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Re infant who has had lots of antibiotics;
The discomfort he's experiencing could be from a fungal infection/or candida. Antibiotics in quantity will nearly always guarantee fungi.
Consider nystatin. That is a prescription drug so your MD must prescribe. If me, I'd also try Colloidal Silver. Read up on it's benefits. CS can kill fungi; I have so experienced. CS is positively charged as is beneficial bacteria which is why (one pro explained to me) ... which is why CS does no damage to the beneficial bacteria. But CS is draws to fungi and bad bacteria (negatively charged).
How much for a child? Don't know. But a full dose for me would be two tablespoons three times daily. If my child responded well in a few days using a dropper to administer, then I'd keep it up to see if in a week he was better. CS would have to be administered for months to finally kill a system wide infection.
Also child might have developed a reaction to hard to digest carbs, such as wheat based; and remember, sugar based foods (fruit juices) definitely feed the fungus. So he needs to be off such sugars... so no "sippy cups" filled with juices.
Toddler Whining
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Your grandson has had a bit of a rough start! Dave has good advice regarding the fungal possibility and solutions for it.
Some additional thoughts on dealing with whiny behaviour:
Daily outdoor play and sunshine daily are good for the mood and attitude, even toddlers.
A lot of screen time (tv and computer) can make little ones cranky. The American Academy of Pediatrics recommends no screen time for children under two.
One of my toddler mottos is: Feed them when they are hungry, put them to bed when they are tired. Being tired or hungry increases whining in mine and most.
Sometimes they get into a whiny habit. When this happens, I will answer a whine with, "Nice voice please." said with a smile in a very pleasant way. I wouldn't make a battle out of it, just nice reminders.
Sometimes children get a little fussier when they are going through changes (learning to walk, talk, etc.) Sometimes it is helpful for a parent to know, "This is going to pass." Teething also makes mine fussy. If the toddler is drooling a lot, this could be it.
Please let us know how it goes!
~Mama to Many~