But I, and a friend I turned-on to it, both had synovial knuckle "blow outs" and subsequent cysts / bone-spurs while using it. This seems odd, since Serrapeptase is widely touted for join problems, but my friend recalled reading others online confirming this nasty side-effect.
I later learned from a hand specialist that it is the joint scar tissue that keeps the joints sealed and prevents cysts from returning. Seeing how Serrapeptase is also said to digest internal scarring, this is likely how it is bad for those with this joint condition. I wish Serapeptase was still available as a nasal spray formula so I could localize it's positive effects.