Posted by Art (California) on 04/16/2025 2451 posts
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This new (March, 2025) study suggests that melatonin can be useful for helping to heal diabetic wounds :
https://www.sciencedirect.com/science/article/abs/pii/S0040816625001648?via=ihub
Here are relevant quotes from the study :
Highlights
- HG inhibits the AMPK/SIRT1 pathway in endothelial cells.
- Mel activates the AMPK/SIRT1 pathway.
- Mel upregulates HIF-1α expression by activating the AMPK/SIRT1 pathway.
- Mel improves endothelial cell angiogenesis and mitochondrial function via AMPK/SIRT1/HIF-1α pathway to promote wound healing.
The study lays a theoretical foundation for a deeper understanding of the mechanism of Mel to improve diabetic wound healing.
Melatonin Gel may be a potential way to apply melatonin for this purpose. Directions how to make melatonin gel here :
https://www.earthclinic.com/supplements/melatonin-gel.html
Art
