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Selenium and Type II Diabetes Risk
Perhaps the selenium supplementation caused an already low level of chromium and/or vanadium to go so low as to cause diabetes, as these two minerals are used by people to treat their diabetes.
Selenium and Type II Diabetes Risk
Selenium and Type II Diabetes Risk
A very reliable first stop for nutrition information, again, imho, is the Linus Pauling Institute. This article http://lpi.oregonstate.edu/infocenter/minerals/selenium/
addresses this finding, but notice the educational approach on the entire subject of Selenium as it relates to the human body.
I think it was the famous musician John Denver who saw several specialist for an infertility issue w/ no help, when eventually he found that his problem was simply a Selenium deficiency. This is that bias problem again.
Selenium and Type II Diabetes Risk
http://umm.edu/health/medical/altmed/supplement/selenium
Has anyone else heard of this? What do you think? Thank you.
The most serious adverse reactions seen in Lialda clinical trials or with other products that contain or are metabolized to mesalamine are:
* Renal impairment, including renal failure
* Mesalamine-induced acute intolerance syndrome
* Hypersensitivity reactions
* Hepatic impairment, including hepatic failure "
"In two 8-week placebo-controlled clinical trials involving 535 ulcerative colitis patients, 356 received 2. 4 g/day or 4. 8 g/day Lialda tablets and 179 received placebo. The most frequent adverse reaction leading to discontinuation from Lialda therapy was exacerbation of ulcerative colitis (0.8%). Pancreatitis occurred in less than 1% of patients during clinical trials and resulted in discontinuation of therapy with Lialda in patients experiencing this event. " Source:http://www.drugs.com/sfx/lialda-side-effects.html
Regarding taking iodine for your problems -- I am wary of advising this now because I have no idea what the contraindications would be when taken with Lialda. So best to ask the endocrinologist about this.
You can get a hair analysis done at any naturopath clinic in your area -- its not expensive.
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Also, I take Lialda so maybe that is affected my liver/kidney, besides that I take vit d, zinc, cysteine, lysine, thats it! Well, at least the levels were low. Im getting them checked in 3 weeks again.
Also, do you know a reliable place to get hair analysis done? Thanks!
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* If your Reverse T3 and Reverse FT4 levels are too high -- this will not be reflected in any of the readings you have so far obtained from your blood and urine levels. This can only be obtained from separate and specific RT3 and RT4 readings from the blood. If RT3 and RT4 are high then the absorbtion of FT3 & FT4 at the cellular level will be low -- both RT3 and RT4 inhibit FT3 and FT4 abroption throughout the body -- giving symptoms such as low energy, lethargy, brain fog etc. Therefore as I've said before -- You must get your RT3 & RT4 levels checked to be sure.
* High RT3 & RT4 levels, high albumin levels and alkaline phosphate levels all tend to indicate problems with the liver or kidneys -- not the thyroid. So get your liver(AST, ALT levels etc) and kidney checked out.
* A low TSH output with normal FT3 & FT4 could also indicate problems with the pituitary gland. Both the pineal and pituitary gland are absorption targets for heavy metals and for fluorine and bromine which can definitely effect hormone output levels. So you might need to detox your pituitary gland using green tea, chlorella and cilantro as advised on this site.
* You also have candida and colitis and this is also reason enough to cause debillitating effects on your thyroid and would also indicate that your body needs detoxing. Candida always affects and suppresses thyroid performance over time.
* Candida always drags down the thyroid. And if you don't get rid of the candida, your thyroid and colitis problems may well worsen over time.
Supplementing organic aloe vera juice and regular supplementation of food grade Bentonite clay should help the colitis, but -- from my own experience -- you will have a tough time curing colitis and your thyroid problems if you do not get rid of the candida first. See the Anti-Candida Protocol shown in the link.
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I do have Ulcerative colitis, a white tongue, and I do believe candida. Would iodine be wise to take? Also, should I be concerned about the Alkaline phosphate and albumin? Thanks again!
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RT3 and RT4 are produced at a constant output level to further balance the ratio and uptake of mainly FT3/FT4 in the body. This balancing/adjustment of FT3 and FT4 with RT3 and RT4 is a normal body mechanism which mainly happens in the liver. RT3 and RT4 work at the cellular level -- binding to T3 and T4 tissue sites to deiberately inhibit and balance FT3 and FT4 uptake. So if the clearance or regulation of RT3 and RT4 is either inadequate or excessive then this can also cause apparent thyroid problems and symptoms.
RT3 and RT4 clearance problems are normally concerned and associated with liver/kidney problems and not the thyroid.
So, if you still believe that you have hyper- or hypo-thyroid symptoms, perhaps best if you get an RT3 and RT4 check to further confirm if there are any problems in this area.
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First, selenium is essential for the manufacture of T3 and T4 to prevent the anti-body auto-immune response. Thyroglobulin stored in the thyroid is converted to T3 and T4 by an enzyme called thyroid peroxidase. And hydrogen peroxide -- a free radical metabolite that is normally always produced -- is given off during this reaction. Normally glutathione peroxidase -- an anti-oxidant -- neutralizes and prevents build up of hydrogen peroxide free radicals in the thyroid cells. However, selenium is the central metallic atom for glutathione peroxidase(GP) so if selenium is depleted in diet you may not have enough GP to prevent thyroid cell free radical damage and the inevitable anti-body autoimmune response(thyroid nodule formation and inflammation). So you must always take selenium with higher dose lugol's iodine for this reason.
Secondly, selenium is also involved in the conversion of T4 to the more active T3 form. So if selenium is depleted in the body, there will therefore be higher T4 and lower T3 readings. T4 is also used in the feedback loop with the pituitary gland -- so a false high T4 reading will immediately act to suppress and reduce both T3 and T4 production in the thyroid -- giving an overall hypothyroid effect.
This is why -- if you are taking higher dose lugol's iodine -- you should always follow The Iodine Protocol. Every single one of the nutrients in this protocol is there for a reason. For instance, magnesium is in the protocol to regulate excess calcium in the body(excess calcium inhibits iodine uptake) and magnesium is also involved as a coenzyme with l-tyrosine that converts iodide to iodine for initial storage in the thyroid. So, if you are defficient magnesium in your diet -- you also run the risk of being hypothyroid. The western diet is also well known to be defficient in both magnesium as well as iodine.
A normal maintenance dose of selenium is between 100 mcg and 200 mcg per day depending on your diet.
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TSH w/ Reflex to FT4 was 0.39 (0.40-4.50 is normal)
T4, Free was 1. 4 (0.8-1.8 is normal)
T3 uptake was 35 (22-35% is normal)
Alkaline Phosphate was 38 (Low) (40-115 is normal)
Albumin/Globulin ratio was 2. 2 (high) (1.0 - 2.1 is normal)
Thanks again!
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General Feedback
I do take selenium supplements but I just started them several days before, besides that there is not much else of selenium in my diet.
I read there could be a connection between high selenium and diabetes but I have a well controlled diet and my fasting glucose was 86 and A1C was well within the normal range.
The other thing I read was that Selenium and thyroid work together... Something along those lines. I just couldn't understand if I would be hypothyroid or hyper in relation to selenium being high.
Any info would be helpful, thanks!
I gave it to someone who had a flu and had been taking antibiotics for several days with NO change - in a matter of about 4 hours their flu was GONE. I have also over the years treated my pets with it (putting it in their water). I have given it to my cats when they were sick and I didn't know why - and fixed them up immediately. Another thing it is very good for - you never have to worry about eating some bad food - on the few occasions I did, colloidal silver cleared up the problems immediately.
It is a huge disservice to tell people not to use it - it is very reasonably priced and if properly made CANNOT build up silver in your body.
Thyroid Issues
Regarding Earth Clinic's query about "Se" in someone's post. It stands for Selenium which is extremely helpful for those who have problems with their thyroid. By the way, I love this site and check it regularly. I've learned so much. Thank you!
Thyroid Issues
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I was taking:
200mcg.(mcg.= micrograms) through a supplement.
100mcg. was in my multi-vitamin/ which I knew there was some, but, that is 143% of our daily recommended intake.
1 brazil nut equals your whole recommended dietary intake. I was eating a handful a day!
You also get your daily amount in food: Fish, tuna, eggs, bread, brown rice, oats, turkey, and other nuts.. I did not know any of these extra ways of getting Selenium.
My daily intake was probably 700 - 900 mcg a day, or more! 200mcg. is the recommended daily amount. It also says some people can take up to 400mcg daily, and over 800mcg. could be toxic, and you could get Selenosis!
Also Vitamin E taken at the same time as Selenium, enhances the Selenium! Which I was taking the two at the same time!
After 4 days of not taking Selenium supplements, I am about 80% better.
Here is a website for further info on Selenium:
http://dietary-supplements.info.nih.gov/factsheets/selenium.asp