★★★★★
Large, XL, and giant breeds, tolerate enemas well, and provided you use common sense (never use otc phosphate enemas), it is perfectly safe on these dogs.
Glycerin and Water Enema
★★★★★
My 105lb (intact) kuvasz bitch has problems once or twice a month during the summer. I get a 2qt enema bag, add 6-8oz of liquid glycerin and fill with warm water. Insert the hose a bit, and let it flow for a minute then slowly push the hose deeper. The further in you can get it with gentle pressure, the better. Works ever time, usually before she can finish the bag.