The Extensive Health Benefits of Methylene Blue

Diluting Methylene Blue Tips

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Posted by Bill (Philippines) on 06/15/2023
★★★★★

Editor's Choice

I've been experimenting with Methylene Blue(MB) for many years and I thought it might be useful to clear up some of the unfortunate myths that have arisen concerning MB usage.So this post should hopefully help to clarify many apparently confusing aspects when someone supplements MB for the first time for whatever reason.

First, because there seems to be so much dosage confusion about MB percentage strength and number of drops used, I'm going to use a completely different quantitative method that determines how many milligrams or how many drops to supplement MB with water. There has been much of confusion over this.

But first some information that I have found to be extremely useful in helping to more fully understand the effective dosage amounts of MB needed for particular ailments :

1 drop of 1% Methylene Blue contains 0.5 mgs of MB.

1 drop of 0.1% Methylene Blue contains 0.05 mgs of MB

1 drop pf 2.33% Methylene Blue(Aquarium version ) contains 1 mg(approx.)

A half teaspoon of MB is 40 drops.

A full teaspoon of MB is 80 drops.

So armed with the above helpful definitions, I will now only describe MB dosages in milligram amounts only. Doing it this way eliminates all the confusion(and myths) of how you should use 0.1% or 1% or 2.33% MB. After all, it's the dose of MB powder in water that you supplement that is all-important -- not the percentage of MB in your dropper bottle. Right?

Ted from Bangkok has also maintained in his MB posts that supplementing the cheaper aquarium version of Methylene Blue is certainly good enough and pure enough for supplementing in humans. But if that last statement makes some readers balk in fear of "heavy metal impurites" then it's perhaps also useful to appreciate that fish live and breath in water and humans breath air. But water is a much more dense medium than air. And that means that fish are much more sensitive to poisons, heavy metals etc in their water than humans are. So if the aquarium version of MB is good enough for the more sensitive fish then it should certainly follow that aquarium MB is pure enough for us humans as well. And that's also why I've been using the aquarium version of MB, without any problems whatsoever, for over 10 years now.

Other things to remember about MB is that low MB dosages will be good enough to help give you energy and to help MB act as both an antioxidant and antimicrobial for the brain, thus helping to increase and maintain mental cognition as well as helping to prevent dementia(Alzheimer's Disease, Parkinson's Disease etc). However, much larger doses of MB will be required to kill viruses or bacteria, cure malaria, kill fungus, kill parasites, treat Methemoglobinemia, help remove blood clots etc.

But what do I mean when I say take a low dose of MB in water? -- And here is where all the confusion happens. I've read that for some people 2 drops of 1% MB(which is equivalent to 1 mg MB powder on water) is enough to fully energize them. I've also read where other people need to take as much as 16 mgs or even 100 mgs of MB(which is still a low dose for MB) to get energized. The point that I'm making here is that you will normally always have to find your own MB dose that works for you personally.

My own dose, which suits me for getting more energy and obtaining the cognitive benefits from using MB, is based on Dr Golwalkar's method that he has been using over the years to treat and cure both tuberculosis and COVID-19. He uses a teaspoon of 0.1% Methylene Blue for nebulizing(which is equivalent to 4 mgs MB powder in water) and he also recommends taking a half teaspoon of 0.1% MB orally as a sub-lingual dose(which is equivalent to taking 2 mgs MB powder in water).

My own everyday MB dose is slightly different to Dr Golwalkar's sub-lingual dose. I just add half a tablespoon of water to a small empty glass and then add 4 drops of 2.33% Methylene blue(which is equivalent to taking approximately 4 mgs of MB powder) and supplement that twice a day. But I have also taken the equivalent of more that 25 mg MB powder per day without a problem. I would also recommend using Dr Golwalker's recommendation of using 5 mls or 1 teaspoon of 0.1% MB(which is equivalent to 4 mgs MB powder in water) in a nebulizer two or three times a day when infected with COVID-19.

Some more MB facts for you. When you supplement Methylene Blue then between 75% and 80% of the MB taken orally is directly and quickly absorbed into the blood. Methylene Blue has a half-life in the human body of about 6 hours. That means that half the amount of MB that you supplemented will still be in your body after 6 hours. It's for reason of this persistence of MB in the body that I would at least advise that for low dose MB you should at least take one day off a week to reset your system and get rid of all the MB in your body.

I've also found an easy way of converting Methylene Blue from its blue oxidant form to its colorless reduced form. I will, for instance, add my 4 drops of Methylene Blue to a little water in a glass for sublingual supplementation. Then I would add a very small amount -- a tiny amount!! -- of Ascorbic Acid to the MB and walk outside and let the sunlight quickly convert the blue oxidant form of MB to it's colorless reduced form and just take it like that without giving me a blue mouth. I've also used the reduced or colorless MB form on skin problems without any blue coloring occurring. It works well and MB is also rapidly and easily absorbed into the skin.

Replied by Thomas
(Germany)
12/07/2023

Hi. What does mgs stand for? Never seen that weight unit before.

EC: mgs - milligrams

Replied by Bobby
(UK)
03/06/2024
1 posts

Thank you for your detailed information. I have been taking it daily with one day off for the past month. For how long should I continue to take it?

Bill
(Philippines)
03/06/2024

Hi Bobby,

Methylene Blue(MB) has been used as a blue dye and as a standard treatment for malaria for over 120 years. During the Vietnam war MB powder was used by the spoonful over extended periods to help cure soldiers with malaria. For these reasons I regard MB as being quite safe to use over long periods of time.

But if you are concerned about continual use of MB, you could perhaps just use MB for 5 days a week with two days off. Or you could just take a week off after using it every month.

It's also important to ask why you are taking MB. I take MB for preventative reasons -- to aid my immune system against any unwanted, invading viruses and I also take it to help supply more oxygen to my brain to help protect my cognitive abilities.

For myself, I tend to just alternate using low dose MB with using BHT or Butylated Hydroxytoluene which also kills viruses and which is a useful anti-oxidant that acts to quench damaging free radical activity in the brain.

I'm currently considering using an MB + DMSO mix transdermally. Such a mixture could perhaps be used as an ant-viral, anti-fungal, anti-bacterial, anti-oxidant for anti-aging and as an anti-cancer treatment as well. More on that later.

Florecita
(USA)
03/07/2024

Great ideas Bill. I wonder if DMSO and MB topically would remove moles from the skin. Please do post again any results from topical application.

Brent
(Australia)
05/28/2024

Just came across your post as I am about to start using MB for general health reasons. You mentioned moles to remove on skin I have heard that castor oil on its own or some people mix cayenne pepper with it could do the job on moles. Perhaps worth looking into out if you haven't done so already?

Bart
(Columbus, Mississippi)
10/28/2024

Put Apple Cider Vinegar on a cotton ball and hold for 15 minutes per day for 7 days. The mole will turn black a fall off. Works on any issues on your scalp.

Replied by Dee
(Florida)
07/18/2024
★★★★★

I have done my research on MB. I found 2 methods. I just started taking the liquid Methylene Blue with the Ascorbic Acid in Water. I doing the 6 days on and 7th day off method.

2 Methods

How do I mix the methylene blue solution.
The methylene Blue solution I received from Valboren Labs in Florida is in a concentrated liquid form. This should be mixed with distilled or deionized water using the recommended dosing. Dosages between 0.5 milligram per kilogram of bodyweight to 4 mg per kg. As mentioned, methylene blue is a hormetic, so low dosages have the opposite effect of high dosages. Adding 1/16th teaspoon of Ascorbic Acid to the prepared solution will facilitate better absorption and reduce the blue staining potential. After the Ascorbic Acid is added to the solution let it sit for a minimum of 3 hours before taking. With methylene blue less is more. Higher doses are not as effective a low doses (hormetic response). Dosage recommendation varies; Dr. John Lieurance suggests 0.5-1mg/kg of body weigh, t 2 to 4 days a week, with 20 to 60mg daily being therapeutic for many. Do it slowly 2 or 3 drops to start 3 times a week, and work you way up .
or

Method #2

1-2 drops am in distilled water with 1/16 tsp. of Ascordic acid first 2 days.
Increase dose on third day by 2 drops for 2 days, Continue increasing
dosage by 1 drop every 2 days, until you reach 22 drop or more. Take 6 days
in a row and 7th day off. Note: Do not take Co10 with it.

Bill
(Philippines)
07/19/2024

I prefer to take Methylene Blue(MB) according to the recommendations of Dr Deepak Golwalkar, a well known pulmonologist(lung specialist) in India. He has successfully used MB to help cure many people with tuberculosis, pneumonia and COVID-19. Dr Golwalker uses two simple protocols for COVID-19. See below.

Since I prefer talking in milligram amounts rather than drops and percentages of MB please bear the following in mind because it will, hopefully, greatly simplify your own understanding of drop dosages wrt conversions in % strengths.

0.1% Methylene Blue solution contains 0.05mg MB powder per drop.

1% Methylene Blue solution contains 0.5mg MB powder per drop.

2% Methylene Blue solution contains 1.0mg MB powder per drop.

I currently regularly use Dr Golwalkar's sub-lingual MB protocol which consists of taking approximately 5 drops of 1% MB which is approximately equal to 2.5mgs MB. This is held under the tongue for at least 30 seconds and then swallowed with a little more water so that it can be directly absorbed into the blood from the stomach. And this will give you a blue tongue.

You can also use Dr Golwalkers nebulizer protocol which consists of adding 10 drops of 1%(or one teaspoon of 0.1% MB) to the water in the liquid reservoir in the nebulizer. Dr Golwalker also states that all he took in the morning before going to the hospital was MB under the tongue as described. He would always walk around the COVID-19 wards of his hospital tending his many patients without a mask. He never caught COVID-19 and the hospital he worked in never lost a patient to COVID-19 and all his patients made a FULL recovery with no LONG COVID symptoms.

I am currently using the simple sub-lingual protocol once a day(in the morning) at the moment. I find using the sub-lingual protocol on its own is a great energizer and protector at the same time. And there's really no need to use Dr Golwalker's nebulizer protocol until I'm infected with COVID-19, pneumonia or tuberculosis.

Click this link to see a previous EC post I wrote fully describing the many benefits of using MB.

Anxiety, Panic Attacks, Intestinal Cysts

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Posted by Bennie (San Diego, California) on 05/18/2013
★★★★★

UPDATE; Four months of Methylene Blue.

It has no effect on chronic fatigue - doesn't give me any energy; also doesn't keep me up at night if I take it right before bed.

There are two areas where it seems to have worked magic: Cysts and Anxiety; as well as other benefits for insomnia and problem solving.

It did clear up my long term liver/kidney/diaphram/intestinal cysts, and for that, I am very grateful. I stopped taking it for about a week, and the pain radiating from what used to be the most painful cyst began to return, so I am sure this is what fixed them, although I have no idea why it came back and whether to continue taking MB indefinitely.

Anxiety: There's something about MB that fixes my generalized anxiety. It's fairly miraculous in that regard. I did not take it for anxiety, but I notice an improvement (almost total resolution) when I take it. As a result, don't need xanax. Again not sure whether it is safe to take indefinitely for anxiety.

Along with the reduced anxiety, it helps me to focus more on problem solving. Not a complete resolution but a definite improvement. I have chronic fatigue related brain fog, and it definitely gives a boost in that department so I can see why it is being used successfully in Alzheimer's patients.

I think I am sleeping better -- deeper sleep, not getting up so much in the middle of the night, because of the MB, which is huge because I've lived through 25 years of insomnia. Used to take RX sleeping pills of various kinds (4-5 days per week) but not taking them anymore.

When I first started the MB in Feb 2013, I experienced significant tingling in my head (felt like brain buzzing). I was taking several milligrams of melatonin per night, and drinking coffee during the day. Both of those were a problem while taking MB but now, after a few months, I am able to drink a regular cup of coffee now and then with no adverse reactions. I also take a much lower dose (1. 5 mg) melatonin with no side effects. For some reason, tea creates no problems.

MB had no effect on yeast/candida, herpes related virus, or fungal infections.

Other than occassional "brain buzzing", I think MB may have a negative effect on vision (blurrier, esp at higher doses). It MAY have a positive effect on acne but I've been taking a skin/nail/hair formula as well and think it is because of that that my acne has improved.

I am taking 3-5 drops of 0.1% per day.

Perhaps E.C cross post this to Anxiety/panic attacks; and intestinal cysts.
Benni

EC: Bennie's latest update has been cross posted from her thread in the Q&A section on the Methylene Blue page here: https://www.earthclinic.com/remedies/methylene-blue_questions.html#Question_4567.

Replied by Joy
(Battleground, Wash)
05/18/2013

So glad this is helping relieve some of your suffering. Curious about what intestinal cysts are. Did you get a medical picture of them? Love, JOY

Replied by Stanster
(Wilmington, Nc)
06/28/2013

I had tried methylene blue for my brain fog, lack of energy and achy joints, etc. I've been told I have Fibromyalga or Chronic fatigue. I didn't get any great results.

After further study I feel I have Lyme's and overgrowth of those little critters: Borealis bacteria. I urge you to read (google) all you can about Dr. Lee Cowden's protocol. He is doing medical studies using certain herbs and detoxifiers to kill off these bacterial invaders. This is probably the root cause of your problems. This info has changed my life, hope this helps anyone suffering from strange symptoms the medical doctors can't figure out.

j
(Southeast Georgia, US)
04/12/2023

RE: "Lyme" disease & the bacteria that cause it, it was recently discovered that stevia tea (whole leaf only) will eradicate it. Saw it on Dr. Berg's Youtube channel earlier this year.

Best wishes,

Replied by Lena
(New York)
10/23/2016

5 drops? ...I am taking 40 drops of Methylene Blue and do not see much of an improvement, but I am taking it only for 3 weeks so far.

Pam
(Australia)
08/24/2021

I just read somewhere that too much of MB has the opposite effect. I have also cut and pasted from a nootropics page what happens with co q 10 ...

"Methylene Blue donates electrons in the electron transport chain in your mitochondria. So experienced neurohackers suggest avoiding CoQ-10 or idebenone when using MB because it seems to make Methylene Blue much less effective."

Replied by Brass Player
(Sw Usa)
01/12/2017

I also thought I had Lyme disease. It turned out that I had an ongoing toxic mold exposure, that nearly killed me before I found out what it was (and not from a doctor) and got out of my house that had a hidden water leak. Lyme and CIRS (toxic mold illness) have extremely similar symptoms, and common mis-diagnoses are CFS, Fibromyalgia, and any other "syndrome" disease.

Anyone whose doctor says "it must be a virus" yet it never goes away, should go read survivingmold site. Water damaged buildings are common but the vast majority of physicians are not cognizant that 24% of the population has a genetic haplotype that is susceptible to the toxins. So only 1/4 of the people in a water damaged building will be extremely ill, and the other 3/4 either not ill or only with niggling minor illnesses. Well worth a look for the CFS/Fibro people. If I hadn't found out it was mold, I'd be dead.

Dee
(Florida)
08/08/2022

Lufenuron clears up morgellons, because it kills candida and fungus infections. It also eliminates fleas in dogs and cats, because it breaks down the chitin which occurs in both insect and fungus as their protective shells!

Replied by WRE
(Massachusetts)
05/25/2022

IODINE!!!

Lou
(SF Bay Area)
03/22/2023

Iodine what??

EC: Probably iodine supplementation for cysts.

Kevin
(NY)
06/03/2024

Both forms

Replied by kristen
(arkansas)
12/27/2023

What is the application for cysts? Topical? internal?

What type of cysts? sub-dermal fatty cysts?

Leslie
(UT)
04/15/2024

Hi, I'm very interested in an application for sub dermal lipomas - is MB effective in reducing or eliminating them?

Be Careful - It Stains Surfaces!

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Posted by Lis (Ny, Ny, Usa) on 10/13/2010
★★★★★

When diluting this, set up protective material underneath. MB stains! I rubbed vitamin C and water paste in the measuring glass and spills on the sink and counter and on my hands to get it out. If only I had a chemistry background to do a more pro job diluting it ;p

Benign Skin Lesions

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Posted by Lisa (Hawaii) on 08/17/2017
★★★★★

METHYLENE BLUE, I have been using MB topically on benign skin lesions, the doctor had been freezing them off, but they eventually come back and the freezing is painful. So I just applied the 2.3% (fish stuff) directly on the spots. They take up the dye, and dry up, I reapplied it to the larger spots a few times, the small spots just healed up very fast. skin is looking great, no pain.

Broad Benefits

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Posted by Terry Jacks (Texas) on 12/16/2022
★★★★★

Editor's Choice

It's not working very well for you? Based on your statement about 3-5 drops of 1%, I can see why. You should consider taking AT LEAST 15mg per day, which is 30 drops of 1% strength. The typical recommended dose is 40 to 360mg. I think 360 is a bit high, but 40 is fine. I take 30 to 40mg per day with great results for energy, attitude, skin condition, muscle strength gains, diabetic neuropathy, calmness, sleep quality, blood glucose control, eyesight, circulation and lasting energy during hard work.

Replied by Maria
(Canada)
05/22/2023

Do you take this in the mornings or night? Daily? Every day of the year? Take breaks from it?

Replied by Terry Jacks
(Texas)
07/20/2023
★★★★★

MANY Health Problems are caused by consuming SEED OILS. Seed oils are called "vegetable oils". All seed oils have a devastating effect on the cells in your body because all your cells need Fat. The best fats are animal-sourced, and include beef tallow, pork lard, and butter. If you decide to stop using vegetable oils, which I strongly recommend, it will take approximately 680 days for them to be cleared out of your cells. Seed oils are very hard to avoid. They are in commercial foods, restaurant foods, packaged foods and drinks, and take years off of your life while causing misery with your health. Sugar is usually painted as the Bad Guy for health, but Sugar is by comparison a non-problem. The Seed Oils always seem to get a pass, but they are THE main source of poor health and disease. Use animal fats and stay healthy.

Avoid these oils at all costs:

Canola oil (Rapeseed oil)
Corn oil
Cottonseed oil
Grapeseed oil
Rice bran oil
Safflower oil
Soybean oil
Sunflower oil
additionally, the following oils are untrustworthy because of adulteration:
Olive oil (because most are adulterated with cheap vegetable oils and you can't tell)
Avocado oil (because they are adulterated)

Katzie
(Cancun, Mexico)
10/31/2024

Good info about the evils of seed oils! I just wanted to say that after being off seed oils for at least 6 months, a body could be out in the sun and never get sunburned!! Isn't that fascinating?! After I moved to Mexico I was stunned to see that I never ever got sunburn, even after being in the sun for a long periods. I could not figure out why and then Dr mercola said on a podcast that this was why. Dump the seed oils, people. I also have to say that a couple of times a month I eat from vendors that probably do use seed oils, but still no sunburns. Ya don't have to be too strict about it; it's hard to avoid them, but I use mainly coconut oil, pork lard and butter in my own kitchen. Anyway, I just wanted to let people know that no seed oils equals no sunburns and no dangerous sunscreen use either.

Replied by L
(Dallas, US)
08/14/2023

Hi Terry, are you still taking MB? I am trying to find the right dose and a convenient way to take it. Could you give me some tips, possibly? Also before food or after? I was also wondering what effect MB may have on a gastro-intestinal flora?

Replied by Bethany
(Maine)
11/13/2024

This is the best lifetime advice for all people. Avoiding seed oils is easy if you're eating a carnivore diet. There are thousands of us in the carnivore community who are turning their health around with a Proper Human Diet.

Broad Benefits

Posted by Bp (Edmonton, Ab, Canada) on 09/17/2011
★★★★★

I've only been taking methylene blue for about two weeks, so I can't yet speak to long-term benefits or side-effects. But its positive results for me in this little time have been remarkable.

I've been suffering with depression and numerous physical problems for several years, to the point of being nearly bedridden at times, and being unable to function productively more days than not. I've tried dozens and dozens of natural remedies, with only limited effect.

When I began taking the methylene blue, I had a couple of days of discomfort in the area of one kidney. But within a couple of days, this had subsided, and I currently have the strongest physical and mental health I've had in years! My mood is joyful, and I have much improved focus when reading. The pains in my spleen area have virtually disappeared, I can breath comfortably at rest (my breathing was laboured before), and I have gone from needing 9 or 10 hours of sleep a night to needing only 6 or 7 to get by comfortably.

MB isn't a cure-all -- I still have back problems, and skin issues, and some other symptoms from congenital/genetic issues. But, based on my own experience, I recommend trying it if you have had problems with candida or parasites, anything spleen-related, depression without obvious cause, persistent breathing problems, or thyroid/glandular disfunction.

I dilute one drop of the pet-store MB into four litres of water (two full 2-litre pop-bottles), and take between a half-cup and a full cup, with extra water added to further dilute the dose, once or twice daily. Since MB is used to disinfect standing water, it shouldn't need to be refrigerated, either.

Replied by Bp
(Edmonton, Ab, Canada)
11/13/2011
★★★★☆

I thought I would report back after a couple of months of pretty regular use (at least 4 or 5 doses per week). Unfortunately, the euphoria and enhanced concentration didn't persist past the first few weeks, and my depressive symptoms have returned to their previous level. However, as of this time, the pains in my left side (spleen region) that were my constant companion for a long time have still not returned, so I consider it a success by this measure alone. I also believe that it's having a positive effect on my sinus pain/pressure (a problem which I attribute to systemic candida -- a longstanding problem for me -- and/or a mold infection acquired from an unhealthy living environment).

Replied by Heather
(San Diego, Ca)
03/08/2013
★★★★★

Thank you for posting this. I'd been looking into Methylene Blue (MB) for antifungal/antibiotic/antiviral uses, and noted that it seemed to clear up brain fog and was being used in clinical trials for a variety of brain-related issues (which I have to some degree). I also had multiple painful cysts (one each on an ovary, liver, kidney, in diaphram area and a breast.) The breast one seemed to go away on it's own but the others persisted for 9 months, sometimes doubling me over in agony. Usually though, they only hurt if I or my doctor pressed on them.

After a week on MB, I noticed the abdominal area cysts hadn't been bothering me, so I began pressing on all the parts that hurt, and no pain. I'm assuming they are now cleared up. Note that two weeks prior to MB, I finally took a course of antibiotics, which may have helped, but the pain was still there, and they still hurt when I pressed on them even a week after discontinuing the antibiotics.

Other supplements I take are Lugols 5% (average 1 drop per day); daily, a half dose of a good quality, high b vitamin multi, vitamin D 1500-2000 per day, N-A-C, Milk Thistle, Lysine, 3-4 grams Vitamin C and melatonin; Zinc, selenium lithium aspartate (5 mg) are taken 3-4 x per week. Also, I've been faithfully making Ted's alkalzing formula 1/4 tsp baking soda with an acid (ACV, lemon juice, or for now, just the vitamin C crystals to take with the Methylene Blue). Additional baking soda taken on its own before bed.

Take a few low dose (usually 1/3 of lowest dose) Xanax and Trazadone for sleep or panic attacks as needed. (Once in past week.) Taking the MB in 2-5 drops, 2-3 x per day in the 0.1% solution recommended by this site (Ted). I've settled for now upon 2 drops but experimented a bit.

I've experienced reduced brain fog, increased ability to focus, recall of memories and vocabulary that were lost to the brain fog, deeper sleep, and less anxiety but not ruling out placebo effect (or the addition of Lysine) yet as I haven't been on it for months. I can only say that the cysts are not a placebo effect, as they were painful and I wasn't taking MB for them per se, although I did hope for improved general health due to possible viral/fungal/bacterial infection. I have traveled to jungles, etc. , in past and thought perhaps I picked up something US docs don't screen for.

Side effects I may be experiencing from Methylene Blue are headaches (mild, infrequent), dehydration - drinking lots more water, buzzing in brain - specifically the right side over temple, and sometimes on top of hear, stiffness in neck/ upper back. Except for the buzzing, the others may not be related at all. The brain buzzing is particulalry amplified by coffee and/or N-A-C. I've also been experiencing a buzzing in my lower legs (outside of calf) for a few days.

There's research on Methylene Blue that says it is an inhibitor of Tau protein aggregation. (From wiki: Tau proteins are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes.[1] When tau proteins are defective, and no longer stabilize microtubules properly, they can result in dementias such as Alzheimer's disease. http://en.wikipedia.org/wiki/Tau_protein)

Melatonin also reduces tau hyperphosphorylation, at least in rat brain studies, so I'm going to taper off of melatonin (I've taken 9 grams for a year) for a while. It might somehow be related to the buzz effect too.

That's my report. I fully expect that the mental benefits from my lose dose Methylene Blue experience will be a fail/placebo, but I'm going to keep it up for two or three more months, just in case.

Replied by Roec
(Los Angeles, Ca)
03/11/2013

Was wondering where you were able to get 5% iodine. I can get it online but hoped you found a store you can walk into and buy. I am aware of the law changes in 2007 that only one ounce of 5% can be sold at one time.

I have looked almost everywhere for it, in healthfood stores. No one has it. Whole Foods and Earwhone doesn't even have iodine other than the one help derived iodine and does not provide any percentages on the lable and the fluid is clear.

Replied by Heather
(San Diego, Ca)
03/14/2013
★★★★★

I can only find Lugol's online. Usually, I get the 2% and double the number of drops because 5% is harder to come by.

Just realized that I wrote I was taking 9 grams of melatonin. LOL! That would be an overdose for sure. I was taking 9 mgs, and have tapered down to 3 mg. Will continue tapering to 1.5 mg.

At this point, the brain buzzing has become barely noticeable on top of my head. That buzzing sensation in the legs and right side have stopped as well (those are areas that flared up with buzzing and pain once when I took doxycycline -so it's interesting to note) and it appears the other possible side effects - back pain, headaches, weren't related. I do suspect the interaction of melatonin with methylene blue (MB) was part of the buzzing issue. Regular coffee is definitely also an isssue in the buzzing, so my advice is avoid or drink decaf.

MB has not increased my energy levels but I still think it has increased my ability to focus and has perhaps reduced depression and anxiety as well.

I don't know how many miccrograms I'm getting of the MB with each drop at 0.1%. I think it could be 60 mcg. If anyone has a guesstimate, I'd really appreciate an approximation to assist with my research on scientific studies with MB.

Replied by G Smothers
(Oregon)
04/16/2023

You will want to get the USP grade, not use the pet store one. USP is more pure, free from heavy metal contamination. ✌

Cancer

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Posted by Kevin (Wilkesboro, Nc) on 08/02/2010

My dad was diagnosed with mantle cell lymphoma back in Feb 2007. He has been thru chemo several times and it's to the point now that he just can't stand the strong treatments and they aren't effective now anyway. We have always believed that God put natural methods here to cure cancer etc. And one of his friends told us about Mary Martin Sloop who back in the early to mid 1900's took methylene blue for cancer after the Dr. had cut her open and then sewed her back up because they said they couldn't do anything for her. Mary Martin Sloop went on to live 40 more years after taking the methylene blue. We have no idea how to get it, use it and would it even work for my dad now since he is in pretty bad shape. He is unable to eat basically as he has trouble keeping food down and is really weak. The Dr. gave him no more than a few weeks to live. Can you please let us know quickly if there is anything that would get him well. We don't want to prolong his suffering but we would love to get him back to his active lifestyle of bowling, biking and living for the Lord. Thanks and God bless, Kevin

Replied by Isabelle
(Garden Grove, Ca Usa)
08/03/2010

Dear Kevin, I am so sorry about this situation, my heart go out to you family. You can search this site on lymphoma, cancer, methylene blue etc.. And try to find the what and how by yourself but your time is more precious. Your best chance is to contact Ted directly. He is using methylene blue in his remedies plus a few other components to help with cancer he is extraordinarly knowledgeable and generous with his knowledge and patience. He can give you a protocol to follow right away and that will save you a lot of time. Any way you can get methylene blue in an aquarium shop. That is where I got it and diluted it by Ted specifications. May your faith and the force of the univers guide you to good result!

Replied by Ted
(Bangkok, Thailand)
08/11/2010
392 posts
★★★★★

Dear Kevin:

Methylene blue does effect cancer growth by turning the cancer tumors into aerobic, which stops their growth that way as cancer in general are aerobic. Methylene blue is acquired from stores that sell aquarium fishes. They usually have methylene blue 1%, whereby we reduce them by adding 1 parts methylene blue with 9 parts water, should get a relatively safe concentration. Then we can add methylene blue drops such as 8 drops and slowly add more so if there is no side effects. In Vietnam war they actually used far more methylene blue to treat malaria, such as methylene powder in milligram to gram doses. The methylene blue is synergistic with large dose vitamin C. What I do know for stage IV cancer, which is cachexia cancer, is B50 vitamin B complex, or B6 200 mg for example can reduce some of this cancer cachexia. The other is the use of Hydrochloric acid concentrated, at 8 drops per 250 cc of water and to that I will add between 4 to 8 drops of methylene blue and take this for an entire day until the cancer cachexia goes away. Another observation to restore the appetite and stopped cancer cachexia that I have found is B5 panthenol, or a possible replacement, pantothenic acid to be helpful. What I do not like about pantothenic acid is the calcium form since the get cancer worse. If it was possible for the methylene blue 0.1% is injected a 1 cc, into the tumor cells that could have done it's job also in staving off tumor, but that's just a theory, by interfering with cancer fermentation. In any case, there are other ways to resolving cancer cachexia such as megestrol which is progesterone hormone, if taken at fairly large dose such as 250 mg for example, or applied to the skin as safer means might actually stop the cachexia by neutralizing what they call TNF, which is a cachectin hormone that causes your inability to eat. The liver's inability to function from lactic acid is another problem that can lead to the condition also. A methylene blue is obtainable from a local chemist, a chemical company , a local aquarium shop, or a scientific supply store, or perhaps a school supply store where they do the slides to stain the samples using a 1% methylene blue solution.

Ted

Replied by Kevin
(Wilkesboro, Nc)
08/11/2010

Dear Ted,

I'm very unsure of what to do right now. My dad probably has a week or so at best to live and he is not eating, drinking very little and sleeps most of the time. I want to help him get well but I don't want to try something and prolong his suffering if we can't get him completely recovered. If it was your loved one and he/she was in this shape what would you do with the knowledge you have?

If doing something what exactly would you do?

Thanks for your time and may God bless you,

Kevin

Replied by Ted
(Bangkok, Thailand)
08/15/2010
392 posts

I would basically reduce his suffering by restoring energy and nausea. As mentioned I used clove oil and methylene blue. To restore appetite I used b50 and HCl and at least the case I was involved with simply did not want to die. While that case was given a few days to live she is doing fine after 3 years. Yet in another case just last week in similar circumstances she simply don`t want to live so nothing was done because she refused any treatment even though the natural treatment for cancer was a success and hence nothing was done so she died in few days just last week. It was the patient that really have their say and if not conscious it just depend on the family's decision.

Ted

Kelley
(CA)
07/11/2023

Hi,

Just was told that I have a thymus tumor... How can I treat this...
MB was helping but it now gives me air hunger...

Shay Rogers
(Lake Martin, Alabama)
10/26/2023

I would try ozone therapy with methylene blue via IV at least once a week maybe twice a week.

Also would do castor oil compress everyday for at least 4-6 hours.

Rid your body of sugar and pump your body full of oxygen, hyperbaric chambers.

Replied by Josecito
(Miami, Florida)
09/17/2010

Ted said, "They usually have methylene blue 1%, whereby we reduce them by adding 1 parts methylene blue with 9 parts water, should get a relatively safe concentration. Then we can add methylene blue drops such as 8 drops and slowly add more so if there is no side effects. "

What does 1 part exactly mean?

Replied by Tommy
(North York, On, , Canada)
09/17/2010

Hi Josecito, Ted spoke about how to dilute 1% MB into 0. 1% MB. One part of MB in 9 parts of water will dilute 1% MB and make it 0. 1%. So if you want to make 1L of MB 0. 1%, you have to take 100 ml of MB 1% ( one part ) and pour it into 900 ml ( 9 part) distilled water. Another example, if you want to make 500 ml MB 0, 1%, you take 50ml MB 0. 1% and pour into 450 ml of distilled water. There is a lot of ways how to make the volume you want, you have just to follow the right dilution ( 1:9). I hope that can help you.

Replied by MARIE
(TX)
02/17/2023

Fish store is the best place.

Candida

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Posted by Daboo (Amherst, MA) on 02/27/2014
★★★★★

I was taking Methylene Blue (12-13 drops in 8 ounces of water) with a thousand milligrams of vitamin C for about a week & I noticed the severity of my candida related itchy skin was reduced, I then upped my dosage by a few more drops per day (14-15 drops) in about 9-10 ounces of water, and a few hours later my stool was loaded with dead candida overgrowth! I normally have bad constipation but this time my "relief" was smooth and easy I was amazed. Also, I use the Methylene blue stain directly on my skin where I have itchy candida rashes, yes it stains! But only for a few days & most of it will wash off with soap and water, so use it where it cannot be seen, and it will take you itchy rash away with relief within 10-15 minutes and the relief will last for like a week, until the bugs send out a new invading force! I have also use Methylene Blue in more diluted parts for itchy skin in more visible areas with relief & I found it is also good for tooth aches.

P.S when I take it in strong doses your urine turns blue for about a day, but when you stop taking it it turns back to normal & I take vit C 500-1000 mill and have had no problems with my eye coloring, which I also heard is reversible if you should happen to have that happen to you.

Replied by Piro
(India)
03/10/2014

Was the cure PERMANANT?

Replied by James
(Liverpool, Uk)
12/09/2014

Please tell me what concentration of methylene blue you were using in your drops. I'm taking 1 drop 2. 4% but getting nowhere. Ted told me 5 to ten drops 1%, similar size to mine. Likely you are taking more than me.

Replied by Katerina
(Massachusetts)
04/15/2016

Methylene Blue - how much should be taken for the optimal results. I am using Kordon brand. Thank you!

Replied by Nadine
(Union Grove, Wisconsin)
07/20/2016
12 posts

I bought kordon. methylane.blue and wondering how to dilute this down seeing that it is 2.33 %. I am not good with percent as a lot of people may be.

Replied by Janet
(Indiana)
07/22/2016

Nadine,

Here is how we do it. We use that brand. The bottle should have powder in it. I fill the bottle to below the rim with spring or distilled water cap it and shake. Do this on a paper or glass plate it stains. Citrus cleaner or lemon removes stains. In a two oz. Dropper bottle I add 4 stoppers of the concentrate then I add water to that carefully it loves to overflow leave room to put dropper back in. It makes .01 % solution. Then you can use whatever your remedy calls for. Do not forget to add c with it when you take it. Janet

jeanna
(arkansas)
08/31/2022

I still don't understand your instructions, you say bottle what size bottle? and its a powder how much? I don't get percents either

Replied by Kate
(Shropshire)
08/13/2022

Helpful review, thank you.

I was just wondering how you know about candida expulsion?

Replied by Florencia
(Hayward CA)
08/31/2022

I take Tro blue/ just blue: cut it in quarter and place it between my gum and cheek. Turn your urine blue., nootropic to prevent Alzheimer's.

Florencia

EC: https://troscriptions.com/products/justblue:

16 mg of Pharmaceutical Grade (USP) Methylene Blue

Other Ingredients: Polyethylene Glycol (PEG), stevia extract, lou han extract, peppermint, silica, Bitter-BlocTM

https://troscriptions.com/products/bluecannatine - warning: has nicotine

5 mg pharmaceutical grade (USP) Methylene Blue
1 mg of USP (non-tobacco derived) Nicotine
50 mg of USP Caffeine
5 mg of Hemp Extract
Other Ingredients: Polyethylene Glycol (PEG), stevia extract, lou han extract, peppermint, silica, Bitter-BlocTM

Val
(Idaho)
12/08/2023

Polyethylene Glycol is dangerous.

Candidiasis

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Posted by Susanna (Skagit, Wa) on 12/22/2017
★★★★★

Research indicates Vitamin C may inhibit Methylene Blue's killing of Candida

Ted's advice on many areas of health have been of great assistance to me. I became interested in trying Methylene Blue for attacking my systemic Candida, and did some additional research. I came across a study that indicates that taking Vitamin C with MB may decrease the effectiveness of its impact on Candida. The research is found at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780517/

The relevant quote is halfway through the abstract: "... sensitivity of Candida cells to MB could be rescued upon the supplementation of ascorbic acid, an antioxidant." In the context of the abstract, this "rescue" seemed to be contrary to the intent of killing Candida cells.

Therefore, I began to take MB 1 drop twice a day (along with BHT), but taking ascorbic acid at least two hours later. My reasoning was taking such a small dose had no risk of side effects (coloring eye, etc.), but that any potential impact on Candida would not be lessened by the ascorbic acid.

I understand that Ted is not currently up to responding, but am hopeful that this information may help others, if you or someone may take a look at it and comment on how to take MB and Vitamin C (perhaps 2 hours between the two?).

Hoping this may assist others in recovery from Candidiasis;

Sincerely, Susanna

Replied by Sherri
(Texas)
01/03/2023

Note the study was by NCBI. I thought a world renowned doctor for research and use of MB stated that vitamin C BUFFERED ENHANCES MB effects. Forgive me if I'm wrong, and congratulations if it's working for you as a safer and less invasive means to help your conditions.

redragonmagic
(florida)
03/09/2024
★★★★★

I take MB with ascorbic acid (vit. c), 1% or 2.33% MB and a approx 1/8 tsp vit c powder in h2o. my MB dose is not always the same, as it depends on which dilution I use. if using 1%, then I take approx 20 drops 2x/day (so, 40 drops/day) from the supplied dropper to = 10mg 2x/day (20mg/day) for tinnitus, which it has helped. As an aside, my memory has improved. I was actually taking more MB but it gave me really loose stool so I backed off to this dose, which is fine. We'll see how it goes. I also take a day off from MB every so often.

Chronic Bladder Infections

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Posted by Kathryn (Eastern WA) on 04/30/2022
★★★★★

Hi Lynn,

I just finished reading an article by Dr Mercola who interviewed a Methylene Blue (MB) researcher. The researcher said there used to be pills of 60 mg MB that were used for UTIs. He put his mother on a dose of 1mg per kg body weight a day. He generally recommends 0.5mg/kg up to 1mg/kg (pharmaceutical grade as any others have heavy metal contamination) taken with 1000 mg of Vit C in the ascorbic acid form as it reduces the MB to be bioactive.

I just started taking 3drops in about 6oz of water per day, working up to a dose that I can feel better with. My rough calculation is that with 10mg/ml of MB, my weight of 118 in pounds becomes 53.5kg, divided by 2 for the .5mg/kg (or you can multiply by .5, your choice, same answer) becomes a good dose of 26.75mg MB which is then 2.675ml, which then is slightly over 1/2 teaspoon (conversion charts are amazing). It will take a lot of drops to get to that dose! But if a lower dose works, I'm happy.

Chronic Bladder Infections

Posted by MHO (Provo, UT) on 03/18/2022
★★★★★

Editor's Choice

I am an intermittent catheter user, therefore, I have chronic bladder infections. Ever since I began using Methylene Blue I have stopped getting UTIs. I use Methylene Blue 1% solution. The normal dose is 10 drops in water morning and night. I only need 2 drops morning and night. I use a straw to drink it so my teeth won't turn blue. It has the added benefit of stopping my candida symptoms.

Having said this, I am also very careful about what I eat: no sugar or fruit of any kind. I don't use any artificial sweeteners. I avoid wheat and other grains. I eat canned beans, eggs, fish, chicken, vegetables, and brown rice. I have to avoid nuts.

Replied by Lynn S.
(Colorado Springs, CO)
04/25/2022

Methylene Blue for Prevention of Chronic UTIs:

I bought MB from Botany Biosciences. Bottle states 10mg/ml. I weigh 130 pounds-any suggestions for dose? Do I need to take Vitamin C to prevent staining as others suggested? I am tired of taking antibiotics every 3 months-and has affected my gut health. Thank you!

RW
(OH)
04/27/2022

Hi Lynn,

My neighbor and some of her relatives had trouble with recurring UTIs, and she found a probiotic that is sold on Amazon to stop this in everyone who has tried it. We also had a friend who had the same problem and was very ill, so we gave her several packages that my neighbor had on hand, and she is now completely well, as long as she takes the probiotics. She thinks it is worth the cost to stop getting the UTIs. It might be worth a try.

https://www.amazon.com/Medix-Synbiotic-365-30-Capsules/dp/B088VLBX4T

Best wishes!

Beckie
(California)
10/26/2022

I know that probiotic and it also contains a very powerful cranberry concentrate along with the probiotics. It sure does get good reviews.

Naomi
(NC)
03/23/2023

Would that be D-mannose? That stuff works wonders for UTI's.

AZJJ
(AZ)
07/23/2023

Yes, it is great... BUT... if you do get a UTI in spite of using D-Mannose... I used chlorine dioxide solution (CDS) to cure a nasty UTI in just 2-3 days... nothing else.

Just an FYI! Dr. Kalcker is the expert, if you want to do any research... amazing stuff!

Replied by Beckie
(California)
10/26/2022

Hi MHO - Do you use any ascorbic acid with your MB?

Replied by Wycliff
(Little Rock, AR)
06/13/2024

I was wondering why with UTI this person does not eat sugar, fruit or sugar substitute? Do these items make UTIs worse?

Cindy
(Illinois, USA)
06/14/2024
523 posts

I've been reading about recurring infections as I've been looking for a reference I lost track of...apparently, infection can "hide" in areas of heavy metal deposits and regenerate from there. Apparently, heavy metals tend to accumulate in areas that are already compromised, providing unfriendly microbes with shelter from the immune system.

In cases of chronic dehydration - which it is thought that most people are chronically dehydrated to some degree - the body is in a sustained "emergency mode" of water rationing during which some systems are slowly and steadily sacrificed to dehydration to assist the body in getting as much hydration to critical systems as possible.

This would explain why a rehydration scheme has such favorable effects on such a huge variety of different issues and systems. And I reckon a system that is slowly being sacrificed would be a safe place for heavy metals to accumulate. Otherwise, they'd simply be identified and flushed out as "foreign material".

Chronic Fatigue

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Posted by Cynthia (California) on 09/12/2016
★★★★★

Editor's Choice

I found that methylene blue works great for chronic fatigue. It was like someone hit my on switch. My energy level and thinking improved drastically and I was easily able to give up caffeine. However, the reason why methylene blue was able to work so well for me is that my chronic fatigue was due the fact that methylene blue treats mitochondria damage, and I have mitochondria damage from taking Cipro. Never take Cipro.

Replied by Angela
(England)
05/27/2024

Hi, please can I ask about the dose you take? My son suffered hypoxia during a general anaesthetic and the mitochondrial coating of nerves was stripped. He was paralysed for some time until the mitochondrial coating regrew/regenerated. Since then he has had severe anxiety, OCD and fatigue. Many thanks

Contaminated Methylene Blue

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Posted by Chickkie (Chelmsford, Ma) on 07/25/2014
0 out of 5 stars

I found out the hard way. Methylene blue is sometimes deliberately contaminated with arsenic, possibly to prevent us from benefiting from a safe effective product. The type I bought had a warning label not to be used in food producing fish. I called the store I bought it from, they said it did not have arsenic. This was a lie.

I suffered greatly from severe arsenic poisoning. I wish there was a way to be sure the source was pure, because aside from the arsenic, methylene blue was great stuff.

Replied by Brandon
(San Jose, Ca)
02/03/2015

What was the brand that caused arsenic poisoning?

Contraindication

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Posted by Pat (Salem, Oregon) on 01/20/2012
★☆☆☆☆

WARNING!

After reading your website, I was excited to try out the methylene blue for my yeast and "brain fog". I followed instructions, taking it with powder vit c and baking soda. I took it only one time because in researching a bit more, I saw where taking Methylene blue with anti depressants can cause serious problems with the serotonin in the brain.

"Although the exact mechanism of this drug interaction is unknown, methylene blue inhibits the action of monoamine oxidase A—an enzyme responsible for breaking down serotonin in the brain. It is believed that when methylene blue is given to patients taking serotonergic psychiatric medications, high levels of serotonin can build up in the brain, causing toxicity. This is referred to as Serotonin Syndrome. " (food and drug administration webpage)

I have been on effexor for 10 years, and although I plan to go off this slowly in the summer, it looks like I will not be able to use the methylene blue as planned.

Was this on your website and I missed it? If not, you might want to add this information. I'm glad I caught it, but very disappointed I cannot benefit from taking the methylene blue. Any other suggestions?

Thank you, Pat

Replied by Randy
(Myrtle Beach, Sc)
01/22/2012

hi Pat, Very good point you made. I know I had mentioned this in one of my previous posts. While we are on this topic... Someone also has to be careful taking Resveratrol and/or Curcumin along with any antidepressant because Resv and Curcumin also have some MAOI properties. Just a heads up.

Replied by Wat
(Digby, Nova Scotia)
08/29/2012
10 posts

more likely mis-information and half truths from FDA and Big Pharma research studies... In any event once your clean of their poisons you should have no further excuses NO! So use it then.

Cytokine Storms

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Posted by Tim (Minnesota) on 01/15/2021 8 posts
★★★★★

The only drug known to inhibit the excessive production of reactive species and cytokines is methylene blue, a low-cost dye with antiseptic properties used effectively to treat malaria, urinary tract infections, septic shock, and methaemoglobinaemia.The relatively poor efficacy of anti-cytokine drugs is explained by the fact that they act on one or a few of the dozens of cytokines involved, and because other mediators of inflammation – reactive oxygen and nitrogen species – are not targeted. When produced in excess, reactive species cause extensive cell and tissue damage.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7728423/

Replied by Bill
(Philippines)
01/15/2021
★★★★★

Using Methylene Blue is not just a hypothesis.Regarding using methylene blue(MB) against COVID-19 ARDS, there is an Indian doctor, Dr Deepak Golwalkar, who, as a pulmonologist and lung specialist, has been using his nebulized/sublingual MB treatment for quite a while and with great success for his pneumonia patients and for his COVID-19 patients with ARDS. Here is his website, which details his treatment:

https://medium.com/@dr.deepak.golwalkar/treatment-for-covid-19-using-methylene-blue-d23fc5a31a4d

Interestingly, Dr Golwalkar also uses exactly the same concentration of MB for nebulizing -- 0.1% methylene blue -- which is the same concentration that Ted from Bangkok recommends.

Replied by Dame Nikki
(California)
08/23/2021
★★★★★

from: https://pubmed.ncbi.nlm.nih.gov/27031833/

DMSO Represses Inflammatory Cytokine Production from Human Blood Cells and Reduces Autoimmune Arthritis

Abstract

Dimethyl sulfoxide (DMSO) is currently used as an alternative treatment for various inflammatory conditions as well as for cancer. Despite its widespread use, there is a paucity of data regarding its safety and efficacy as well as its mechanism of action in human cells. Herein, we demonstrate that DMSO has ex-vivo anti-inflammatory activity using Escherichia coli- (E. coli) and herpes simplex virus-1 (HSV-1)-stimulated whole human blood. Specifically, we found that between 0.5%-2%, DMSO significantly suppressed the expression of many pro-inflammatory cytokines/chemokines and prostaglandin E2 (PGE2). However, a significant reduction in monocyte viability was also observed at 2% DMSO, suggesting a narrow window of efficacy. Anti-inflammatory concentrations of DMSO suppressed E. coli-induced ERK1/2, p38, JNK and Akt phosphorylation, suggesting DMSO acts on these signaling pathways to suppress inflammatory cytokine/chemokine production. Although DMSO induces the differentiation of B16/F10 melanoma cells in vitro, topical administration of DMSO to mice subcutaneously implanted with B16 melanoma cells was ineffective at reducing tumor growth, DMSO was also found to block mouse macrophages from polarizing to either an M1- or an M2-phenotype, which may contribute to its inability to slow tumor growth. Topical administration of DMSO, however, significantly mitigated K/BxN serum-induced arthritis in mice, and this was associated with reduced levels of pro-inflammatory cytokines in the joints and white blood cell levels in the blood. Thus, while we cannot confirm the efficacy of DMSO as an anti-cancer agent, the use of DMSO in arthritis warrants further investigation to ascertain its therapeutic potential.

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Methylene Blue Health Benefits

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Health Benefits of Methylene Blue

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Methylene Blue Dosage and Dilution Instructions

Proceed With Caution: Methylene Blue's Potent MAO Inhibition and Potential Drug Interactions

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Diluting Methylene Blue Tips

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Anxiety, Panic Attacks, Intestinal Cysts

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Be Careful - It Stains Surfaces!

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Methylene Blue
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Methylene Blue
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