The comments below reflect the personal experiences and opinions of readers and do not represent medical advice or the views of this website. The information shared has not been evaluated by the FDA and is not intended to diagnose, treat, or prevent any disease or health condition. Always consult a qualified healthcare professional for medical concerns.
Grapefruit Seed Extract
Posted by Anne (Austin, TX) on 01/25/2022
★☆☆☆☆
Grapefruit Seed Extract
Posted by lisa (ny) on 11/16/2021
You need to add salt!!!
Grapefruit Seed Extract
Posted by Erkin (Germany) on 06/11/2020
Art, Thank you very much for your comment. I already heard of biofilms but never focused on that. I will give it a try and report if I see any effects.
Grapefruit Seed Extract
Posted by Art (California) on 06/10/2020 2325 posts
★★★★★
Erkin,
One feature of long term sinusitis is that biofilms can form to protect whatever pathogen('s) are present. Xylitol has biofilm busting characteristics as does colloidal silver. There is a commercial sinus spray that contains xylitol called "Xlear" that I have bought and is available on amazon : I can use the colloidal silver (AgNPs) in a neti pot, but not at the same time as the Xlear because the saline portion of Xlear may cause the colloidal silver to break down if the colloidal silver is not capped. So, for myself, I might use Xlear in the morning and colloidal silver in a neti pot with 5% to 10% xylitol dissolved in the colloidal silver in the afternoon and then Xlear in the evening and repeat each day until the biofilms are destroyed and the pathogen('s) eradicated.
A third option I might also try for myself is to skip the Xlear and just use the colloidal silver + 5% to 10% xylitol in my neti pot as needed.In my experience, I have also found that the xylitol has helped to reduce the sting of 20 ppm colloidal silver from the neti pot and I only mix enough for one use at a time and do not store any of the mix unless I will be using it the same day that I made it.
https://pubmed.ncbi.nlm.nih.gov/27394715/
Silver nanoparticles have biofilm busting qualities.
https://pubmed.ncbi.nlm.nih.gov/24432308/?from_term=silver+nanoparticles+biofilms&from_filter=simsearch1.fha&from_filter=simsearch2.ffrft&from_filter=simsearch3.fft&from_size=20&from_pos=1
As long as the biofilm(s) are present, the pathogen's are fairly well protected and resistant to most attacks against them so breaking them down is important. Art
Grapefruit Seed Extract
Posted by Erkin (Germany) on 06/10/2020
★☆☆☆☆
I bought grapefruit seed extract (one that is recommended in blogs in Germany) because of positive comments here and I am using it now for 1 week. I have a chronic sinusitis for around 20 years and I have been operated three times on my sinuses. Unluckily, I couldn't see any benefit of the grapefruit seed extract nor for my sinusitis neither for anything else. I drink it with water (20 drops in 1 glass 2 times per day). Since three days I use it also as nose spray. I mixed 10 drops in 20 ml water and spray it three times a day. But using it as nose spray irritated my nose and I feel more bad than before using it. I will stop using it.
Grapefruit Seed Extract
Posted by Marci (Central Florida) on 02/28/2017
The 10 drops in 5 ounces of water is what you drink or use as a nasal rinse? I had a viral sinus infection about 5 months ago and at least 50% of my smell and taste are gone. I started the saline rinses but have not noticed much differences yet (only 4 days consecutively). I made my own nasal spray with GSE, and have been using it once a day for months, but guess I need to step it up.
Grapefruit Seed Extract
Posted by Kimberly (Birmingham, Al ) on 02/14/2016
What is the maximum daily usage you would recommend one can use the 4 drops of Grapefruit Seed Extract Liquid in saline solution. In other words, how many times can I rinse with the saline, using the proper ration of saline to the extract liquid?
Grapefruit Seed Extract
Posted by Sl (Ky, US) on 02/08/2015
★★★★★
I have been using grapefruit seed extract 10 drops in 5 oz water plus 1 packet of a sugar alternative for sinus infection. It is a miracle! I do this 3 x day. Also using a nasal spray plus. So glad I found this works! Next time I think I can avoid Dr. visit.
Grapefruit Seed Extract
Posted by Faith (Pdx) on 11/13/2014
Mayo Clinic states that 90 percent sinus infections are fungal.
Grapefruit Seed Extract
Posted by Heather (Santa Monica) on 04/16/2014
★★★★★
Yep, grapefruit seed extract is my go to remedy for sinus infections. I've tried in my neti pot, but it's too strong. I usually take GFSE drops internally (about 10 drops 3 times a day) but also use sea salt and peroxide in my neti pot to irrigate the sinuses.
Grapefruit Seed Extract
Posted by Sue M. (Worden, Il, Usa) on 01/10/2013
Hi John... I have been using the GSE for the past month... Mostly the 2 oz of distilled water with 3 to 4 drops of the GSE solution for nose drops. First thing of a morning, I use about 1/3 dropperful for each nostril. After slightly tilting my head back for this (naturally.. lol), I hold my nose and then bend from the waist and have my head down by my knees. Then I shift to the right and then the left and do this about 3 times. When I come back up, I sniff a couple of times (not hard) and then blow my nose. Surpringing what can come out... :( This helps to keep my head clear all day and on a prevention measure during this flu/sinus season, I take 10 drops in about 4c. of water and drink during the day.
The directions on my bottle say to mix 10 drops into 5oz of water or juice 1 to 3 times daily, with or without meals.
Grapefruit Seed Extract
Posted by John (Leesburg, Va Usa) on 01/10/2013
Does one take the GSE orally or by nose or both?
Grapefruit Seed Extract
Posted by Kristin (Albuquerque, New Mexico/USA) on 12/02/2012
After fighting a sinus infection for a full year with 5 rounds of antibiotics I finally sought out a natural cure. Resigned to being constantly stuffy and 'nasal' sounding, I was skeptical about these treatments.
After reading this and other sites I put myself on a strict regime of the following:
- Apple cider vinegar (2 Tbls. Mixed in water or juice)- NOT tasty; 3 times a day
- 1000 mg Vit C a day
- Oregano oil (tablets) as directed
- Saline nasal rinse (I use Neil Med bottle/mix) with warm water and 10 drops Grapefruit seed extract; 2 times a day (I started at 5 drops and worked up to 10 to avoid potential burning others described)
My results were not as immediate, however I'm now on day three and for the first time in months my sinus pressure is down, I have drainage (it's finally breaking up in there!), and that stuffy feeling is going away!
After a year of infection built up, I'm not suprised it's taking more time but I believe it's working.
Grapefruit Seed Extract
Posted by Randall (Sioux City, Iowa) on 10/31/2012
★★★★★
FOUR MONTHS OF SINUSITIS! TOTALLY MISERABLE! Two rounds(10 days each) of amoxicillin. Nothing. Still having one nostril closed off almost 24/7 and the other half open. Sleep was almost impossible and I was just miserable. I started to Google to find any other way to help. Warm compresses, hot showers, and more antibiotics.
Then I saw GSE. Ordered it and that was the miracle that I was looking for. Took a 2 ounce nasal spray bottle left over(couldn't live without the over the counter spray that at the end only kept my nose open for less than a hour)cleaned it out and put 2 ounces of saline solution and 3 drops of GSE in it. DAY ONE: Took eight ounces of orange juice with 15 drops of GSE concentrate three time a day(45 drops a day total). I then sprayed my homemade GSE nasal mix in my nose 4 times a day with 2 sprays in each nostril each time. By morning two I stared to blow my nose and sorry this may sound gross but the green/yellow mucus was thinning and turning clear. I could not believe it! I woke up with only a small headache for the first time in months and I could breath a little better.
DAY THREE: UNBELIEVABLE! I could breath out of both nostrils! Not completely but well over 50% better! Pressure and pain was less than half. All the antibiotics and hot showers for the last 4 months had done nothing close to the 2 full days of GSE. To make my story short and happy within 6 days of continuing the GSE treatment I was cured! YES CURED! People say that GSE only works because it has some synthetic stuff in it. Why do I care. IT WORKS and no side effects! And the cost is crazy! CHEAP! CHEAP! CHEAP! I will never be without it. I will always keep in touch with my Dr. But GSE will almost always be my first course of action for any cold or sinus problems! You have to try it. IT WORKS MIRACLES!
Grapefruit Seed Extract
Posted by Rachel W (San Francisco, Ca, Usa) on 09/18/2012
★★★☆☆BETTER BUT WITH SIDE EFFECTS
I get severe sinus infections at least once a year, either from seasonal changes or developing it when I catch a mild cold from someone.
This time I had a small cough that lasted a week before the infection progressed to my nose (just in time for work on Monday, ugh).
I've previously used saline solution with my neti pot with some success, but only if I do it early enough. When my sinuses get worse it only irritates it even more and causes more swelling. Even Apple Cider Vinegar has only temporary effects on me.
A friend recommended GSE in my netipot and voila! Instant results with just a couple drops of it in the water. It completely drained my nose! It was expensive but very well worth it. It's my first day using it but I plan on doing it every day until it goes away. I'm also adding it to my water to drink. I did notice that my sense of smell/taste were completely gone, which I'm hoping is only temorary until my sinuses are normal again. However, I'd much rather try this than any over the counter colored chemicals that make me drowsy!
Grapefruit Seed Extract
Posted by Mlove (Honolulu, Hi) on 07/17/2012
★★★★★
I just wanted to say that I have been taking grapefruit extract in tablet form for years whenever I get a cold or sinus infection. I take 2 little tablets three times a day for about a week and on the third day, I always feel better. Colds do not go into sinus infections if I take it and if I do get a sinus infection (like I did recently from swimming in the ocean), it goes away within a couple of days when I take the tablets. If I don't tke them, I stay miserable. I had a naturalpathic doctor tell me it was okay to take them for as long as a month at a time, but I never need to. They always make me feel better, so I take them anytime I feel a little under the weather and it always works. My husband does the same thing and it works for him too. The tablets are small and easy to get down. No bad side effects for us, only good effects.
Grapefruit Seed Extract
Posted by Sarah (Lebanon, Nh) on 06/27/2012
★★★★★
I was diagnosed with nasal polyps a month ago. I had chronic sinusitis (not a runny nose, just often stuffed up and a poor sense of smell) which never really bothered me until one of my nostrils became constatntly plugged. First let me say that there is a lot of scary stuff on the internet when you're looking for health information. Sure this condition is annoying, but life is still pretty good!
I went to the ENT, was diagnosed, and he gave me 2 weeks of prednisone, and an antibiotic. Steroids are terrible for you, but they also shrunk the polyp and brought back my breathing, and sense of smell! All the while I wondered what would happen to my nose once I was off the steroids.
By the time I was done with prednisone my nose was not 100%, but it was much improved. My constantly plugged nostril was now open 60% of the time. I then started a steroid nose spray (which supposedly have fewer side effects) to keep things open.
Things seemed pretty stable for a week, and I decided to try some of the homeopathic remedies to see what effects they had. I got really brave, and put two little drops of GSE into my neti pot.
I did my third GSE neti wash tonight, and it seems to be making a difference! My "bad" nostril is open almost all of the time now, and still seems to be on the upswing. I will say this - the GSE certainly isn't hurting anything, and I distinctly feel that it is improving my condition.
I'll write more if anything drastically changes. I got an allergy test which came back totally negative, so what's causing the inflammation in my nose is sort of a mystery. I guess the theory with GSE is that if I have a low level fungal infection, or perhaps an over reaction to normal fungus in the air, the GSE and its potent antifungal properties helps reduce my inflammation. Hmm. as of now, I think I buy it.
Grapefruit Seed Extract
Posted by Kayla (Los Angeles, Ca) on 04/18/2012
★★★★★
I went to the dentist because I thought I had a cavity, because my tooth felt hot/cold sensitive. The dentist said it was not a cavity but a sinus infection that had caused the root of my tooth to become swollen we looked at the xIrays and I was stunned, at how stuffy my sinus appeared on the x-ray. I had no headache, no pressure, no was I stuffy a slight runny nose, really nothing except the tooth issue. I have suffered from dry eyes, red itchy eyes and crazy itchy tear ducts. So I used a neti pot with purifed water, three drops of Grapefruit Seed Extract and sea salt. My nose and eyes began clearing up within hours and I found the itchy eyes and the itchy tear ducts stopped immediately.
Grapefruit Seed Extract
Posted by Timh (Louisville, Ky, Usa) on 03/25/2012 2048 posts
Sarah, I have had good results w/ Liquid Grapefruitseed Extract Concentrate mixed w/ vegetable oil for fungal infection, but nothing noted for viral. As for the interactions, did you mean Grapefruitseed or Grapefruit??? because there appears to be very little or no Naringin in the seed as compared to the fruit. There is a discussion on this somewhere on E.C.
Grapefruit Seed Extract
Posted by Sarah (London, England) on 03/24/2012
★★★★★
Grapefruit seed extract for chronic sinus infection: Cannot recommend it enough! Knocked out the 3 month sinus infection that nearly killed me (docs threw useless rounds of antibiotics at it) and reduces the incidence of viruses! I have
not had a single sinus infection since I started taking it a year ago and my colds etc arent as bad: 12 drops in a glass of water 3 times a day (Ive cut it down to twice a day now and Im still just fine) Tastes nasty but MAGIC STUFF!
Taking more does no harm and you are meant to take it on an empty stomach, You should also take it at a different time to some meds such as magnesium, fexofenadine antihistamine and monoamine inhibitors (antidepressants I think) or it reduces their effectiveness - grapefruit actually interacts with a few meds so do your research!
As for me, I have TERRIBLE sinus issues from a life of severe allergies (hayfever) that left me with regular infections for all of my young life (I suppose thatd be all my life as im only 24) but since I started GSE I havent had another sinus infection since and it more or less saved my life It also reduces viruses :) (Oil of Oregano is good for this too)
Grapefruit Seed Extract
Posted by Elizabeth (Oceanside, Ca) on 01/31/2012
I agree with Emersmask from Media, Pa, Usa. I had the same reaction when I used the GSE in the neti pot as well as ACV in the neti pot (different occasions). Severe symptoms: pain, sneezing, increased inflammation. This went on for hours.
Grapefruit Seed Extract
Posted by Nathan (San Rafael, California) on 12/29/2011
I found that GSE as a nasal spray has little effect. A nasal rinse works best Then drink a 10 oz glass of orange juice with at least 15 drops of GSE 3 times a day. The orange juice takes away the bitterness of the GSE. I am presently taking 30 drops in my OJ 4 times a day. I'm finding this to have better results than the antibiotics prescribed by my doctor. I take GSE where ever I travel. It kills parasites, viruses, bacteria and fungus. If I feel a cold or flu coming on. 30 drops immediatly usually does the trick.
Grapefruit Seed Extract
Posted by P (Middle Of, Fl) on 12/21/2011
I use the grapefruit seed extract
tablets with great success, I've taken up to 3 at a time no problem, but then later on noticed heart burn so I needed to reduce again and no heartburn!
However I've tried sea salt for a cold one day because I waited too long to attend myself and needed a quick fix, and the minute it hit my belly I felt the difference...my nose stop running, stop coughing & fever went away thus aches & pain!
The reason why I mentioned this is because I felt my sinuses declogging, I even heard it making noise, so perhaps it may work for you!
This is what I did:
1 teaspoon of sea salt
1 glass of water
and really try to drink it down! Yuk, but worth it!
Thanks to the good people of EC I read the water cure websites and they claim 1/8 of a teaspoon of salt dissolved on your tongue and drink a glass of water and dont babysit the glass of water may do the trick; but keep in mind its less salt therfor you ought to do it more times!
Also half your weight of water in ounces divided into six times a day will do the trick among other tricks!
example; if you weigh 200 pounds drink 100 ounces of water daily! But not all at once! Its like drinking 8-9 bottles of 24oz of water a day will keep you disease free!
Grapefruit Seed Extract
Posted by Francisca (Zug, Zug, Switzerland) on 12/21/2011
Hi, you must have a different kind of GSE than we have here in Europe! I have tried two brands so far but none of them burns or anything of the kind. Usually I take 15 drops in a glass of water 3 times a day and I have never noticed any side effects. Both times I have taken it I take a bottle and then stop for a few months. I have to say that I don't notice any major changes other than once, when I had a bad cold and my nose was running the whole time the cold was gone within a couple of hours.
Grapefruit Seed Extract
Posted by Emersmask (Media, Pa, Usa) on 12/20/2011
I have had a very strong and rather unfortunate reaction to the GSE. I have used it before with some success, and after a chronic season of sinusitis, I attempted another go today. While it is not the most comfortable, soothing remedy in the world, I was not prepared for the extent of the irritation and pain I experienced this time around. Pain--awful--burning that persists four hours later, and the chronic inflammation has gotten much worse.
6 hours later--the problems persist.
The worst part is that I have absolutely NO sense of smell. I'm praying that this in particular resolves very soon.
Either I used too much, or developed a sensitivity. I followed the instructions very closely, diluting a few drops in 8 oz of water, but it is possible I mis-counted.
In any event, this can be effective but I highly suggest you start with a very small dose--2 drops or less--and work your way up to where it does not burn.
And if anyone has this same experience or any insight as to if/when my smell sense will return, please share!
Grapefruit Seed Extract
Posted by Jane (Andover, Ma) on 04/02/2011
You are supposed to use 1/4 tsp fine salt in a Neti Pot... Not 1/2 tsp. Maybe that us why you felt burning? Salt in a wound? Try less salt, and body temp warm water. I hope it's better.
Grapefruit Seed Extract
Posted by Jamie (Lake Worth, Fl) on 03/10/2011
I also had a great experience with grapefruit seed extract. At work a girl came in sick (thanks pal) sore throat, very bad, and flu type ailments. Sure enough we all got it, my throat was not just sore, it felt like it was swollen. Maybe glands, my ears hurt down into my neck. After 2 days of getting worse, I started grapefruit seed extract. 10 drops 4 times a day, after the first day I felt a little better. I put it in warm water and drank it. This was very soothing to the throat. After two full days I was almost all better, I did continue four days, six days total
My coworkers who just let it pass naturally were sick for two weeks, some longer. I really think this stuff helped me, next time I will use it at the onset of an illness.
Grapefruit Seed Extract
Posted by Stacey (Reading, Pa) on 03/09/2011
★★★★★
Amazing! I regularly suffer from sinus infections and had been using apple cider vinegar in warm water to treat it. This time it was just not doing the trick. I tried 4 drops of grapefruit seed extract in my neti pot this evening, and just 3 hours later I am feeling the release of pressure and drainage. I have my fingers crossed for the futher improvement over the next few days with continued treatment - but already I am impressed!
Grapefruit Seed Extract
Posted by Libby (Riverside , Florida ) on 02/19/2011
★★★★★
I frequently use gse during the winter months as a general precaution against several infections , but especially from sinus problems. Every year in January to March my sinuses give me problems. I am 54, female and hate sniffling as it embarrasses me and probably aggravates anyone near me. I also worry about spreading it.
The gse keeps me healthy IF I remember to begin it about two weeks prior to mid-December.
It is bitter, yes, but that it a minor consideration compared to spreading infection to others just because I could and feel lazy. That is plainly evil to spread disease just because I don't feel like placing a few drops into my daily water supply everyday. And so I use it and so my health is stronger in winter than it was when I was younger and careless.
Grapefruit Seed Extract
Posted by Robin (Westhampton, Ny, Usa) on 01/28/2011
★★★★★
I've had a sinus headache for over 2 months with no nasal congestion and no mucus (It actually took me 2 months to figure out it was even a sinus problem at all). Wanting to avoid antibiotics, I tried the Neti pot for the first time ever, using a mixture of salt and colloidal silver. After 5 days of this at 2-3 rinses per day, I had few/no results and not even a runny nose. I still had severe headaches and facial pain in my cheeks and upper jaw.
After reading this site, I tried Grapefruit Seed Extract. Dose 1 opened up the flood gates! I feel THAT strongly about it that I didn't want to wait until tomorrow for Dose 2 to write about it here. I used 7 drops in the saline solution but diluted it half way through because it was too strong to handle.
Grapefruit Seed Extract
Posted by Stefiec (San Diego, Ca, Usa) on 07/12/2010
Does anyone know or have you tried putting GSE in a sinus irrigation solution for fungal infections?
Grapefruit Seed Extract
Posted by Elizabeth (Springfield, Pa) on 05/30/2010
I had the same reaction, however, after approximately 5-6 hours, I noticed the release of pressure. Perhaps you put too many drops in (I know I did...didn't have glasses on) and that's why the sudden headache etc. I've continued once a day with 4 drops plus saline in the neti pot. Blow my nose and all is well! I hope this helps.
Grapefruit Seed Extract
Posted by Mike (Belgrade, Serbia) on 05/24/2010
When I made my grapefruit seed extract rinse with water and salt I got a severe headache and sinus pressure, there was a lot of mucus and my sinuses congested even more. Should I continue to do this?
Grapefruit Seed Extract
Posted by Elizabeth (Springfield, Pa, Usa) on 05/21/2010
★★★★★
After reading your website,I have tried the Grapefruit Seed Extract (5 drops) in my neti pot along with the normal saline. I was on my 3rd round of antibiotics (I'm allergic to many)for sinus infection. I've had headaches for 2-3 months...every day. The crown of my head, base of my skull, but the worst was when I bent over. I thought my forehead would burst.
After the 1st round of the neti/GSE my nose ran for hours and I just kept sneezing. After about 3 hours, I noticed the left side was opened up. It took awhile longer for the right side, and, I'm still waiting for my right ear to pop. I just finished my 3rd neti(which I've always done daily, so, I know it was the GSE that helped) and I can't believe the difference in 24 hrs. This AM was the first morning in MONTHS that I woke up with no headache. I didn't even have to take 1 aspirin! Everything from my nose was clear...just huge amounts. I can't thank everyone enough.
Grapefruit Seed Extract
Posted by Ana (New York, New York) on 04/27/2010
Hi, I've had a sinus infection (so I think),as I only feel pressure but no mucus, and I've been to 2 doctors a this point and both have been prescribing antibiotics for sinus infection.
Anyway, figured I'd try the grapefruit seed extract to try to relieve some pressure to get some relief. I mixed 4 drops in 8oz of water with 1/2 tsp of salt and put into neti pot. As soon as the mixture hit my nasal passages, I felt a strong burning /stinging feeling and immediate pain in my face & head, as if the pressure was getting worse. I tried a couple more times and felt the same thing, so I stopped and wanted to get feedback first before I continue. Is this normal, the burning/sting? Does it feel worse better it gets better (regarding the pressure)? Thanks.
Grapefruit Seed Extract
Posted by Ray-ray (East Northport, New York) on 02/06/2010
★★★★★
I tried using Grapfuit Seed Extract for a sinus infection. 3 drops in 5 oz. of warm water. Eye Dropper full with head back, then tilt head forward, between legs. Adding a couple shakes of Sea Salt takes away the intense pain of water introduced to the sinus cavity by 98%.
Grapefruit Seed Extract
Posted by Rjforshort (Dover, Oh, United States) on 12/23/2009
★★★★★
Grapefruit seed extract nasal wash cured sinus infection
On sign of a sinus infection, I did a 2 cup nasal cleanse (with the nasal syringe) using 2 cups of water, 1/2 tsp salt and 8 drops grapefruit seed extract. I experienced an immediate 'stuffing up' but by morning was symptom free. I repeated cleanse before I went to work and have had no problems since! Worked great!
Grapefruit Seed Extract
Posted by Janet (Alexandria, La, United States) on 11/20/2009
★★★★★
Instead of adding GSE to your saline, purchase the a nasal spray with Grapefruit Seed Extract. It has the correct proportions, and does not sting. It worked for my sinus infection, and I have since bought a bottle for each of my grown children. I could only find it at health food stores out-of-town, so I recommend calling first, because 1 out of 5 stores might have it. Just ask if they have nasal spray with GSE, and stress that you don't mean GRAPE, but GRAPEFRUIT.
Grapefruit Seed Extract
Posted by Laura Coleman (Stroud, Oklahoma) on 11/19/2009
have had sinus infection 20 years every 2 month on antibotica i am now immune to them and on steriods i take toprol for heart palpations. it a blood preasure med. is it ok to use the grapefruit seed extract in my saline solution? I got to get off antibotica need help with natural remedies. help please
Grapefruit Seed Extract
Posted by Diane (Kitchener, Ontario) on 11/19/2009
To Cathy from Homer Geo. How much grapefruit extract would you use in an eight oz. water bottle? I would like to try this cure. thanks, diane
