aspects, which could advance AgNP-based nanotechnology cancer therapy. <<<
Here is another study :
https://pubmed.ncbi.nlm.nih.gov/31407249/
Here is a quote from the study :
>>> The findings indicated that the green fabricated AgNPs have the potential as a promising approach toward the colon cancer therapy. <<<
Another study :
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7250703/
Here is a quote from the study that suggests that the effective dose of CS is doable in humans :
>>> SRB assay expressed biomass-stabilized AgNPs as effective cytotoxic particles against HCT116 colon cancer cells, and the IC50 was measured at 1.7 µg/mL. Annexin V apoptosis assay further confirmed that the AgNPs induce apoptosis in a dose-dependent manner. Experimental evidence manifested that the AgNPs arrest cell cycle and expressed entrapment of a greater number of cells in the Sub-G1 phase, further verifying the anti-cancer abilities of AgNPs. <<<
Another study, this one testing both silver or gold nanoparticles against colon cancer cells, and an important point that this study makes is that CS also uses the generation of reactive oxygen species ("ROS") as one of its many methods of action to fight cancer. Many chemotherapy drugs also use ROS as a method of action to destroy cancer cells, but generally, the drugs create more ROS, which at high levels can also significantly damage normal cells :
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7412267/
Here is a relevant quote from the study :
>>> ' The results of the present study suggest that herbonanoceutics-mediated synthesis opens a new era for cancer therapeutic application, which combines the active ingredients of plant extracts and the benefits of nanosystems. The overall results demonstrated that the biologically synthesized AgNPs have more antiproliferative activity in comparison with PS extract and Au NPs which may be due to induction of apoptosis in the HCT-116 cancer cell line. Moreover, our result confirms that the new adopted synthesis method ensures the dual benefits from phyto ingredients which further enhances the effectiveness of advanced nanomedicine. ' <<<
This next study is interesting because it also shows that CS that has been capped has stronger anti-cancer effects in other forms of cancer such as breast and bone cancer as well as colon cancer. Capped colloidal silver means it has been made using a capping agent like gelatin.
https://www.sciencedirect.com/science/article/pii/S0928493118328297?via=ihub
Here is an important quote from the study :
>>> Capped silver nanoparticles (cAgNPs) showed excellent anticancer against MCF-7, HCT-116, and MG-63 cancer lines as compared to AgNPs. These cAgNPs showed less toxicity towards normal 3T3 skin fibroblast cells. The cAgNPs also showed the excessive release of LDH, which confirms the increase in the apoptosis of the cancer cells by using the IC50 concentration on dose-dependent manner. The DNA analysis showed complete fragmentation of treated cells when compared with a marker on an agarose gel. Hence these cAgNPs could be used as an effective antitumor agent but needs further cytotoxic studies and target drug delivery to avoid the toxicity on normal cells. <<<
Another study shows the anti-cancer potential of CS against CC :
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7569115/
Here is a relevant quote from the study :
>>> MTT assay reveals that AgNPs had shown good anti-cancer activity against HT29 cells with the IC50 value of 150.8 µg/mL. Based on the study findings, it is concluded that AgNPs synthesized using rhizome of Z. officinale and C. longa have potential anti-cancer properties. '<<<
This new study ( April 2022) is important because it goes into very significant detail about multiple methods of action and multiple pathways by which CS fights CC. I do not believe this is a complete list :
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9015850/
Here is an important quote from the study :
>>> The predictive analysis results indicated that the administration of AgNPs causes dysregulation of genes related to cell-cell adhesion, cytoplasm, centriole, and carbon metabolism, which contributes to anti-cancer activity. It was determined that the deregulation of hub genes GAPDH, ENO1, EEF2, and ATP5A1 causes cellular apoptosis and antiproliferative and antimetastatic effects. Finally, hub genes and immune cell infiltration were related, finding a positive correlation between ATP5A1 with CD4+ T and dendritic cells. Similarly, a positive correlation between the ENO1 gene with CD4+ T cells was observed. Alternatively, a negative correlation between GAPDH and NK cells was discovered. These findings are fascinating since the administration of AgNPs impacts these genes and, in turn, the infiltration of cells of the immune system to promote the anti-cancer activity in CRC. <<<
Here is another study where they used different dosages of CS to determine the effectiveness of each dose to fight CC, and they showed that CS dose-dependently was toxic to CC cells while also decreasing cell viability :
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8573457/
Here is a relevant quote from the study :
>>> Silibinin assisted silver nano-particles had a spherical shape with an average size of 10 to 80 nm. SSNPs treatments induced dose-dependent cytotoxicity with a concomitant decrease in the cell viability in human colorectal cancer cell line. SSNPs treatment induced p53 protein expression and this could be the possible reason behind the apoptotic changes observed in this study. Thus, SSNPs is a potential therapeutic candidate for in vivo evaluation in the fight against colon cancer. <<<
And another study which is interesting because it shows that in rats that were chemically treated to induce CC, CS returned the rats back to normalcy :
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8858244/
Here is a quote from the study :
>>> M. oleifera nano-extract restored levels of the hematological and biochemical measurements in addition to levels of tumor and inflammatory markers to normalcy in both of nano-extract simult- and post-treated groups. Also, it minimized severity of the histopathological alterations in the simult-treated group and prevented it completely in the post-treated group.
The nano-extract prevented the qualitative and quantitative alterations in the different electrophoretic patterns in addition to restoring levels of the gene expressions to normalcy in both of simult- and post-treated groups. <<<
The following study is significant because it clearly demonstrates that CS is synergistic with 5 Fluorouracil, one of the most commonly used chemotherapy drugs :
https://pubmed.ncbi.nlm.nih.gov/34546492/
Here is a relevant quote from the study :
>>> In this study, it has been shown in vitro that the use of successfully biosynthesized Vv-AgNPs in combination with 5-FU exhibits synergistic cytotoxic, antiproliferative, apoptotic, and oxidative effects against HT-29 cell line. <<<
One last study and this is a very important one because it reveals that the growth inhibition effects of CS is 34.5 times higher than chemotherapy agent Carboplatin and it also clearly shows the low cytotoxicity of CS to normal cells and tissue at cancer toxic doses :
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8308985/
Here is an important quote from the study :
>>> In summary, the results obtained in this work show that a high amount of PVP used as a coating agent to obtain AgNP formulations, independently of polymer length, generates a wide therapeutic window for selective cytotoxic agents to BALB/c mice compared to the first-line chemotherapeutic agent, carboplatin. <<<
It should be noted that PVP is also a capping agent like gelatin is a capping agent.
Conclusion
These studies and many many more studies illustrate that Colloidal Silver is a potent anti-cancer agent and not just for Colon Cancer.
My impression based on these studies is that it has a better safety profile than most cancer drugs at the dosing level needed to fight cancer. Given that the current cancer treatment standards have been in place for many decades and come with some serious side effects that include death, the time is long overdue to start looking at options such as CS by the medical and scientific communities in actual people with cancer.
The safety profile of CS is already known. People around the world are using CS for many different purposes, and Iris is a perfect example of how CS was employed to extremely good benefit by her.
I can't say that this will work for everyone with colon cancer, but the studies show it is effective in multiple tested colon cancer cell lines at dosing levels that are doable in humans. I have been using these higher dosing levels of CS such as Iris used and have not had problems with it. On the contrary, it has worked well, and I have used it with no apparent side effects. How much more proof is needed to make CS a mainstream treatment in many forms of cancer?
If Iris contacts me again with any updates, I will post them.
Art
Where to Buy Colloidal Silver
We are pleased to announce that since the fall of 2021, Earth Clinic manufactures and sells 20ppm Colloidal Silver on Amazon (available with Prime Shipping) and the Earth Clinic Shop. We plan on offering quarts of concentrated 320ppm colloidal silver this fall (2022) to make it cost-effective for high-dose colloidal silver protocols like the one mentioned above by Art.