Previously I had stated that when it comes to Covid-19, the type of melatonin should not be an issue, but Dr. Neel had stated that he was using the type of melatonin that dissolves in the mouth or under the tongue (sublingual).
I thought the only significance of that type was that he felt it would be possible to give to patients already on a ventilator and that was it, but this recent report suggests that there may be more to sublingual melatonin than that! Other sublingual supplements are often said to have better bioavailability in their sublingual forms over regular capsules or pills. Perhaps this is also true for melatonin in its sublingual form? Melatonin on its own has poor bioavailability. Roughly, oral melatonin only offers a maximum of 15% bioavailability at best. So this offers some creedence that even a small increase in bioavailability may have significant ramifications when it comes to melatonin?
Given that information, the following report from a Covid-19/Melatonin patient makes a little more sense and I may need to rethink the use of sublingual melatonin on the chance that it is better absorbed by the human body???
https://devinenews.com/family-of-8-hit-hard-by-coronavirus/
Perhaps type of melatonin does matter??? Since I have been taking melatonin in the capsule form, I may have to get a bottle of sublingual melatonin to see if I respond differently to it? This may take a little bit of time since I have other experiments already in my queue.
Art
Melatonin
Thank you for saying so! I know you are probably already aware of the following, but I am putting it in for others who may not be. COPD is common, so it is worth putting this info up. Some people refer to it as emphysema, but that is an older term and COPD seems more common now as a blanket term. There are some similarities with chronic bronchitis.I'm not sure about the H2O2 for COPD simply for lack of studies to add confirmation to the anecdotal evidence, but the anecdotal evidence is compelling.
In COPD patients who are stable, the amount of H2O2 in the exhaled air is approximately 7 times that of normal controls while patients who are in an exacerbated state are almost 3 times higher than stable patients and about 21 times higher than control patients.
So H2O2 inhalation will add to these already significantly elevated H2O2 levels. This brief abstract discusses H2O2 exhalation levels in people with COPD:
https://www.atsjournals.org/doi/10.1164/ajrccm.154.3.8810624
Melatonin clearly has studies that show it benefits COPD as does NAC, which is purported to significantly reduce exacerbations at two 600 mg doses per day.
Generally elevated oxidative stress is considered to possibly be the single most important factor driving COPD disease progression, so these two seem quite useful and melatonin is the most potent antioxidant in the human body as I described in the original post. Maximum radical scavenging is desirable.HDM made it possible for me to get rid of a cough that I had had for months that was not getting better, only worse. With HDM it started to lessen in two days and was gone by the third day.Vitamin C is synergistic with melatonin and adds to both its antioxidant abilities as well as its antiinflammatory qualities.Quercetin is also useful for COPD and quercetin is also synergistic with melatonin increasing its antiinflammatory activity.
Vitamin D reduces the number of acute exacerbations also and it is almost always good to be vitamin D replete for overall health, especially with so many people being insufficient or deficient. Getting into the upper half of the reference range for 25 OH d is worth looking into at whatever vitamin D dose is needed to get there. Simply put, some people require more vitamin D to achieve a specific 25 OH d level. The 25 OH d reference range is 30 ng/ml ~ 100 ng/ml
Some essential oils such as eucalyptus are thought to be helpful with COPD also. Not everyone can tolerate melatonin. Does your mother in law have Afib?
Art
Melatonin
Melatonin
★★★★★
Thank you very much for your kind and thoughtful words!
Art
Melatonin
If the reason you are taking melatonin is to fight Covid, it only need be taken while you have Covid and up to 2 months after as a long Covid preventative.
The topic of retinal damage and melatonin was based on an old study in animals, where they gave high dose melatonin and then exposed them to very bright light which caused damage. First the melatonin was taken during the day when melatonin levels are lower. Most studies I have seen recommend and use melatonin at night and this is what I do also. Melatonin levels are normally higher at night and lower during the daylight hours. What was done to the animals in that study I would consider a form of torture.
So this was an abnormal use of melatonin and very bright light which humans don't regularly do. I only mention daytime use of melatonin for severe diseases such as Covid or cancer. In any case I have not seen similar results in human studies, but I have seen newer studies that suggest that melatonin use has beneficial effects for the retinas as discussed in this newer (May 2023) review of studies :
https://www.sciencedirect.com/science/article/pii/S0753332223002640
Here are two relevant quotes :
' MT synthesis-related genes in retinal tissue may be affected by age. Our study shows that MT can effectively restore NaIO3-induced retinopathy and maintain retinal structural integrity. Importantly, MT may assist the conversion of M1 to M2 macrophages to promote tissue repair, which may be caused by the increased infiltration of Tregs. Moreover, MT treatment may upregulate TET2, and further NT5E demethylation is associated with Treg recruitment in the retinal microenvironment. '
' Our findings suggest that MT can effectively ameliorate retinal degeneration and regulate immune homeostasis via Tregs. Modulation of the immune response may provide a key therapeutic strategy. '
The science of melatonin is continually evolving as new studies discover more positive effects that melatonin has on human, animal and plant health.
I have taken higher dose melatonin for over a decade based on studies I have read. I currently take my 132 mg of melatonin in the evening.
Art
Melatonin
Melatonin
Are your nose bleeds anterior or posterior? I too had been having them (anteroir) since Nov. It was an enlarged blood vessel that had to be cauterized (tried everything under the sun from a natural perspective) twice. The second doc explained in my case it probably was from dryness. He recommended a humidifier and ayr moistening gel. I notice when applying it, the tissue is dry on that one side. I also use a saltwater nasal spray. Hope your condition has improved.
Melatonin
We also used 50 mg of zinc not mcg. 🤦♀️
Melatonin
That was in awesome family venture. I am so happy for you and your family.
To me one the biggest battles I see families facing since 2020 is a purposeful effect to help one another stay well.
I came to NC to help an elderly Aunt. It has been trying venture to me to get me well and keep her well. I know the Lord has help us.
I happy to say she got the first part of her COVID Vaccine shot. She wanted it so bad, she has Faith in it. So I am happy for her. She's a tuff cookie and still fussing.
Thank God for family and Caring neighbors, and for our EC family.
HisJewel
Melatonin
Blessings, Charity
Melatonin
https://pubmed.ncbi.nlm.nih.gov/32217117/
China has also donated and shipped large amounts of drugs/herbs to the Philippines (where I live). They shipped Lianhua Qingwen (a COVID-19 anti-viral) and Melatonin as well as other drug/herbal combinations to be used in Filipino hospitals. The Philippine researchers have also wasted no time confirming the efficacy and safety of Melatonin which can easily be purchased from any Asian retailer website like Alibaba and Lazada.
Unfortunately, as Art and I have discovered, Chinese anti-viral herbs like Lianhua Qingwen capsules are not being sold on Amazon (banned by Jeff Bezos?) but they are sold on eBay. So now Amazon has been politicized in support of all that China-hate from all western govts, which is a great shame.
It also appears to me that the perpetration of all that China-hate propaganda in the western media seems to be way more important (sic) than western researchers actually knuckling down and making the effort to find a successful and consistent therapeutic anti-viral cure (with a 95% cure rate) for COVID-19 in order to save lives in the West. That's the way to go, not vaccines. And China is already there with her integrated medicine approach (but this has not being accurately reported or recognized in the West because of all the continual China-hate propaganda emanating from western, govt-led media who are so successfully blurring, distorting or just not reporting all the facts).
Melatonin
Thank you for coming back to update on your progress!
Yes, melatonin can cause diarrhea and while it is not a common side effect, it can happen. Here is a quote from my very last reply to you :
>>>I suggest you stop taking vitamin c, magnesium and melatonin as each one of these can cause diarrhea.<<<
..............................
In your case, the diarrhea did not come on for well over a week, which generally would suggest that you tolerate melatonin as in cases of diarrhea related to melatonin use are usually seen right away, at or near the first dose. This may be a good thing for you in case you get Covid-19 again. The antibodies appear to last for months, but apparently it varies with each patient. If you were, to get Covid-19 again, you could still try melatonin at the very beginning and stick with the melatonin until you develop diarrhea again and then stop taking melatonin. Your previous experience will be a very good guide for you!
You may have missed a post I wrote about a specific nasal spray called Xlear, but if you contract Covid-19 again somewhere down the road, I think the combination of melatonin and Xlear, may get you over it quickly and before diarrhea becomes an issue. Here is a link to that post about Xlear :
https://www.earthclinic.com/xlear-for-covid-recovery.html
Now regarding your question about a possible alternative sleep aid to melatonin, I have used Valerian Root Extract (VRE) and it is helpful for sleep. The zinc and magnesium should work well with it. A word of caution regarding VRE, It smells bad, and may be off putting for some people, so again it comes down to trial and error.
Your second question is more involved and would require much more information about what issues you are having that require supplementing.
Thank you again for the update, Mary Lou!
Art
Melatonin
Fauci: Masks don't work
Melatonin
Glad to hear your sleep has improved and even gladder to hear you have fared very well with your bout of Covid!
I think what Dr. Neel is doing is waiting until you test negative and then slowly reduce your melatonin dose until you get down to around 5 mg/night.
I believe the reason he is in no rush to take his patients off of melatonin too quickly is because Covid-19 has shown damage to almost all major organs in autopsies and studies suggest that melatonin can repair much of the damage that you can't see and is not readily apparent to the patient or doctor. This damage if left unchecked may cause health issues years down the road. I think the damage has the best chance of being repaired while it is relatively fresh.
Art
Melatonin
Melatonin
This recent study (June/2020) is in agreement with the idea of using melatonin against Covid-19, but their hypothesized dose rate is approximately 8 times greater than what Dr. Neel is using on average (1mg per kilogram/day) at 8 mg/kg/day and higher for severe cases! To put that in perspective, if you weigh about 175 lbs or 80 kilos, you would have to take about 640 mg of melatonin per day for severe Covid-19 infection!!!
https://www.melatonin-research.net/index.php/MR/article/view/83/562
I'm a fan of melatonin, but that is the highest dosing I have ever heard of in humans and even greater than what Dr. Shallenberger is using in his stage 4 cancer patients!!
Art
Melatonin
Thank you for the information!
Yes, as a matter of fact, my mother in law does have A-fib!
She is actually taking a small amount of melatonin right now. She has been in a nursing home for 9 months and when her sleeping pill prescription ended, they asked if they could give her melatonin instead. Well, I was sure happy about that! I don't know how much yet.
I actually didn't realize that COPD is what they used to call emphysema. But it makes sense.
Thank you again!
~Mama to Many~
Melatonin
★★★★★
This is an update from one of Dr. Neel's patients describing her experience using high dose melatonin (HDM) to treat her Covid-19 case. She adds confirmation to what Dr. Neel has been saying about the rapid onset of action by HDM (High Dose Melatonin).
Also of interest in this update is the fact that Dr. Neel appears willing to go slightly above his proposed dosing schedule of 1 mg of melatonin per kilogram if he deems it necessary.
This is essentially one patient's play by play of her experience with Covid-19 and HDM:
https://devinenews.com/ms-ovalle-shares-battle-with-covid-and-what-got-her-through-it/
Art
Melatonin
★★★★★
To me that is awesome news compared to all other major drugs being trialed and tested, as even the best of these are showing patients still dying, but at a lesser rate. Importantly, he once again reiterates the importance of vitamin D based on the Italian vitamin D statistical analysis as it relates to Covid-19 patients. In this latest update you can see that Dr. Neel is becoming even more focused in treating his covid-19 patients quickly and has had no major complications or deaths!
Dr. Neel also mentions the study trial in Manila that will treat 350 Covid-19 patients who also have pneumonia. It seems pretty bold to focus on Covid-19 patients with pneumonia, as this group has a significantly higher death rate!
Here is a link to his latest update:
Art
To date, studies still do not show a high efficacy rate for Ivermectin in use against SarsCoV-2 virus in humans. Dosing as high as 1200 mcg/day per kilogram have been used in a human study and while it did have an effect on modestly lowering viral load, that dose showed no benefit in terms of symptom reduction. Here is one RCT that shows viral load lowering effects, but minimal to no symptom improvement :
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8734085/
Here is a relevant quote from the RCT :
' This was the study with the highest dose of ivermectin ever used in a clinical trial for the treatment of COVID-19 or, indeed, for any other condition. The higher dosage (1200 μg/kg for 5 days) showed no safety concerns as no SADRs were observed. The co-primary efficacy outcome was the reduction in viral load on Day 7. The reduction (expressed in log10) was 2.9 for the higher dose (arm C), 2.5 for the lower dose (arm B) and 2.0 for placebo, but the differences were not statistically significant. No significant differences were observed in the clinical outcome either, although the study was not powered sufficiently to detect differences in the secondary outcomes. Concerning AEs, three of the four SAEs (hospitalisation for worsening of the disease) reported were in arm C and 1 in arm B. '
That dose for me would be almost 100 mg/day. In the study above they also tested a lower dose closer to the FLCCC protocol dose and it performed even poorer in terms of viral load reduction. I realize this goes against some anecdotal reports, but while I do consider anecdotal evidence to have value, I lean toward the scientific evidence that can be reproduced in subsequent studies and so far I have only seen modest benefit with Ivermectin alone at various doses in terms of significant efficacy.
For a more recent perspective, this is a July, 2024 study that used a dose similar to the lower dose of the FLCCC protocol at .4 mg per kg/day :
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11264372/
Here is a relevant study quote :
'Although viral load showed a significant reduction, there was no significant difference in the clinical progression of the disease according to the WHO clinical progression scale during the 28-day follow-up in the two arms (Table (Table3).3). Similarly, no difference was observed in the progression of clinical symptoms experienced by the patients during the follow-up period in the two groups (Fig. (Fig.2).2). These included specific symptoms such as loss of smell and taste as well as constitutional and respiratory symptoms, most of which were resolved by day 28. Nausea and vomiting were observed more in the ivermectin arm (Fig. (Fig.2)2) any serious adverse events were not noted with ivermectin. One patient died due to the development of severe Covid-19 pneumonia who was in the ivermectin arm, but it was not considered related to ivermectin. '
IMO, all of the above results suggest to me that Ivermectin, like many of the treatments for Covid-19 are better suited for use alongside other drugs or supplements than as a stand alone treatment.
Regarding melatonin, very early on in the pandemic (April 18, 2020), I wrote a significant amount about its potential use for Covid-19 here :
https://www.earthclinic.com/melatonin-protocol-for-coronavirus.html
Studies since then have consistently shown that melatonin has multiple benefits in the treatment of SARS Cov-2 / Covid-19 and because of its multiple methods of action is likely to be beneficial for long covid also which I have written about here:
https://www.earthclinic.com/cures/supplements-for-long-covid.html
There are numerous studies showing the effectiveness of melatonin to reduce or prevent the use of a ventilator, to prevent covid pneumonia, to reduce hospital days required, significantly reduce symptoms and significantly reduce death from Covid-19 as well other health benefits.
Here is a more recent study (June 19, 2023) discussing melatonin and Covid-19 :
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10614475/
Here is a relevant quote from the link :
' The hormone melatonin works as an anti-inflammatory, antioxidant, immunomodulator, and strategically slows down the cytokine release which is observed in the COVID-19 disease, thereby improving the overall health of afflicted patients. The medical community is expected shortly to use remedial attributes like anti-inflammatory, antioxidant, antivirals, etc., of melatonin in the successful prevention and cure of COVID-19 morbidity. Thus, the administration of melatonin seems auspicious in the cure and prevention of this COVID-19 fatality. Moreover, melatonin does not seem to reduce the efficiency of approved vaccines against the SARS-CoV-2 virus. Melatonin increases the production of inflammatory cytokines and Th1 and enhances both humoral and cell-mediated responses. Through the enhanced humoral immunity, melatonin exhibits antiviral activities by suppressing multiple inflammatory products such as IL-6, IL1β, and tumor necrosis factor α, which are immediately released during lung injury of severe COVID-19. Hence, the novel use of melatonin along with other antivirals as an early treatment option against COVID-19 infection is suggested. Here, we have chalked out the invasion mechanisms and appropriate implications of the latest findings concerned with melatonin against the virus SARS-CoV-2. '
Imo, melatonin has the anecdotal reports and the backing science to establish itself as an important supplement for the treatment of Covid-19 as well as long covid. In my limited experience I have seen melatonin reverse mild to moderate Covid-19 in 3 days, similarly to what you reported.
Regarding avian bird flu (H5N1) Ivermectin may be worth considering, but data is scarce. Same with melatonin. Melatonin is thought to be beneficial via its known methods of action and has proven itself to prevent a cytokine storm which can be deadly.
Art
Melatonin
In my opinion, silver nanoparticles (AgNPs) are likely going to be helpful for both H5N1 and monkeypox, but I would not use it as an oral preventative because I don't think it is good to take it everyday in the long run, due to the potential for bacterial resistance. Oral AgNPs are likely best used during active infection and the earlier it is started the better. I can also inhale the AgNPs using a nebulizer or cold process vaporizer for specifically targeting the lungs. Obviously I would use melatonin simultaneously for its multiple methods of protective action to try and offset the negative health effects of viral diseases.
If I want to use AgNPs as a preventative for monkeypox virus or H5N1, I use it as a spray that you carry with you and use as I mentioned that I do for Covid-19, by spraying it up my nose, in my mouth and on my skin, if needed, whenever I am in crowded places where monkeypox or H5N1 can transfer from person to person. I carry a two ounce spray bottle in my pocket and it works well for me for these purposes.
The following article discusses the antiviral activity of AgNPs against various viruses :
https://www.sciencedirect.com/science/article/pii/S205566402300016X
Here is a relevant quote from the article :
' Recently, the antiviral activity of AgNPs against viruses such as HIV-1, 11, 12 hepatitis B, 13 herpes simplex, 14 respiratory syncytial, 15 and monkeypox16 has also been studied. Their primary antiviral mechanism is the physical inhibition of binding between the virus and the host cell. The dependence of antiviral activity on the size of AgNPs was observed for all the above viruses. For example, AgNPs less than 10 nm specifically inhibit HIV-1 infection.11 They exhibit anti-inflammatory, antiplatelet, and antiangiogenic activity17, 18, 19 and generally have a broad biological activity spectrum. Thus, AgNPs could potentially be used as antiviral drug with a wide range of action, minimum toxicity, and be capable of altering their mode of action during their interaction with various viruses. '
Note in the article above, they discuss a little bit about the particle size of AgNPs influencing their activity against specific viruses such as HIV. From everything I have read, particle size in the the 10 to 20 nm size is the range that will have the higher effectiveness against pathogens while being less toxic to normal cells. Particles smaller than 10 nm can be more effective against pathogens, but that size range is also more toxic toward normal cells. When the particle size goes above 25 nm, the toxicity of the AgNPs to pathogens decline the larger the particle size gets. So the particle size range in the 10 to 20 nm range is a more optimal size range for toxicity to pathogens and less toxicity to normal cells.
AgNPs have also shown significant activity against various influenza viruses.
I don't know if EC still sells AgNPs or not, but based on the color of their product in the yellow range as well as it being 20 PPM, it is likely to mainly be in the 10 to 20 nm particle size range.
Art
Melatonin
arrivederci!!!
EC: We put Art's post in the Monkeypox page article yesterday. Thank you, Art!
Melatonin
Another helpful supplement would be berberine as discussed here regarding the influenza A virus of which avian bird flu is a subtype :
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150991/
Another supplement I would consider is a homeopathic remedy that I have had very good experience with for flu in general :
Art
Melatonin
Nosebleeds are not a listed side effect of melatonin, however it does have anticlotting effects and this could cause nosebleeds in sensitive people, especially if you are taking a blood thinner of any type such as Warfarin, Ivermectin or even supplements with blood thinning qualities like vitamin E, Nattokinase, Curcumin, garlic, Bromelain, grape seed extract and fish oil to name only a few. This is part of what makes melatonin and these other supplements useful for heart and vascular issues, but in your case it may be the cause or part of the cause of your nosebleeds.
It sounds like you are not going to be able to use melatonin and now that you are aware of the problem, it will be a good idea to check on the anticlotting and or blood thinning effects of other supplements you may be considering including Ivermectin.
One of the damages caused by Covid-19 is blood clots for which melatonin is quite useful for preventing, but in your case, the nosebleeds would be a problem. This is why I often remind that not everyone can tolerate melatonin.
Art
Melatonin
This could be a vitamin B deficiency. I would either start taking a b complex 50 or 100 daily, or start taking a teaspoon of Molasses a day.
I sometimes I put a teaspoon of unsulfured blackstrap molasses, and up to a half teaspoon of baking soda in a glass of water and drink it down if I get a nose bleed. I would do this a few days or so to make sure the situation is addressed. Research vitamin B for nosebleed.
HisJewel
Melatonin
Thank you regarding my recovery from those symptoms!
If your reason for taking melatonin is to treat Covid-19, you don't need to take it unless you get covid. There was one study where they determined that melatonin may have a preventative effect. Dr. Neel mentioned that there is one anecdotal report where 20 mg may have a preventative effect, but this has not yet been scientifically proven.
If you had the melatonin hangover a couple of years ago at a low dose, you are still likely to have that issue at 10 or 20 mg.
If you do get Covid-19, the daytime sleepiness is likely to be a benefit as many report disrupted sleep with Covid-19. Good luck and keep us posted on your testing!
Art
Melatonin
Sincerely,
J.
Melatonin
When melatonin is used as a treatment for Covid-19, daytime drowsiness is probably a good thing, because it allows you to sleep and during REM sleep the body can heal well. The other thing is that you really can't go anywhere if you are infected because your doctor will want you to self quarantine for so many days from the day you first notice symptoms.
When using melatonin for other health issues, two ways that have shown in studies not to cause daytime drowsiness is taking melatonin intravenously or as a suppository. For me, I found that regular use of oral melatonin helped to eventually get rid of the melatonin hangover over a period of about 2 to 3 weeks as the body self adjusts to increased melatonin levels. Staying very active during the day was most useful to minimize the daytime sleepiness.
As I've mentioned many times on EC, not everyone can tolerate melatonin, so if side effects are too much from melatonin, then melatonin is not an option for that individual. The majority of people tolerate melatonin fine, but for those who do not tolerate it, melatonin use is precluded.
Art
Melatonin
I've enjoyed your articles on melatonin. I have a question with regards to the last discussion you posted and the dosage. You were at quite a high dose compared to what is usually recommended.
Did you titrate up to that amount, and if so, how slowly or quickly did you do that, and does it leave you groggy at all? Thank you for the wonderful service you provide in sharing your information!
Melatonin
Liposomal melatonin is fairly expensive and Dr. Neel has not used it in his patients, so he has no data to show if it is more effective than regular melatonin for Covid-19. More importantly, he has no data on how to dose the liposomal form of melatonin.
On Amazon, many of these liposomal melatonin products are $40 for one ounce.
Melatonin
Tramadol is used for pain, but melatonin can increase the known side effects of Tramadol.
One of the common side effects of Tramadol is a lightheaded feeling like you might pass out! Sound familiar?
https://www.drugs.com/tramadol.html#side-effects
I would advise against that combination to be sure!
There are other drugs that should not be taken with Tramadol and alcohol is a definite NO! Your pharmacist can advise you everything to be careful of with Tramadol.
Art
Melatonin
Thank you very much for your feedback on melatonin for Covid-19.
Your results seem to mirror what Dr. Neel has seen in his over 1,000 C-19 patients that he has treated with HDM. He reports rapid turnaround in symptoms very shortly after initiating HDM.
Regarding your husband taking 10 mg and still getting Covid-19, in the symposium that Dr. Neel recently attended, the general consensus among the doctors, researchers and scientists at the symposium, 20 mg was the suggested preventative dose.
Regarding the headache from taking melatonin, this is a known side effect, but in the people who I have talked to with this issue, like the "melatonin hangover", it tends to reduce as the body adjust to more melatonin in the system.
The question I have is, since you started the other supplements prior to HDM, did your husband notice any improvement from them or did he just see improvement once he brought his HDM dose up to par?
Thank you again, Annette for the feedback as it adds further confirmation to the effectiveness of HDM.
Art
Melatonin
If you mean 5HTP, it is not the same as melatonin and it does different things than melatonin. If you are in England, I believe that melatonin is by prescription only and it may be a problem trying to get a doctor to prescribe the high dose you would need? Perhaps an EC member from your side of the pond can suggest a source???
Art
Melatonin
For people in Europe order at iherb.com. I am from Switzerland and here Melatonin is absolutely forbidden. You get a prescription only after 65 for only 0,5mg. I have ordered the Melatonin, in case somebody near me gets Covid. Fortunately we have not yet have to use it. Good luck M-L
Melatonin
Thank you for the great feedback on your Covid-19 / melatonin experience!
Based on what you wrote, it appears that your Covid-19 "preventative protocol" was insufficient to actually stop or reverse the virus progression in your system as suggested by your steady system increase during those first 7 days.
My opinion of your preventative protocol is that most of those components are synergistic with melatonin and can improve the outcome of the melatonin treatment, but without melatonin they are insufficient and I feel that your experience adds confirmation to this theory.
From what I have seen so far with most things being tested for Covid-19, the sooner they are initiated, the better the outcome. Unfortunately you weren't able to actually take melatonin until a week had passed and this allowed the virus to multiply unabated that first week and the increased viral load seems to be confirmed by that continuing increase and worsening of your symptoms in that first week.
Studies of Covid-19 show that increased viral load equates to worsened symptoms and sometimes death, while lower viral loads equate to moderate to being asymptomatic and living.
On the 7th day, your first day of taking melatonin, you already had very significant symptoms and you only took a 40 mg dose of melatonin and that allowed you to get good sleep which is actually very good! Some people say that melatonin can make them feel tired the day after they take it, but it is a good thing to sleep and reach REM sleep where your body is able to do a lot of needed repair work.
Consequently, even though you only took 40 mg of melatonin the night before, you already felt a smidgen better the next morning which was a first! This is exactly what Dr. Neel has been reporting in his patients with noticeable improvement the day after the first dose. Dr. Neel recommends to other doctors to give their patients 1 mg of melatonin for every kilogram of body weight.
I don't know what you weigh, but 80 mg is probably close enough to that dosing schedule to work as Dr. Neel has been reporting in over 400 Covid-19 patients treated successfully so far.
On the 8th day, you actually took your first full 80 mg dose of melatonin that you planned to take. You noticed increased coughing and again, this can be a good indication because one of the first things that melatonin does is reduce inflammation in the lungs and with reduced inflammation and consequently reduced swelling in the lungs, the body will attempt to start clearing fluid and mucus buildup which would represent as increased coughing that should be more productive than previous coughing.
The symptoms on day 8 are to be expected.
Day 9, your second day at the full 80 mg dose again showed symptom improvement and that was to be expected.
You stated, >>> ' I felt fairly good, but shaky, a little dizzy, weak, tired, and coughing a little less. I reduced Vitamin C to every 2 hours.' <<<
Again, you are showing improvement at just your second day of full dosing!
One thing that has been shown by Dr. Neel and studies is that vitamin C has synergy with melatonin, so it may have been a bit premature to reduce the vitamin C dose, but that is unknown for certain in your case. Remember that your original preventative formula mostly has synergy with melatonin.
Day 10 you reported reducing your vitamin C dose even further after getting a little diarrhea. This is where the way the post I wrote on this subject gets a little harder to follow.
You see, whenever I got new information regarding using melatonin for Covid-19, I can not add that information to the original post, so I have to add it as a "reply" to the original post so if you don't read the whole original post "and" all of the replies to that post, you will not get all of the information needed.
In one of my replies I said that in later cases of Covid-19, Dr. Neel is seeing gastrointestinal issues that he did not see in his first 200 patients or so and he surmised that these gastro issues were likely related to a mutation of the viral strain. His solution to the problem was to add an antibiotic to try and kill whatever bacteria was causing the gastro issues, but you were probably not even aware of that update. Now if you were going to try to use some type of natural antibiotic to treat the diarrhea, it would probably be things along the line of garlic, Olive Leaf Extract, Grapefruit Seed Extract, Colloidal Silver etc.
Really just a personal choice based on what you prefer.Day 11 went fairly well with tiredness, a light cough to clear the lungs and more sleepiness which would all be expected on your third day at full dose melatonin. No mention of diarrhea.Day 12 sounds really good and again no mention of diarrhea.Day 13 sounds similar to day 12 and no mention of diarrhea.
Day 14 you said, >>> ' I considered myself healed at this point. ' <<<
On this point I would completely disagree. Your symptoms may have abated, but this in no way means that you are no longer sick! I think that many people think that if they have no symptoms, then they are no longer sick.
You are only on your 7th day of melatonin at full dose and you started a week later than you should have which essentially gave the virus a head start. Chances are you would have still tested positive at that point and to let up at that critical point is a mistake imo.
For myself in a similar situation, I would have continued with everything for at least a week more and I would probably gone even longer than that with the melatonin. Here is why. In the beginning of the original post I am talking about all of the damage that Covid-19 has shown in autopsies to many of the major organs and melatonin has shown the potential in other studies to help prevent or lessen this damage which can in time become long term or possibly life long damage.
It is my opinion, based on melatonin studies, that much of this damage can be prevented or reduced with longer use of melatonin after all symptoms have cleared. No mention of diarrhea.
From day 14, you skip to day 25 and I assume that you are relatively okay during these 11 days.By day 25 you have cut back on everything and are now trying different things to control the diarrhea.
I believe that the ACV with baking soda is a bad idea as you do not want to raise stomach pH as one of the purposes of stomach acid is to kill bacteria that enters the stomach with your food and imo can possibly be a reason for the diarrhea.
Eleven days with no symptoms suggests that you had the virus under control, but reducing stomach acid via your alkalizing method does not seem like a good idea imo.Unless I missed something, none of the things you have been taking seem to have strong antibacterial effects, except curcumin, but it is not well absorbed and would likely require a high dose, but I have no knowledge of using curcumin in this way.
The supplements I mentioned above, do have antibiotic effects as do others. Generally, but not always, diarrhea is caused by a bacteria and in your case you do not know the exact cause at this point, but if you went to a doctor, he might put you on an antibacterial regimen to try and kill any bacteria that might be causing the diarrhea.
ACV by itself might be helpful because of its low pH, but likely insufficient for full blown diarrhea and by adding baking soda to the ACV, you are significantly raising the pH of the ACV and possibly your stomach acid depending on what dose you have been using thus nullifying the possible benefit of the ACV.
Ideally, a visit to the doctor to take and test a stool sample to find out if it is a bacteria and which bacteria and knowing which bacteria would be very useful. With that knowledge he would know the best antibiotic to use. Failing that, you have a decision to make to either go to the doctor or decide if you are going to try and use naturals supplements with antibiotic effects on the diarrhea.
I am not a doctor and can not tell you what to do regarding the diarrhea.This diarrhea situation is questionable at this point whether it is related to Covid-19 or not because you went well over a week with no symptoms or diarrhea and Dr. Neel's reports only discussed earlier onset diarrhea which you did recover from, but those reports are not overwhelming with information.
It is entirely possible that this current diarrhea is unrelated to Covid-19 as even you thought that it might be food poisoning.
Art
Melatonin
I found that NAC 600 mg twice a day has really helped.
Then I do a steam as I do not own a nebulizer with Theranaturals glutathione, one capsule and one drop of eucalyptus essential oil. This glutathione is made for nebulizers. Eucalyptus is beneficial for lungs.
I do not do HP.
You could try above.
Covid takes a long time to recover.
Melatonin
https://pubmed.ncbi.nlm.nih.gov/32597503/
Art
Melatonin
Q90FM may be able to help, too:
https://www.q90fm.com/prayer.php
🌞
Melatonin
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Regarding your first question, that is not an issue I have seen reported in the literature, but melatonin does have blood thinning and anticlotting properties, so in order to find out if it is the cause for the hematoma, try stopping it for a month and see if that resolves the issue. If it does help, and since you are in good health, perhaps you can use a lower dose. Melatonin at 50 mg/day has shown the ability to return elevated oxidative stress levels, in people with disease, back to healthy control levels and this would be very useful for maintaining health long term. Lastly, you can get melatonin naturally by exposing yourself to earlier morning and later afternoon sunlight and get a little vitamin d at the same time. I always recommend this to people who do not tolerate oral melatonin because naturally derived melatonin seems to come with no side effects. I wrote a little about that here :
https://www.earthclinic.com/supplements/how-to-increase-melatonin-naturally.html
Regarding blue light glasses and whether they are useful for preventing eye fatigue and blue light exposure, so far they have not shown a good ability to do that and the following article discusses that topic :
https://www.publish.csiro.au/hc/Fulltext/HC23101
Continued good health to both you and your husband!
Art
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One concerning thing is the past two months I have had nosebleeds every morning. I was reading this thread and was surprised to learn that Melatonin can cause this. Is this true? I've been wondering why I suddenly have chronic nosebleed having rarely suffered in my whole life up to now. I think I will continue with the Melatonin especially if it will help with my gut inflammation (although it has not done so yet but I am hopeful).
Any suggestions, Art?
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I have 5mg tabs and they do not put me to sleep and I feel a little hungover the next day. Do I need a higher dose?
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Anyway, I think you got a false negative. If you can get the antibody test that would be interesting to see what it says.
Thanks for your post,
KK
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I forgot one other in the melatonin series, COPD and the next one is a very common one also.
Art
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Thank you for this information! It is important because melatonin has shown itself to have fairly poor availability estimated to be in the 3% to 15% range, so ways of improving that bioavailability would be useful.
Art
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Greetings from HisJewel,
My performance is Regular "Nature Made" Melatonin.
However if you need to stay away from sodium these may not be right for you.
I did not want extra sleep agents, sugar, nor fast dissolve tablets. So ended up with these and I was able to stay active with them all day until I went to bed.
The sleep was only 2 hours then on and off until morning.
However, remember they have sodium.
HisJewel
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My 88 year old mother has covid. No respiratory issues but overwhelming fatigue, extreme muscle soreness especially in the legs and hips and generally feels absolutely awful. I have 10 mg store brand melatonin on hand but am about to head out to purchase some more. Do you take the different forms of melatonin together or separately throughout the day. I'm nervous about the high dose but will take a leap of faith on this with few other options . She's about 130 lbs and will give her 80 mgs per day. Can you confirm that that seems appropriate just for my peace of mind. Don't expect my doctor would know the first thing about this. Thank you!
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Dr. Neel is using a minimum of 1 mg per kilogram of body weight in most of his patients. They are using significantly more in Manila. Given your mom's weight, if she is going to follow Dr. Neel's protocol, 134 lbs. = 60.7814 kilograms as shown here :
Based on Dr. Neel's regimen, your mom should be taking 60 mg of melatonin in divided doses throughout the day.
Melatonin can interact with other medications so you should either ask her doctor if melatonin is compatible with all medications your mom is taking. If her doctor doesn't know the answer, your mom's pharmacist should. As a last resort, you can call Dr. Neel at (830) 538 - 3550
Here is a link to a video that discusses Dr. Neel's protocol as well as dosing used by doctors in Manila and includes a discussion by Dr. Reiter, a world renowned researcher in melatonin. Very good information for anyone considering the use of melatonin for Covid-19 and other health issues :
Melatonin, like all other treatments for Covid-19, works best if initiated at the very first symptoms of infection.
Art
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Here are a couple of links to information on the use of high dose melatonin (HDM) for Covid-19 which you may find helpful.
https://www.earthclinic.com/melatonin-protocol-for-coronavirus.html
https://www.earthclinic.com/supplements/melatonin-research-for-covid-19.html
Art
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https://medicalxpress.com/news/2020-11-melatonin-covid-treatment.html
Art
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I'm not surprised at him using melatonin. Like many things about this administration, it's one rule for them and another for the hoi polloi. Maybe now some people will realize that masks work.
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I did test melatonin in the sublingual form, but did not notice any difference and the report you are referring to occured around the same time that Dr. Neel reported a more difficult strain of Covid-19 in his patients that was requiring more time to see improvement and in some cases he was using even higher dosing. I suspect that report was reflecting the tougher strain that Dr. Neel had mentioned that also came with digestive issues that he previously had not seen in his covid patients. I believe this may have been the reason for the report of a delayed response in that family.
As far as dosing of zinc, vitamin D and vitamin C, unfortunately they did not state the dosing used, in the article.
One of Dr. Neel's patients in an earlier report mentioned 2,000 mg of vitamin C total per day.
The Italian study suggested a serum level of 40 to 60 ng/ml for a good response to vitamin D, but again vitamin D serum level has to be tested regularly in order to reach a specific level such as 40~60 ng/ml and the dose will vary from person to person as some people simply require higher dosing than others to reach a specific serum level. The reference range for vitamin D / 25 (OH) d serum level is 30 ng/ml ~ 100 ng/ml and would need to be tested by your doctor to get there.
Art
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I had similar symptoms after what could have been COVID, but didn't get tested. I read on Curezone that we need 150 mcg of iodine a day, some for digestion. The recommendation was to take 100mcg of 5% Lugol's solution a day (16 drops) if you have problems with gut or thyroid AND for COVID. I did and my loose stool was instantly stopped and so was whatever I had (upper and lower respiratory symptoms). It wasn't even minutes. I will continue to take that amount until I get myself iodine saturated.
I also take co factors: Vit c, Selenium 55-400mcg, zinc 25 mg-higher and copper. (I haven't taken the copper yet). I also take a good probiotic.
Melatonin
Last time we spoke, I mentioned that you had a decision to make regarding the diarrhea, either go to the doctor or continue trying to fight it with natural substances. You have now tried the latter and the effort has not been successful. You can not continue with the diarrhea as this is preventing your body from absorbing nutrients from food you are eating, so this now leaves the doctor option so that he/she can determine the cause of the diarrhea.
In case the doctor is not able to see you immediately, you can try Pepto Bismol tablets, not the liquid, to help you last until your doctor appointment. Take as directed on the box. The doctor can take a stool sample and also test you to see if you now test negative for Covid-19. From what you have written, it sounds as though the diarrhea is your only symptom, but this is serious and needs to be stopped as soon as possible. A word of warning, the bismuth in Pepto Bismol tablets will turn your stool a blackish green color, so do not be alarmed about that.
I suggest you stop taking vitamin c, magnesium and melatonin as each one of these can cause diarrhea.
Please come back and update us on how it is going for you.
Art
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1- The only side effect I've noticed till now is that whenever I bump into something I get a big hematoma afterwards. Have you noticed this on yourself too?
2- So I assume blue light glasses are not necessary while we use our laptops in the evening?
thank you again for your very informative reasearch, God bless you!
Paola
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Do you think one could do the melatonin along with perhaps ivermectin?
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Soft gel capsules improve melatonin's bioavailability in humans Sara Proietti, Gianfranco Carlomagno†, Simona Dinicola & Mariano Bizzarri † Lo.Li Pharma s.r.l, R&D Department, Rome, Italy
Objective: Oral bioavailability is one of the most important properties in drug design and development. A poor oral bioavailability can result in low efficacy and unpredictable response to a drug. Several dosages of melatonin have been used for various investigations to clarify its bioavailability in humans. Aiming to search for a pharmaceutical form, which is better absorbed, the pharmacokinetic (PK) profile of the new manufactured melatonin soft gelatin (soft gel) capsule form has been evaluated and compared with the commercially available melatonin powder. Research design and methods: A total of 60 healthy volunteers received 1,3 mg of melatonin powder and 1 mg of melatonin in soft gel capsules. PK profiles were obtained by analysis of melatonin plasma concentration, and the respective melatonin bioavailability was compared. Results: Melatonin soft gel capsule form showed similar PK parameters compared with the highest doses of melatonin in powder form, but its bioavailability was improved. Conclusions: Soft gel capsules improved the bioavailability of melatonin in humans even when administered dose was reduced. Considering the number of conditions in which melatonin supplementation is recommended, this evidence could support a broader use of melatonin in clinical practice
Hope you read this, greetings from south texas
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Some people simply can not tolerate melatonin and that may be the case with you based on how sensitive you say you are to it.
What you can consider and ask your doctor about is Xlear nasal spray which may be helpful. Here is a link to a post I wrote about it :
https://www.earthclinic.com/xlear-for-covid-recovery.html
This is a fairly non invasive approach that showed benefit in a few Covid-19 patients. There are currently 95 other Covid-19 remedies listed on EC. It may be worth looking at some of those here:
https://www.earthclinic.com/cures/coronavirus.html
Art
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I'd hoped to circle back with a nice concise report. I am doing well but it has been a bit of a roller coaster.
I'd been experiencing symptoms for a few weeks, but didn't suspect Covid as they didn't fall into what I was hearing. They continued worsening up to diagnosis.
Early symptoms included migraine-type head pain.
Diarrhea, but not as early as headache. Itching-I haven't seen much about this but it was intense. It started on my scalp and then to feet, hands and trunk. Insomnia.
I began HDM the day after my diagnosis. Within 24 hours, ALL SYMPTOMS had significantly improved! The continuous head pain had lessened. Gastric issues cleared up. I did continue to get what I called 'floater' headaches. The pain wasn't continuous throughout the day but came and went.
Do not ask me why but at some point, I thought I was good and cut way back. Symptoms returned with a vengeance.
I went back to recommended dosage of 1mg/kg of body weight. Things got better again right away. Headaches tended to stick around and seemed to be getting worse. I read that melatonin can sometimes cause headaches so again, I cut myself off. Once again, they got worse. I decided to increase dosage. I did this 25% at a time. 25% of my initial dose. It seemed to help until it didn't.
After catching up here, I am going to continue to increase more. I've had issues in the past with headaches but had gotten to a place where I was not having so many. That's about the only symptom that seems to be lingering.
I am over 2 months out, so I suppose I have crossed over to the residual symptom category? I don't know, but I am going to continue to try to get back to pain free. I will not increase up to the 80mg dosage in the report but I will not be afraid to nudge it up some.
Again, thanks so much for your input here and sorry to be so long with update. Stay well!
Karen
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Thank you very much for the feedback and I am glad to hear that melatonin worked out well for you!
Yes, headache is a known side effect of melatonin and Covid-19. My experience is that the headache generally goes away with continued use, but it is difficult to determine which may be the cause of the headache. Headache is very common in Covid-19, but not much with melatonin. Since you already had the headache before you started melatonin, I would lean toward Covid-19 as the culprit.
The "few weeks" late start with melatonin makes it a tougher battle as Covid-19 has quite a head start to attack all that it is known to attack, but this clearly shows that even when used late, melatonin can still be quite effective against Covid-19, unlike Hydroxychloroquine, Remdesivir and Faviparivir.
Rash and itching have been seen in Covid-19, but itching without rash is less common. The skin is an organ and Covid-19 is showing that it can attack almost any organ in the body including the skin, based on autopsy results.
It seems like the earlier melatonin is started, the better the outcome, but melatonin has also shown benefit for patients who were already on a ventilator when the melatonin was started, improving the outcomes for ventilated patients who received melatonin.
Letting up early after starting late, is likely to be a more difficult recovery, but melatonin is showing that it is up for that challenge.
One person on EC reported that they started at even higher dosing than Dr. Neel's recommended 1 mg per kilogram of body weight at the first symptoms and their symptoms were almost completely gone the next day, so early timing definitely seems to matter!
On a related note, with the variant strains of Covid-19 that are being reported, even if you get a vaccination, it may be worth keeping melatonin on hand just in case the vaccine is not effective against the variant strain that you get. Having a fallback plan just in case seems like a good idea.
Lastly, I still feel that the inexpensive combination of Xlear Nasal Spray with melatonin maybe a good one two punch against Covid-19. Here is a link to a post I wrote about Xlear Nasal Spray and Covid 19.
https://www.earthclinic.com/xlear-for-covid-recovery.html
Thank you again for the feedback, Karen!
Art
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10/18/2020, Sunday.
As promised, I'm coming back to relay my experience with Covid and using Melatonin. However, I will make two separate posts. This one will be a continuation of the post for Covid related diarrhea.
This is the 3rd week of diarrhea. I implemented your suggestions of 50mg Zinc and ¼ cup blackberries a day. I restarted my COVID protocol which included 80mg of Melatonin. I also added Psyllium Husk (5 capsules, 3 times a day). I stopped the High Dose of Zinc and the Psyllium on Saturday. I felt I needed to give the Psyllium a rest and you'd suggested a short term of the High Dose of Zinc.
I did implement your suggestions with Magnesium, Zinc, and Melatonin from your Restful Sleep post.
I was seeing a slight improvement with stools being a little more formed and duration decreasing a little by Thursday/Friday.
Previous to this week there was no diarrhea during the day or evening. This week (depending on what I ate) I would have a very loose movement or two 30 minutes to an hour after eating.
Today the diarrhea is back to mostly liquid and the duration was about 3 hours. Then this afternoon, within a few minutes of drinking water or coffee, I'm back on the commode.
I'm testing Activated Charcoal today and moving to Turmeric. I may have started my doses too close together at the beginning and the Charcoal may have offset the Turmeric.
I work, so taking all these supplements at the right times is challenging. That's one reason I wanted to stop Psyllium.
I will continue to take my Covid Protocol.
Do you have any other suggestions?
Again, Jasmine and Art, thank you for inquiring about my status. Carol, thank you for your suggestion.
I found out that the diarrhea was indeed caused by Melatonin. As I posted in October 29th, I stopped all supplements except Melatonin. I was taking 80 mg, and then 40 mg of Melatonin daily from about 9/12/2020 to 10/29/2020.
In Art's post about Ulcerative Colitis and IBD he stated, "The 5 mg dose is a good place to start as some people cannot tolerate melatonin " When I read that In October, I stopped Melatonin too. Within 24 hours there was a dramatic change in my bowel habits – not back to normal but enough of a change to know I'd found the cause of the diarrhea.
However, due to nearly (5) weeks of diarrhea and stomach turmoil, it was nearly another (5) weeks before my bowel movements returned to normal.
I tested 5mg of Melatonin a couple of nights ago, because I had been sleeping so much better when I was taking it. I found out that I'm still Melatonin intolerant as diarrhea returned for a couple of days.
Several folks in my office tested positive for Covid in November so I re-tested even through I didn't have symptoms. I still tested positive. However, I didn't have to quarantine as our Kentucky Health Department told me there is a 90-day rule and I was about day 87. It basically states, that if there are no new symptoms, then the virus is “residual” in your system and not contagious. (I may have my terminology incorrect, but you get the gist of it.)
Bottom line, I've been feeling very good lately. I still have a little cough occasionally in the morning. I clear my throat/lungs and it's gone. I've always had a little sinus issue.
I'm back on most of my supplements and have added
Colloidal Silver, 30 Mg, ½ tsp 3x Day - I'm on my 2nd bottle and will stop after the 3rd
1 Tbsp Coconut Oil in coffee at least once a day;
Lysine, ¼ tsp, twice a day;
Black Seed Oil, 1 tsp/day
Hemp Seed Oil, 1 Tbsp/day
My questions now are:
1. Is there something else for sleep in place of Melatonin?
a. I'm still taking Magnesium, Zinc, and D at night and DHEA in the morning.
2. Is there a protocol/suggestion for what supplements are good to take on a daily basis for optimal health? And how much of each. (My pantry is full of supplements and I feel like I'm taking too many and maybe too much of some and not enough of others.)
Thank you for all you and Earth Clinic do to help us.
Melatonin
Regarding the blackberries, that seems like a reasonable dose to start with and see how you do with it. Regarding the zinc, I split my dose as the zinc is useful for sleep so I take half of the daily dose about an hour before bed with the other two supplements as I mentioned in my post about pursuit of restful sleep here:
https://www.earthclinic.com/art-solbrig-insomnia-protocol.html
Good luck and I look forward to your update!
Art
Melatonin
10/18/2020, Sunday.
As requested and promised, this is my post on my COVID experience and using Melatonin. I don't know that it will be sufficient evidence to support any one protocol, but maybe it will help someone.
I've tried to re-create the two weeks that I had COVID as best I can. I was not interested in documenting it at the time, but started after a few days.
My first symptoms were about 6 days after I believe I was infected. On Thursday, 9/3/2020, I had the worse sinus and head cold symptoms I'd had in my life. That was the day I was told I had been in contact with a person who tested positive.
I had been taking a COVID preventative protocol for about a week. These included Alkalizing, Vitamin C, D, Zinc, Querticin.
The next two days I felt better in the morning and worse in the evening.
By Day Four, I felt more flu like symptoms. Very severe head cold and sinus congestion, an occasional cough, and very tired. I went back to earthclinic.com for additional suggestions and the EC staff pointed me to your Melatonin posts. I ordered some.
Day 5 was very bad “flu” like symptoms. I started taking 1000mg of Vitamin C extra times during the day. The highest fever I had as 99.1.
Day 6 still the same. I started taking 1000mg Vitamin C every hour.
Day 7 I received my order of Melatonin and added 40mg that evening to my current protocol. After the first dose of 20mg at 4:00 p.m., I was so sleepy I took a 3 hour nap. After the 2nd dose at 9 p.m., I slept till about 10 a.m. the next day. I had already started to feel a little better today.
Day 8 I added the full 80mg Melatonin today. It didn't knock me out like the two yesterday. I coughed more today than I had since this started. The worse symptom was weakness, tiredness and being shaky on my feet.
Day 9 I felt fairly good, but shaky, a little dizzy, weak, tired, and coughing a little less. I reduced Vitamin C to every 2 hours.
Day 10 I didn't feel like getting up in the morning. I was more congested. I reduced Vitamin C to every 3 hours as I was having light diarrhea and thought I was saturated with Vitamin C.
Day 11 I felt fairly good except for a little cough in the morning to clear my lungs and still tired and sleeping a lot.
Day 12 I felt fairly good today. I still had a little cough in the morning to clear my lungs. I actually walked about 2 blocks before wearing out. I was still sleeping a lot.
Day 13 I felt fairly good today too. I still had a little cough, congestion, and weakness.
Day 14 I considered myself healed at this point.
Over the next couple of days, I cut back on the melatonin.
Day 25 This was about a week and a half later and later severe diarrhea started. At first I thought it was food poisoning. When that didn't clear, I started back on my COVID treatment protocol including 80 mg of Melatonin.
At first the diarrhea only happened first thing in the morning and lasted 1-3 hours. It started severe, explosive, and liquid. I stayed on the BRAT diet and/or ate light. After (2) weeks, I ate other things and sometimes had diarrhea after lunch or dinner, but only 1-3 movements, then I was usually good.
I started back to work on 10/05/2020 feeling good except for the diarrhea.
I tried most of the popular EC remedies for diarrhea. Charcoal, Turmeric, and ACV didn't help. I added Psyllium and it helped just a little. Last week I upped Zinc to 50mg and ate ¼ cup blackberries.
I felt I needed a break from all the supplements on Friday, 10/16/2020. So Friday night and Saturday I stopped the psyllium and a lot of the supplements. Today, Sunday, 10/18/2020, the diarrhea was back full blown and for about 3 hours.
I wrote a previous post on the diarrhea only and am hoping for more help with that.
Here is my COVID protocol that I implemented over the 14 days I had symptoms:
- Alkalizing with ACV/baking soda
- Iodine 12.5 mg
- Querticin 80mg with Bromelain 165mg
- Zinc 25 mg
- Vitamin C 3000- 10,000
- Melatonin 80 mg
- Multi-vitamin
- B-Complex
I am back on the Full COVID protocol. I had some NAC so I added that too.
I will take Turmeric this week to hopefully help with the diarrhea.
I will say the Melatonin and Art's insomnia protocol has helped me sleep better than I have in years with not as many bathroom trips during the night.
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https://www.docwirenews.com/abstracts/clinical-trial-to-test-the-efficacy-of-melatonin-in-covid-19/
Art
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Would you recommend melatonin for severe Copd and not inhaling H202? Thanks.
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I answered this question in the original reply I made to Nancy and there is further information re: COPD in my reply to Mama to Many.
Art
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https://devinenews.com/medina-county-woman-shares-what-her-battle-with-covid-was-like/
Art
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Excuse me for my terrible english, I realize now my question was not formulated clearly. Thank you again from the other side of the ocean!!!
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Yes, things definitely get lost in the translation sometimes!
I will have to look for the old study I mentioned, but they were using very bright light in that study which was far brighter than a computer monitor and that light could have been retina damaging on its own. I have been taking higher dose melatonin for over a decade and spend a lot of time on my computer and have not had a problem with my eyes, but I also take my melatonin at night except when I had Covid. In current studies, as I linked to previously, melatonin is retina protective, not degenerative or damaging.
Older studies hold some weight until they are proven incorrect by newer more comprehensive studies. If you have a newer study showing retinal damage, please link to it. I read melatonin studies everyday and have not seen this.
Art
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Paola
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Is the melatonin dose you recommend 1mg/kg or 1gm/kg? The latter seems much higher than most recommendations. Thank you.
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I was wondering if one of the side effects of melatonin would be lowered blood pressure. I once took melatonin a couple of hours after taking Tramadol and almost passed out a few times the following early morning. My blood pressure has always been on the low side which is normal for me.
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Thank you again!
Karen
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Thank you for inquiring. My last post was 10/29 so I will resume at that post to keep the info in some logical order.
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Thank you for a quick reply. And thank you for the suggestion of Valerian. I had taken it some time ago and will start again. I did get a weighted blanket, and after a "getting used to" period, I think it has helped some.
As far as the 2ne question about the supplements, I don't have any current issues to address. I just like to take supplements to maintain good health.
I usually take a multi-vitamin with minerals, extra D, extra C, and extra Zinc. I've added a few other supplements since I've had Covid - Iodine, lysine, Hemp Seed Oil, and MSM.
Are you permitted to recommend a Multi-vitamin brand that is good? There are so many to choose from.
So my 2nd question was, basicially, what Supplements are good to take to continue to maintain good health? Is there a post or a list of basic "good" stuff to take to maintain health?
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Generally I prefer to take supplements on an as needed basis. It sounds like you are taking some good supplements already, but a B vitamin multi such as B-50 might be a worthwhile addition to your current regimen.
Art
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First I would like to say thank you for coming back and updating on your use of melatonin for Covid-19 as this information is very useful for other members to help know what is useful!
Yes, I think you lessened your dose to soon. As for the diarrhea, Dr. Neel mentioned that in his more recent patients he was seeing gastrointestinal issues regularly and he felt it my be a different strain of Covid-19 than he had previously been seeing. You can try zinc at 50 mg/day for a short course to see if it is enough to regain normal digestion. Dr. Neel added antibiotics in some cases where he suspected bacterial infection.
You can also consider blackberries for the diarrhea.
If you have time, could you give us an idea of your experience with melatonin for Covid-19 and the dosing that you used throughout the treatment period? Thank you!
Art
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I will come back and fill in my usage of Melatonin for Covid, but for this post, would you elaborate on using blackberries? For example, try 1/4 cup once a day...
I will start Zinc tonight. Do you recommend 50 mg at once or divided morning and evening, or ....?
Melatonin
Here is a link to Ted from Bangkok's lysine anti-viral remedy. This link deals with H1N1, which is similar to the COVID-19 virus. The post also contains a list of other remedies against such viruses that also includes using Hydrogen Peroxide, MMS, Aspirin etc:
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I have just got over a median case of covid. I have copd and my breathing has worsened since, I just started taking or doing the hp protocol today. I have noticed in your article that melatonin fights off h2o2, so would it be advisable to say I should just do the melatonin to try to recover my lung capacity, I am not on any meds at this time.
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Melatonin
In the following 2020 article link below, it basically says that there is insufficient data to prove that melatonin is safe when pregnant and although there are tests being conducted for that purpose, that data is not yet available.
Another important point is that with Covid-19, it requires dosing that is magnitudes higher than what would be used for sleep. Bottom line is that there is no data for high dose melatonin in pregnancy, so melatonin is not a viable option for you.
https://womensmentalhealth.org/posts/update-2020-melatonin-pregnancy/
Art
Melatonin
Melatonin
★★★★★
Melatonin
Melatonin
Melatonin
Melatonin
Melatonin
Melatonin
Melatonin
Melatonin
Melatonin
Melatonin
Melatonin
Melatonin
Melatonin
Melatonin
