I wonder, if the melatonin, applied locally to the skin could help for skin cancer also. Thank you for your insights.
★★★★★
' Hi Art,
My scalp eczema usually flares up in January and February. I put the melatonin lotion on it...guess what? All gone and no roughness or itchiness...yay! '
This is a new indication for me as I have not heard from anyone else that it has helped their scalp eczema before this.
Art
Alleviates Nerve and Muscular Issues
You are very welcome!
Thank you very much for the feedback on melatonin lotion and I am sorry to hear of your diagnosis, but very happy that it is helping you so much! The positive feedback I am getting from a growing number of friends who are testing it has been impressive, as are your results!
I would just like to mention that among the myriad of health effects that melatonin has, it also has anticarcinogenic effects of its own as well as synergy with chemo and radiotherapy while helping to reduce the negative effects of chemo and radiotherapy. It also crosses the blood brain barrier when taken orally and possibly topically.
Thank you again, Deborah and best wishes!
Art
Alleviates Nerve and Muscular Issues
★★★★★
I have stage IV cancer with Lepto Menengeal. It has caused several nerve and muscular issues. A friend and I made this lotion and it is incredible. Long story, short; my feet absolutely do not tingle anymore. I use the TML twice daily. The second time we made it using beef tallow instead of cetaphil. That requires a little different method to mix, but I prefer a creamier thicker lotion. Both require some essential oils to overcome the smell. The cetaphil lotion smells like gin and the tallow one smells like beef and required a bit more lavender. The smell does dissipate once it's applied to the skin.
This stuff is amazing. It works! Thank you so very much! What a God send!
I am almost pain free at this point. This is very unusual for me given that the weather has been very cold. That usually exacerbates my arthritis. At this point I don't see any swelling in my back vertebrae. They usually swell first and then hurt like the dickens. I put the lotion on once in the morning and once before I go to bed. I use stopain with it. The swollen joints in my fingers have started to decrease in size and are no longer sensitive to the least touch...yay! I should have taken a before and after picture. The bumps on my finger joints have almost decreased by half size! I still have some back pain if I stand on my feet too long (more than 20 minutes) in a stationary position. So I try to keep moving.
Art
Back Pain Relief
Thank you so much for all of the information. I have ordered the hesperidin and I have the curcumin and resveratrol. Haven't ordered the piperine yet but will when I can. God bless you for your generosity in helping everyone you that you do. I will keep you posted on my results. And thanks again for all you do to help others!
Melatonin Lotion Feedback
Yes, vodka can work as substitute for gin, however a friend recently wrote me that when she ran out of gin, she tried using vodka to make her melatonin lotion and for some reason, she found that it required significantly more vodka to dissolve the melatonin and this ultimately made the finished lotion much more watery. Both products were labeled 80 proof, so it is hard to understand this discrepancy. She said she would go back to gin in her future batches as she is having very good benefit from the lotion she had been making with gin.
It is important to dissolve the melatonin in order to end up with an effective melatonin lotion.
Please come back and let us know how melatonin lotion works for you.
Art
Melatonin Lotion Feedback
Of course I am of the opinion that melatonin seems relevant in the discussion of any type of cancer because of its multiple methods of action when it comes to cancer. There are many studies which discuss these methods of action of melatonin, so I have not linked to those as you have probably already read many of them.
I will link to a few studies that may be of interest to you :
HESPERIDIN
https://www.mdpi.com/1420-3049/28/13/5152
Here is a relevant study quote :
Hesperidin, a flavonoid commonly found in citrus fruits, with its potential antioxidant, anti-inflammatory, and hepatoprotective properties, and cardio-preventive factor for disease prevention, is well-known. Furthermore, its anticancer potential has been suggested to be a promising alternative in cancer treatment or management through the modulation of signal transduction pathways, which includes apoptosis, cell cycle, angiogenesis, ERK/MAPK, signal transducer, and the activator of transcription and other cell signaling molecules. Moreover, its role in the synergistic effects with anticancer drugs and other natural compounds has been described properly. The present article describes how hesperidin affects various cancers by modulating the various cell signaling pathways.
https://onlinelibrary.wiley.com/doi/full/10.1111/jcmm.17902
Here is a relevant study quote :
Hesperidin showed significant anti-angiogenesis and anti-proliferative effects in mice bearing 4T1 breast cancer, suggesting this compound as a potential treatment either with or without standard treatment (doxorubicin) to be used in future clinical research. The role of hesperidin as an inhibitor of angiogenesis, tumour growth and metastasis was confirmed in this study. It is suggested to consider clinical studies to investigate the effects of this agent in humans.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8626310/
A relevant quote from the review :
In summary, hesperidin and its aglycone hesperetin have good in vitro anti-cancer activities in BC models based on their inhibition of cell proliferation, migration (hesperidin only) and BCSCs (hesperidin only) as well as their induction of apoptosis and cell cycle arrest. In in vivo BC models, they exert their anti-cancer effects by inhibiting tumour growth, metastasis (hesperidin only) and neoplastic changes in tissue architecture (hesperidin only). The co-administration of hesperidin with doxorubicin or tamoxifen as well as the co-administration of hesperetin with doxorubicin or letrozole can enhance the anti-BC effects of the clinically available anti-cancer drugs.
PIPERINE
https://onlinelibrary.wiley.com/doi/epdf/10.1002/ptr.7291
A relevant quote from the review :
Piperine (PIP) is an alkaloid found primarily in Piper longum, and this natural compound has been shown to exert effects on proliferation and survival against various types of cancer. In particular, PIP has potent inhibitory effects on breast cancer (BC), the most prevalent type of cancer in women worldwide. PIP targets numerous signaling pathways associated with the therapy of BC cells through the following mechanisms: (a) induction of arrest of the cell cycle and apoptosis; (b) alteration of the signaling protein expression; (c) reduction in transcription factors; and (d) inhibition of tumor growth. BC cells have the ability to resist conventional drugs, so one of the strategies is the combination of PIP with other phytochemicals such as paclitaxel, thymoquinone, hesperidin, bee venom, tamoxifen, mitoxantrone, piperlongumin, and curcumin.
So the above article suggests that while piperine has anticancer effects, it may also work with hesperidin and curcumin against cancer.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7432303/
Here is a relevant study quote :
In conclusion, this study demonstrated that resveratrol, curcumin and piperine exposure results in cytotoxic effects in MCF-7 cells, associated with decreasing GLO1 activity and mitochondrial cell damage. Other aspects involving the action of these compounds in glyoxalase system enzyme expression as well as the mRNA expression of glyoxalases 1 and 2 should be further investigated as chemotherapeutic targets.
CURCUMIN
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10679154/
Here is a relevant quote from the link :
Curcumin can be very effective and free of severe toxicity75. Curcumin has multiple medicinal properties and can interact with several molecular targets and intracellular signaling pathways76. However, poor bioavailability limits its therapeutic effects. Curcumin analogs and their various formulations, including nanoparticles and liposomes, are extensively studied for maximum effectiveness.77, 78.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10675183/
Here is a relevant quote from the link :
The positive feedback loop in the breast TME contributes to the aggravation of cancer. Particularly, EMT facilitates the invasive and metastatic potential of tumors, which can be mediated by the NF-κB signaling pathway [46]. During EMT, cellular behavior undergoes notable shifts, with diminished expression of epithelial markers and increased mesenchymal-like phenotype [47]. To evaluate the impact of Cur-CM on EMT, the migratory and invasive capabilities of MCF7 cells were determined. Remarkably, treatment with Cur-CM significantly reduced the mobility and migration potential of MCF7 cells compared with Con-CM treatment. To further explore the molecular mechanism underlying such a phenotype, we examined the expression levels of EMT markers. E-cadherin, an epithelial cell marker, was upregulated following Cur-CM treatment. In contrast, the expression of N-cadherin and fibronectin, both indicators of mesenchymal characteristics, was significantly downregulated after Cur-CM treatment. These results explained that curcumin modulated the EMT by disrupting the CXCL12/CXCR4-mediated transformation of ADMSCs into CAFs and suppressing the breast TME from further progression.
Since you mentioned that you are already taking Resveratrol and Quercetin, the following mouse model of breast tumor study may be of interest to you since it used those two in combination with Curcumin in the study and it gives human equivalency dosing :
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10432483/
Here is a relevant study quote :
BALBc mice were injected 2 × 105 4T1 cells subcutaneously. The treatment plan was divided into three types. The mice in the Treated A group were given RCQ by intragastric administration for 30 days after subcutaneous injection of 4T1 breast cancer cells. The mice in the Treated B group were consumed RCQ for 15 days for prevention, then injected subcutaneously with 4T1 breast cancer cells and continued to gavage RCQ for 30 days. The mice in the Treated C group were consumed RCQ for 30 days for prevention, then injected subcutaneously with 4T1 breast cancer cells, and continued to gavage RCQ for 30 days. Each mouse was fed 60 mg kg−1 orally five times a week, 200 μL each time. RCQ in PBS plus 1% DMSO was prepared by dilution from Res, Cur, and Que solutions in DMSO. The control group was fed with PBS plus 1% DMSO. From Monday through Friday, RCQ was given to the mice five times a week, once per day. In previous studies, the non-toxic dose of these antitumor polyphenols in tumor mice was generally between 5–140 mg kg−1. In this study, the dose of RCQ was 60 mg kg−1 (including 24 mg kg−1 Res, 24 mg kg−1 Cur, and 12 mg kg−1 Que), which was the non-toxic dose. Grapes contain the highest content of polyphenols, which can reach 50–100 mg kg−1. The recommended dosage for humans is 0.3–1 g per day, equivalent to 3 kg of grapes, but full amounts of polyphenols can be obtained by taking extract capsules. According to the body surface area method, the conversion factors between different animals and humans are different. The dose given to mice was about 12.3 times that given to humans. 60 mg kg−1 (including 24 mg kg−1 Res, 24 mg kg−1 Cur, and 12 mg kg−1 Que) translated into an edible human dose of 738 mg/day (including 295.2 mg Res, 295.2 mg Cur, and 147.6 mg Que). On the other hand, applying allometric principles and taking different caloric demands of mice and humans into account66–68, it is possible that, related to body weight, humans need an approximately 5–10-fold lower dose of RCQ than mice for an effect. Therefore, the intake of RCQ for humans can be reduced as appropriate.
WARNING
Regarding melatonin, it dissolves better in DMSO than ethanol, but DMSO can carry unwanted chemicals through the skin so it would not be compatible with other ingredients such as the Cetaphil lotion itself might have. I'm just adding this warning because you may have been thinking of trying to increase the amount of melatonin in the lotion through other means.
Art
Back Pain Relief
Thank you so much for your answer about the lotion. Just wondering if you could help with what supplements to take. I'm currently taking:
500 mg Berberine 3x a day.
400mg quercetin 3x a day.plus resveratrol. Not sure dosage. Vitamin C 1000 mg 3-4x a day Lysine1000 mg. 3-4x a day. One multi vitamin per day. minerals, herbal extracts with milk thistle, chaparral, dandelion root, pau de arco and others.
400 mg Oregano tablets. Grape Seed extract and the melatonin as much as I can afford. Have done the castor oil wraps and want to try ivermectin or fenben but not sure which I should try or the dosage. Trying to juice but have an old juicer that doesn't do a great job but better than nothing. Anyway, if you or anyone else has any other ideas I would greatly appreciate hearing them. Thanks again for everything you do!
Melatonin Lotion Feedback
' Art, just a quick update. Last night I had what I thought was a migraine. I applied the lotion and Stopain and by bedtime it had receded quite a bit. By morning it was gone. Usually my migraines last a week. So this was really great! '
Art
Back Pain Relief
The melatonin lotion uses gin and melatonin in an amount that is at least a saturated solution before the lotion is added to the gin and melatonin, so there is no room to add any more melatonin to that mix anyway.
According to the original three friends who use it, it is more effective for them than taking 100 mg of oral melatonin which offered them no pain relief at all for the issues that they reported about, so it must be a fairly potent locally delivered dose they are getting from the lotion, but adding more melatonin to the gin is not likely to be additive.
I take 132 mg of melatonin per day and it offers me no pain relief that I am able to discern, but the lotion absolutely does which tends to suggest that it is reaching very high local levels that my 132 mg of oral melatonin can not!
Art
Back Pain Relief
I have breast cancer and would like to know what dosage the melatonin would be. I was thinking of applying it directly over the breast. I am trying to get up to the 300 mg a day that is supposed to stop the metastes but can't afford the number of pills that would take. Any help would be greatly appreciated and thank you for all your informative advice on this site. God Bless!
Melatonin Lotion Feedback
One of my friends that I wrote about in the original post, Lydia also noticed that applying all the way up the neck to the base of the skull is also working better for any neck pain she still has. She said she thought she was applying it to her whole spine, but had never even thought of going above the hair line, but is happy that she is doing that now.
There are nerves at the top of the spine that travel to the head and face and apparently the melatonin lotion can help calm them when they become inflamed.
Art
Melatonin Lotion Feedback
' Hi Art, I am only taking 1 25mg Losartan (I was taking 50mg) and my bp has been well in the normal range. I've taken it in the a.m. and p.m. and it's running about 122/75. That's a good reading for me.
The weather outside is frightful (as the song goes). It was about 29 last night but warmed up to the 50's today. That usually sends my aches and pains on the increase. I did stay inside today, but did really well. I was surprised especially since I was on my feet a lot last night standing at a ladies golf party and talking to people. Usually that would kill my back. However, I used the cream and stopain 2 times today and have really done well. My neck hasn't bothered me in a couple of days now and my back will give me a little ouchy feeling, but nothing like I would usually expect given the weather. I also have used it on my left shoulder, hip joints and knees. And, yes, any pain I had there seems to have gone away for now. We'll see. I'll keep you informed.
On another note, I was diagnosed with thyroiditis...maybe from the machines they but down my throat from an endoscopy I had done a couple of months ago. It had been kind of an on and off problem with swallowing. It got really bad last Tuesday where just swallowing my saliva was painful. So I decided to try the cream and the Stopain and guess what? There was a huge improvement by the next day. Within 3 days the swelling in my throat has pretty much disappeared. I don't know if there is any correlation, but I thought I would just share that with you.
take care,
She also more recently wrote this to me :
' Art, thanks I'll try that...the muscles of my head get so tight they hurt...
BTW I was having ankle problems and used the lotion and Stopain with good results.'
Art
Back Pain Relief
Back Pain Relief
I just wanted to mention that I used the homeopathic remedy that you are referring to for two friends with spinal stenosis. It cured one friend, but did not help the other. The friend that it did not help had multiple diagnosed spinal issues including cervical spinal stenosis and that may be why it did not help that friend. The friend that it did help had a diagnosis of only lumbar spinal stenosis.
Art
Back Pain Relief
https://homeopathy-allyson.blogspot.com/2020/05/aging-spines-feel-young-again.html
"From Earth Clinic (https://www.earthclinic.com/cures/spinal_stenosis.html#mr):
Spinal Stenosis Cure that absolutely works, never do back surgery, the doctors are not good enough yet and they will ruin your nerves terribly! Dr. Debra Katchen, MD and homeopathic doctor wrote an article “Aging Spines Feel Young Again” (unfortunately, homeopathy.org makes you become a member $ 75 to get into their website for the article but I use this remedy so I put it in my phone. Here it is, dirt cheap, need to do for six months and then I would do it every few years to keep the stenosis away, there is a lady on Youtube who also did it and has a testimonial how great it worked...
Take one tablet of strength 30C HEKLA LAVA pills in a 6 oz glass of distilled or purified water, let it dissolve, put in fridge and daily take 2 teaspoons (am and on preferably) and in addition, take four tablets under your tongue of CALCAREA FLUORICA strength 6X once a day for 6 months. (Amazon, iherb, Swanson, Vitacost to compare prices, there is a company brand Hyland in these small like chapstick containers is pretty popular but other companies have those pills). You will start feeling better about 3 months in but continue for the 6 months. Really, really works!!"
Back Pain Relief
I forgot to ask if you still had a problem with tiredness from the application? If so, how did you work around it?
Art
Back Pain Relief
Thank you for this important feedback on how well the melatonin lotion is working out for you! I am very happy that you are finally finding some long needed relief! As to the physiatrist you saw, I have several words for that person, but I can't post them here.
You've got multiple spinal issues going on and I am glad the lotion is helping you with them. It is worth mentioning that melatonin is also useful for fighting osteoporosis, as I previously discussed here :
https://www.earthclinic.com/cures/osteoporosis-supplements-art-solbrig.html
And here :
https://www.earthclinic.com/cures/melatonin-for-osteoporosis.html
Something else I have found very useful for bulging discs and degenerative disc disease (DDD), I wrote about here :
https://www.earthclinic.com/cures/ddd-art-solbrig.html
It sounds like you are going to be having better days ahead because melatonin can be healing to the body in general and the DDD/HA/Stopain remedy is likely to be additive based on reports on EC and from my friends who have used the combination.
Btw, my friend Lydia, who was one of the three friends that I wrote about, had also used the Salonpas patches and ran into the same sensitivity issue as you after about a few weeks of use and could no longer use them, but she did say that the melatonin lotion was more effective and non-irritating.
The following discusses how melatonin can be beneficial for the spine :
https://www.earthclinic.com/cures/melatonin-spine-health.html
Please keep us posted on your great results using melatonin lotion! Also, please update us on how it works for your shoulder pain. Lydia applies the lotion to her whole spine regularly now and I discussed why that might be a good idea here: https://www.earthclinic.com/cures/melatonin-spine-health.html
Art
Back Pain Relief
★★★★★
Thank you for your response. It has been about a week since I first started applying the melatonin lotion to my lower back twice a day. I decided to apply it to my shoulder as an after thought several days later.
While my shoulder is still causing me pain albeit reduced, I was shocked to wake up this morning with minimal pain in my back. Prior to this I had been applying salon pas lidocaine patches all over my back and shoulders. My skin eventually became hypersensitive to this and I had to be careful not to apply the patches to the same spots on consecutive days. The results I am seeing from the melatonin lotion have been getting better and better with each application. Today was the first time in months that I have been able to get out of bed and function without waiting 3-4 hours for the pain to subside before I could function at all. I am amazed and praying that this is not a fluke.
I would like to clarify why I am applying this lotion, for any of your readers who are wondering if it could possibly help them: I was diagnosed with broad-based disc bulges and spinal canal stenosis and foraminal narrowings in the vertebrae starting in T12-L1 and extending all the way down through L5-S1. There is a severe spinal canal stenosis at L4-5 and L5-S1. I have been in constant pain, unable to sit or lie down comfortably, groaning with every shift in my position. Some days I was unable to walk at all or even take my small dog outside for a short walk. Prior to this I was an very active individual. I spent 3 decades working out in the gym, have my personal trainer's license, spent 1 decade in amateur women's bodybuilding and several years studying tae kwon do. Being so severely restricted in my movements because of back pain has been beyond depressing. I have not been able to continue with chiropractic adjustments because of severe osteoporosis. The physiatrist I saw for help told me that eventually I could expect to be wheelchair-bound and lose the ability to control bowel function, and that the only remedy for pain relief would be spinal fusion, which by the way, he did not recommend. LOL. I don't know anyone who has had relief from their issues after having a spinal fusion, so that was never on the table for me. I understand that pain remedies cannot affect the physical deterioration of the spine, and the doctor's prediction may or may not come to fruition, but the results I am seeing from using this lotion have given me more hope than I have had in a very long time. I am grateful for any relief I can get at this point that allows me to get back to functioning normally. This lotion has been a godsend. I will continue to update you. Thank you for all your posts, Art. I appreciate you.
Melatonin Lotion Feedback
Melatonin Lotion Feedback
Back Pain Relief
Thank you for the feedback on the melatonin lotion! I very much appreciate it! You can try adding more lotion to your mixture to reduce the amount of available melatonin per application and, as my friends did, make sure that you are applying it sparingly. It doesn't seem to take much to be effective and the effectiveness seems to increase with continued applications. You can also try just using less melatonin in your initial mixture.
As far as the tiredness related to the application, I have seen this in some people. It seems that people who are very sensitive to oral melatonin also seem to be more sensitive to topical melatonin. If increasing the lotion content or decreasing the melatonin content doesn't help with the tiredness, about all you can do is try your applications later in the day so the tiredness comes when you would normally expect to start getting tired.
As far as feedback, yes definitely! The more feedback we get on this forum, the better for all of us. You are the first on this forum to give an idea of how it works for you. My friends noticed that the positive effects seem to increase with continued applications. All three are barely finishing their first bottle of lotion.
I have two other friends who started recently and both report positive results so far. Today, a third friend started using it for neck pain that did not respond to borax or the DDD/HA/Stopain remedy, although both of those remedies worked for the desired purposes for her. The neck pain seems to be a separate issue and she said she will let me know later in the week if the lotion is helping her neck issue for which she has no diagnosis.
Thank you again for the important feedback, Sharon!
Art
Back Pain Relief
★★★★★
Melatonin will only partially dissolve in most lotions, the end result is that you will have a significantly weaker mix than what my friends used. Melatonin has high solubility in ethanol and that is the reason that they used it. Do you have a problem with using gin?
Art
Melatonin Lotion Feedback
Since melatonin is both lipophilic and hydrophilic, could one just dissolve the mel powder in their moisturizer (I use tallow) and skip the alcohol step?
Thanks,
Susan
Melatonin Lotion Feedback
I'm excited to hear your results too!
Art
Melatonin Lotion Feedback
★★★★★
I dissolved the melatonin first in the gin in a beaker with the magnetic stirrer. I separately dissolved the capsule of HA in distilled water in another beaker before adding it to the melatonin/gin. Once mixed, I then poured the concoction into an empty glass spray bottle and tested it on my hands.
One spray was a perfect amount for the top of each hand. It absorbed rapidly and left behind silky soft skin.
- 1 gram of melatonin powder
- 1.5 oz of distilled water
- 1.5 oz of gin
- One hyaluronic acid capsule (60 mg per capsule)
- Gram Scale : https://www.amazon.com/gp/product/B07TBJBFRK
- Magnetic Stirrer: https://www.amazon.com/dp/B072K24X5P
- Glass Beaker Set (small): https://www.amazon.com/Borosilicate-Measuring-Set-V-Shaped-Kitchen-Restaurant/dp/B0BC7QZFX6
- Hyaluronic Acid: https://www.amazon.com/gp/product/B0013OUKO8
- Melatonin Powder: https://www.amazon.com/gp/product/B00JV46FFU/
- Gin - local liquor store
I'll update later on pain relief and skin improvement and whether or not the formula clogged the spray nozzle! Thank you, Art! Very excited to try this.
Yes, unfortunately, outside of the US, generally requires a prescription in many places in the world. I find the logic for this restriction unfathomable given the excellent safety profile of melatonin which is safer than ibuprofen, naproxen, acetaminophen or aspirin which they allow you to buy in unlimited amounts and these generally offer little to no other health benefit other than pain relief. Add in the many health benefits that melatonin has shown in humans, animals and plant life and the restriction becomes even more absurd. I mean how does a government organization that is supposed to be operating for your health and safety make such a judgement about something that is so healthful for you?
To give a little perspective, acetaminophen/Tylenol toxicity is the number two cause of liver transplantation worldwide and the number one cause in the US! It is responsible for 56, 000 emergency room visits per year and causes 500 deaths per year, but you can buy all you want from any grocery store.
On the other hand, from 2012 to 2021, there were two deaths in children and these were attributed gummies candy style melatonin that the children ate like they were candy because the parents left them out. So if you take that same 9 year period and estimate that 500 people die per year from acetaminophen, that's 4, 500 deaths compared to 2 for melatonin.
A relevant quote from the article ;
' A study of poison control calls in the U.S. found the number of melatonin poisoning–related calls increased six times from 2012 to 2021. Of these calls, more than 4, 000 teens and children were hospitalized and two died. '
To give a bit more perspective, acetaminophen, ibuprofen, naproxen and aspirin are all NSAIDS. In the US alone, 15, 600 deaths occur per year and 107, 000 hospitalizations due to NSAIDS as discussed here :
A relevant quote from the article :
' One study estimates that NSAIDs — non-steroidal anti-inflammatory drugs used to treat pain and inflammation — are responsible for 107, 000 hospitalizations and 15, 600 deaths a year in the U.S. '
Possible side effects of ibuprofen use
When used incorrectly, especially chronically, negative effects can include:
- Diarrhea.
- Gastrointestinal problems, including bleeding.
- Heart attack.
- Heart failure.
- High blood pressure.
- Kidney damage.
- Liver toxicity.
- Low sodium levels.
- Nausea.
- Stroke.
- Ulcers.
- Upset stomach.'
When you look at this list, melatonin has been shown in studies to help many of these items, not cause them.
This to me says that the people running these government regulatory agencies should reconsider their positions on melatonin requiring a prescription when the named NSAIDS above can be bought with no restrictions at all!
I think the same should apply to borax also as it banned in many areas of the world, yet how many people die form borax in the US each year, where you can buy it in any quantity in any laundry aisle in the country everyday with no restrictions. If you can find the number of people who die from borax consumption each year in the US, please post it because I couldn't find that number. There are words to describe this situation more accurately, but I can't say them here.
Art
Melatonin Lotion Feedback
Melatonin Lotion Feedback
Where to Buy
Melatonin powder is available in one strength, but manufacturers describe using different amounts to equal so many milligrams such as 3 mg or 10 mg. They are basically mentioning the dose they are recommending and sometimes include a scoop for the amount they are recommending.
So any bulk powder melatonin should work. Earth Clinic has posted an easier mix that requires just one, 1/4 teaspoon at level full to make a 3 ounce melatonin lotion mix. You can find that in the original article where it has been added today.
A $20 bag of melatonin powder should contain about 25 grams of melatonin and that should be enough melatonin to make at least 25 mixes of melatonin lotion.
Skip the $200 bag of melatonin. My friends used the bag of melatonin that EC linked to in the article which is around $20.
Art
Where to Buy
Melatonin Lotion Feedback
★★★★★
I have an idea to simplify making the melatonin lotion since you don't use a milligram scale. Make just 3 ounces of lotion at a time instead of 4 ounces in the following way :
- Take your four-ounce jar and add one level full one-quarter measuring teaspoon of melatonin powder into the jar.
- Add one ounce of gin to the melatonin in the jar. Replace the lid and shake well until the gin looks clear again.
- Add 2 ounces of Cetaphil lotion to the jar. Replace the lid and shake until well-mixed.
This is the simplest I could figure out for using measuring teaspoons. The 3 ounces will still last a very long time. Remember that my friends said that they apply sparingly.
Art
Melatonin Lotion Feedback
Your feedback will be very useful since I have not tried it for hip pain yet.
Thank you!
Art
Melatonin Lotion Feedback
Melatonin Lotion Feedback
Oral melatonin at higher dosing had no benefit for my three friends as far as their spinal, muscle and joint pains as all three were already taking oral melatonin. The lotion was able to help them in a way that the oral dosing could not and this is likely because the lotion allows significantly higher local tissue concentrations of melatonin that their higher oral dosing could never achieve as the oral dose is essentially dispersed throughout the body whereas the lotion gives a higher tissue concentration in the specific area where it is applied.
Art
Melatonin Lotion Feedback
Thank you (looking forward to a sucessfull outcome)
Sincerely
Richard
I just now had time to measure out a gram of melatonin powder. This is a very inaccurate way to measure because measuring spoons vary by country and by manufacturer. I have several measuring spoon sets and all of them are different from each other, but this is what I found with one of my sets and using a digital milligram scale. A one quarter teaspoon at level full equaled 760 mg. I added a one eight teaspoon at level full and this brought the total mg up to 1, 120 or 120 mg more than my friends used for their mixes. If you divide the one quarter teaspoon of 760 mg in half, that equals 380 mg which should be very close to one eighth teaspoon. So when you add that 380 mg to the 780 mg, that equals 1, 140 mg. So the 1, 120 mg is close to the 1, 140 mg suggesting that this is about as close as I will be able to get using measiring spoons to get close to a gram. It takes 1000 mg to equal one gram, which is the desired amount of melatonin that my friends used in a 4 ounce mix.
So if your measuring spoons are similar to mine, It will take one level full quarter teaspoon plus a one eight teaspoon that is just shy of being level full to get to the desired one gram or 1000 mg area.
Because this is not an accurate way to measure, I am not recommending that you do this just letting you know what my level full one quarter teaspoon and level full one eight teaspoon weigh on my digital milligram scale when weighing melatonin powder.
Art
Melatonin Lotion Feedback
Melatonin Lotion Feedback
Question for Art please. I usually take 2,500 mcg capsules of Melatonin at night for help sleeping. Do you have any suggestions or advice for using some Melatonin Lotion for neck and shoulder aches?
Thank you. I appreciate your information.
Where to Buy
I didn't actually add any links for ingredients in the article, but I believe this is the link that EC put into the article for melatonin powder :
This bag will be enough for 25 four ounce jars of the mix described in the article.
This is the common lotion that my friends used to make their melatonin lotion :
This bottle will make approximately eight 4 oz. batches of the lotion.
This is the gin that they used that cost under $20 for the bottle at Costco:
https://www.costcuisine.com/post/costco-kirkland-signature-london-dry-gin-review
This bottle will make approximately over 23 of the four ounce mixes. They chose this gin because of the number of listed botanicals (9 botanicals) in it as well as the price.
I am not recommending these three products, just showing what my friends used for their mixes. I would think that similar products would work similarly.
Art
I will ask EC if they can add these other two links to the article.
EC: Thanks, Art. Links added to the bottom of the article!
Where to Buy
I noted this in the links above --- maybe it was a later addition?
Am doing research for my brother and a couple of friends, and maybe for myself before too long since 69 y/o knees feeling the stresses now.
Where to Buy Melatonin Powder
Bulk Supplements sells a large bag of pure melatonin powder reasonably priced.
Melatonin Powder Bulk Supplements - $18.96 for 25 grams - 8,333 servings
Melatonin Lotion Feedback
I am only reporting the mix that my friends found useful for their issues, but this is not carved in stone. If you have a lotion that you feel is safer, please try it and let us know how it works for you as I am sure others will want to know also.
Art
Melatonin Lotion Feedback
Melatonin Lotion Feedback
Where to Buy
I called a Homeopathic Pharmacy but they did not have it, as I bought two other items related to Earth Clinic's email. I am really interested to know where the Pure Melatonin Powder and the Cetaphil Moisurizing Lotion could be bought as there was no note of this on the link. Thanks.
Melatonin Lotion Feedback
Since you feel Cetaphil lotion is not too bad, the gin is essentially diluting the lotion which means that you are getting less of the bad in the final mix, but if you have a preference for another safer lotion in place of the Cetaphil Lotion, you can try that and let us know how it works for you.
The Cetaphil Moisturizing Lotion is readily available, not too expensive and many people are already familiar with it.
Regarding the use of gin, it is because of the juniper berry and botanical content which imparts a fresh scent and may offer other benefit imo. Here is a link discussing a few of those important benefits :
https://www.healthline.com/nutrition/juniper-berries
Here are some relevant quotes from the article :
' Juniper berries are high in vitamin C, flavonoid antioxidants, monoterpenes, and coumarins, all of which may offer various health benefits.'
' Juniper berries contain essential oils and flavonoids that offer antioxidant and anti-inflammatory effects.'
' Some rodent studies indicate that juniper berry extract may improve high blood sugar levels, though research in humans is lacking.'
' Some animal research suggests that juniper berry extract may improve heart disease risk factors, but studies in humans are lacking. '
' Test-tube and animal studies indicate that juniper berry extract provides strong antibacterial and antifungal effects. However, human studies are needed to confirm these benefits.'
Again, for me the importance is in the effects of the lotion as unobtrusively as possible as well as the ease with which it can be made by the majority of people at home and not so much in the fine tuning to personal tastes.
If you do try VCO or another lotion, please come back and let us know how it works for you.
Art
Melatonin Lotion Feedback
Thank you for saying so!
Actually I consider melatonin powder relatively inexpensive as it applies to this lotion which only requires one gram per four ounces of lotion at a cost of roughly one dollar of melatonin per mix which does not seem like much for an active component imo.
Usage rate will vary by the amount being applied and the area being covered. If you are only applying to the neck or lower back, the lotion should be fairly long lasting as my friends mentioned in their answers to my questions. All three reported applying sparingly which would also add to the lifespan of each jar.
None of the three have used up their first four ounce jar yet. Lydia is the one I consider to be using the most as she is using it on her lower back, neck, shoulders and muscles that are impacted by her disease and she is still using her first jar.
Very importantly, all three are finding significant benefit with their lotion with only two applications per day with benefit beyond what Stopain was able to offer them with regular use. Melatonin has a very good safety profile. All three have told me they enjoy the simplicity of making this lotion themselves at home.
Art
Melatonin Lotion Feedback
1. As regards the safety of Cetaphil lotion, I chose it for its longevity as it has been around for many many years in thousands of users which should have well exposed safety issues with it. I am not saying it is the only lotion that can be used, but it is readily available online and in stores. I think most lotions will also work if an individual has a preference.
2. Coconut oil is a natural product that has a known safety profile, but I would never have considered it because many people do not like the smell of coconut oil and some people already consider Cetaphil to have a less than desirable smell, even though the fragrance is extremely light to me. Some people do not like the oily feel of coconut oil until it is absorbed fully. If you try a coconut oil mix, let us know how it works for you.
3. Vodka will work similarly to the gin. I chose gin because of the juniper berry content and botanical content and it seems to have a very mild alcohol smell that essentially disappears once the mix is complete.
Art
Melatonin Lotion Feedback
Melatonin Lotion Feedback
★★★★★
★★★★★
1. Is it safe to use Cetaphil Moisturizing Lotion long-term, given its chemical make-up?
2. Would using virgin coconut oil be a safer alternative to Cetaphil?
3. Since we use vodka in place of alcohol, would substituting vodka for the gin give the same positive results?
Thanks in advance for your help!