Guaifenesin
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| Modified on Dec 27, 2021
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Commonly used to treat coughs and congestion, guaifenesin has a variety of other applications as well. A derivative of the guaiac tree, guaifenesin or its generic versions were used by the Native Americans. In any case, the current drug was approved for use by the Food and Drug Administration in 1952 and has gained popularity as a treatment option since then.

What is Guaifenesin?

Guaifenesin is a common drug that belongs to the family of expectorants. As such, this medication functions to thin mucus in the body, typically the throat and nasal passages, to relieve congestion and other adverse health conditions.

Typically sold as a pill or syrup, guaifenesin is a readily available product. It can be purchased under such brand names as Guai-Aid, GuaiLife, Ethex 208, Mumibid, Mucinex and Robitussin. It is also found in a variety of other over-the-counter congestion remedies and is typically combined with dextromethorphan, pseudoephedrine and/or acetaminophen.

Health Benefits of Guaifenesin

As an active expectorant, guaifenesin functions to thin the mucus in the body. It also works to loosen mucus, clear congestion and make breathing easier. These effects have a number of positive health benefits, making it an effective treatment for a variety of conditions.

Most commonly used to treat coughs and congestion, guaifenesin is effective for treating such conditions as the common cold, bronchitis and other breathing issues. As it does thin and loosen mucus, it can also be used to treat infertility. Taken during ovulation, the medication helps increase cervical mucus also increasing the chance that sperm will be able to reach the egg for fertilization.

As with any medication, care must be taken regarding appropriate dosing; however, when taken in proper amounts, guaifenesin is a safe, effective medication. While traditionally used for treating colds and coughs, the medication has other effective purposes as well.

The comments below reflect the personal experiences and opinions of readers and do not represent medical advice or the views of this website. The information shared has not been evaluated by the FDA and is not intended to diagnose, treat, or prevent any disease or health condition. Always consult a qualified healthcare professional for medical concerns.
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Infertility

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Posted by Pat (St. Louis, MO) on 05/11/2008
 ★★★★★

I used Guaifenesin twice to get pregnant after trying for five years. Take your temp every morning. Determine your ovulation schedule. Take Robetussin like the label suggests beginning a few days before ovulation begins and continuing for 4-5 days. It will increase cervical mucus thus increasing the chances the little sperm will swim well! Worked for me!

Replied by Joyce
(Joelton, TN)
05/13/2008
490 posts

Hello Pat, Yea! To all having infertility problems, Please notice. Glad to know that Robitussin is effective for something. I never found it to be as effective as apple cider vinegar & honey for coughs/colds!

Laryngo Phageal Reflux

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Posted by Michele (Los Angeles) on 01/31/2007
 ★☆☆☆☆

I tried guaifenesin (Mucinex)for several weeks because I always had a big clog of mucus low in my throat. It didn't do a thing. Turns out, the ENT suspects I have larygophageal reflux disease. He prescribed Aciphex to see if that will work. I am planning to try some of the remedies on this site first to see if I can deal with this naturally instead of pumping PPIs into my system.

Mucus Conditions

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Posted by Brian (Newark, OH) on 05/27/2006
 ★★★★★

Guaifenesin treats congestion, cold, flu, bronchitis, sinus infections, and may increase chances of pregnancy (obviously not the case for males).

Guaifenesin, available in many OTC cough syrups (tussin) is also available in tablets (mucinex) or available in generic form from many online pharmacies or health-food stores. The suggested dose is 400 - 1200 mg no more than twice daily. Guaifenesin is an expectorant -- so, take it with PLENTY of water. It thins the mucous membranes in the body -- NOT just the lungs or throat, but the ENTIRE (ENTIRE) body. you'll probably cough a bit more than usual for the first couple days -- that's GOOD -- you're getting rid of all the extra CRAP that shouldn't be there, in the first place. I have Asthma and Allergies (as well as a chronic sinus infection) I take loratadine, advair, singulair, benadryl, and albuterol. They work -- a little -- all together . . . but if I miss my guaifenesin -- I can definitely tell. It's rumored that it's also a useful remedy for CFS. Be careful, though -- guaifenesin can cause an increase in blood pressure -- so take it with PLENTY ( I cannot stress that enough ) PLENTY!!! of water!

Replied by Teri In T Town
(Tacoma, Wa, Usa)
08/11/2011

I used to get a post nasal drip that caused me to cough forever after a cold and it seemed as if I coughed all winter every winter. Doctors tried a number of different medications over the years without success. Gauifenesen works, and I suffered no side effects, although it does take a couple of weeks of using it, most likely because coughing becomes and involuntary response.

I have since worked to correct my PH and I keep it alkaline (see Ted' s posts on this) and I now get a cold only when I am under a great deal of stress. The alkaline PH prevents the conditions that cause mucus because it is an unfriendly environment for viruses.

Replied by Nisha77
(Devon Uk, Uk)
09/14/2012

pl. Anybody can tell me, from where I can buy GUAIFENESIN in uk. I could not find in any health shops. Is there anyother generic name u know, pl. help. Regards.

Replied by Lisa
(Thousand Oaks, Ca, Usa)
09/14/2012

Hi Nisha77, Guaifenesin can be found in Mucinex and I believe Robitussin. I think those are available in the UK. Hope this helps, Lisa

Replied by Robyn
(Melbourne, Australia.)
09/14/2012

Lisa, you can get it at iherb. The real stuff without all the other stuff in robitusson

Replied by Paul
(Uk)
07/11/2016

The post doesn't give the details of whether it is slow or fast release and the dosage of the tablets?

Replied by Carmel
(Essex UK)
12/27/2021

I'd like to hear from anyone who tried Guaifenesin for CFS, fibromyalgia etc. I understand there is a protocol run by a doctor in USA in his own clinic, and many people have attested to being cured of fibro or cfs using this. If you have any experiences of it - good or bad - please get in touch with me as I have fibro and cfs and am considering taking this. Have tried other things. I also think it depends on what type of fibro you have and why you have it. Many thanks and happy new year.



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