Apparently, I am very allergic to ALA, I used it for about 3 days, I ended up with a rash on my legs below the knees and my legs were so swollen. I have never been so swollen before. My ankles and legs were extremely swollen. I didn't take it again. I took some Benadryl before bed and my legs are definitely less swollen and the skin seems a touch loose now. Be very careful taking ALA.