My dog was prescribed Ketoconazole and cefpodoxime for an ear Infection. 2 weeks later he passed away. I brought it up to the vet and he said that liver failure is a rare side effect. I asked when he prescribed the medication what side effects there were. He only said vomiting and diarrhea. If he would of told me liver failure it's possible that I would have asked for an alternative medication. I am so sorry I ever gave my dog that medication without researching it myself. Don't trust your vet or the drug companies. Do your homework. I learned the hard way.