★★★★★
First, because there seems to be so much dosage confusion about MB percentage strength and number of drops used, I'm going to use a completely different quantitative method that determines how many milligrams or how many drops to supplement MB with water. There has been much of confusion over this.
But first some information that I have found to be extremely useful in helping to more fully understand the effective dosage amounts of MB needed for particular ailments :
1 drop of 1% Methylene Blue contains 0.5 mgs of MB.
1 drop of 0.1% Methylene Blue contains 0.05 mgs of MB
1 drop pf 2.33% Methylene Blue(Aquarium version ) contains 1 mg(approx.)
A half teaspoon of MB is 40 drops.
A full teaspoon of MB is 80 drops.
So armed with the above helpful definitions, I will now only describe MB dosages in milligram amounts only. Doing it this way eliminates all the confusion(and myths) of how you should use 0.1% or 1% or 2.33% MB. After all, it's the dose of MB powder in water that you supplement that is all-important -- not the percentage of MB in your dropper bottle. Right?
Ted from Bangkok has also maintained in his MB posts that supplementing the cheaper aquarium version of Methylene Blue is certainly good enough and pure enough for supplementing in humans. But if that last statement makes some readers balk in fear of "heavy metal impurites" then it's perhaps also useful to appreciate that fish live and breath in water and humans breath air. But water is a much more dense medium than air. And that means that fish are much more sensitive to poisons, heavy metals etc in their water than humans are. So if the aquarium version of MB is good enough for the more sensitive fish then it should certainly follow that aquarium MB is pure enough for us humans as well. And that's also why I've been using the aquarium version of MB, without any problems whatsoever, for over 10 years now.
Other things to remember about MB is that low MB dosages will be good enough to help give you energy and to help MB act as both an antioxidant and antimicrobial for the brain, thus helping to increase and maintain mental cognition as well as helping to prevent dementia(Alzheimer's Disease, Parkinson's Disease etc). However, much larger doses of MB will be required to kill viruses or bacteria, cure malaria, kill fungus, kill parasites, treat Methemoglobinemia, help remove blood clots etc.
But what do I mean when I say take a low dose of MB in water? -- And here is where all the confusion happens. I've read that for some people 2 drops of 1% MB(which is equivalent to 1 mg MB powder on water) is enough to fully energize them. I've also read where other people need to take as much as 16 mgs or even 100 mgs of MB(which is still a low dose for MB) to get energized. The point that I'm making here is that you will normally always have to find your own MB dose that works for you personally.
My own dose, which suits me for getting more energy and obtaining the cognitive benefits from using MB, is based on Dr Golwalkar's method that he has been using over the years to treat and cure both tuberculosis and COVID-19. He uses a teaspoon of 0.1% Methylene Blue for nebulizing(which is equivalent to 4 mgs MB powder in water) and he also recommends taking a half teaspoon of 0.1% MB orally as a sub-lingual dose(which is equivalent to taking 2 mgs MB powder in water).
My own everyday MB dose is slightly different to Dr Golwalkar's sub-lingual dose. I just add half a tablespoon of water to a small empty glass and then add 4 drops of 2.33% Methylene blue(which is equivalent to taking approximately 4 mgs of MB powder) and supplement that twice a day. But I have also taken the equivalent of more that 25 mg MB powder per day without a problem. I would also recommend using Dr Golwalker's recommendation of using 5 mls or 1 teaspoon of 0.1% MB(which is equivalent to 4 mgs MB powder in water) in a nebulizer two or three times a day when infected with COVID-19.
Some more MB facts for you. When you supplement Methylene Blue then between 75% and 80% of the MB taken orally is directly and quickly absorbed into the blood. Methylene Blue has a half-life in the human body of about 6 hours. That means that half the amount of MB that you supplemented will still be in your body after 6 hours. It's for reason of this persistence of MB in the body that I would at least advise that for low dose MB you should at least take one day off a week to reset your system and get rid of all the MB in your body.
I've also found an easy way of converting Methylene Blue from its blue oxidant form to its colorless reduced form. I will, for instance, add my 4 drops of Methylene Blue to a little water in a glass for sublingual supplementation. Then I would add a very small amount -- a tiny amount!! -- of Ascorbic Acid to the MB and walk outside and let the sunlight quickly convert the blue oxidant form of MB to it's colorless reduced form and just take it like that without giving me a blue mouth. I've also used the reduced or colorless MB form on skin problems without any blue coloring occurring. It works well and MB is also rapidly and easily absorbed into the skin.