59 User Reviews
Melatonin
★★★★★
(Jordan)
05/11/2020
What brands of nanoparticle silver are good ones?
Ragaa Shabib, The only two products I have seen that appear to be AgNps or silver nanoparticles are MesoSilver and MediSilver : https://www.amazon.com/MediSILVER-AMBER-Traditional-Colloidal-Silver/dp/B00ADQ5VWS https://www.amazon.com/s?k=mesosilver&ref=nb_sb_noss_1 I'm not recommending either one, just saying they appear to be AgNPs. As far as I know, everything else is likely ionic silver as they are colorless unless you go to a chemical supplier who can probably get most anything you want, but probably at a higher price though. Art
I no sooner got this list above this post complete and posted last night and I read the following article that shows that Covid-19 is negatively affecting the eyes too! Just when I thought this disease couldn't get any worse, it does! https://www.medpagetoday.com/infectiousdisease/covid19/85752 Art
(California)
05/11/2020
What would it take to get this to politicians?
Dave, That is a really good question! I'm trying to spread the information around as much as possible about melatonin, but actually trying to get a politician to seriously look at and consider it is another story. What I have noticed is that the drugs that they are repurposing for use with Covid-19 patients are only marginally effective or not effective enough. Hydroxychloroquine is only marginally effective at best and Remdesivir, although touted by Fauci, is only marginally effective. This seems to be the case with most if not all of the drugs they are trying so far. It seems like more natural items like those presented here on EC are mostly ignored by scientists and the powers that be. The government is having to spend trillions of dollars to try and keep the economy going, but they don't seem interested in spending a few million dollars to trial supplements or vitamins of any kind. Our government seems so convoluted when it comes to Covid-19. Everyone seems to have their own agenda and alternatives, supplements, herbs and vitamins do not seem to be on anyone's agenda who might have the power to actually test them in patients. If I was in Fauci's or Trump's position, I would have a very small team of people scouring the internet everyday to find ideas that might sound promising and EC seems to be a very good place to start looking, but clearly that is not the case. They would rather pump their research dollars into drugs that are not really showing good results at all. Dr. Neel is, in one week, highly recommending that doctors use melatonin in their Covid-19 patients based on the very good safety profile of it, as well as a lot of research studies clearly suggesting that it is definitely worth trying and testing it. And then the very next week is already using it successfully in his patients. He's only been using it since the beginning of April and already has 14 patients on it. I think it is going to take doctors like him who are willing to suggest it to their patients. And if more doctors find similar results in their Covid-19 patients as Dr. Neel has, then the politicians will have no choice, but to start testing it in trials. In the meantime, we common folks are left to figure things out on our own! Art
(Africa)
05/11/2020
Art, If someone does not have access to melatonin, do you think drinking and nebulizing AgNP is a good alternative?
Dimoune, Before I found out about melatonin for this purpose, my intent was to use the combination approach of inhaling and drinking with silver nanoparticles (AgNPs). The truth is that there is no clinical experience with AgNPs for Covid-19 or anything else, but the method of action seems likely to work, so I would have tried it right away myself and if I didn't think it was working or working well enough, I would have moved on to something else or added something else with the AgNPs just in case. Art
Melatonin
(Madison)
05/08/2020
Trump is not pausing. It's about the economy... and of course his re-election. The re-opening is happening, whether we think it's a good idea or not. One of the things that amazes me is that so many of us refuse to social distance and wear masks. The masks are about caring for others, in case we are carrying the virus without knowing it. The social distancing is caring for ourselves and for others. Yes, it's a pain, but what is that compared to slowing the progression of the virus, compared to saving lives? My parents' generation went through the Great Depression and WW2. Neither of these difficult times lasted for a just few months, and they couldn't quit because they were 'tired of it'. C'mon folks! We can do this!
Hi Kathleen, Yes, apparently the economy is more important than human lives, but that is truly short sighted thinking as this virus has proven quite adept at spreading from human to human so once the economy opens again and people are back in relatively closed spaces together with many other people, the virus will begin its voracious spread again. Trump said the other day on the news that Covid-19 has been "some of his best work", but the stats for the US show that we are leading the world in number of cases at a whopping 33% of the total cases in the world! We are also leading the world in number of deaths with America accounting for 28% of the total deaths from Covid-19 in the world! All of that, yet we only account for 4.25% of the world population. We have more than 5 times the cases of the next closest country to us, Spain. We have greater than double the number of deaths than the next closest country, the UK! If this is some of Trump's best work......? Once the economy reopens, those numbers will climb much faster and put the US even further apart from the crowd.! I guess we really are expendable when it comes to money! On the other hand, if you are living from paycheck to paycheck and don't get back to work soon, you could lose everything you have and end up homeless or you can go back to work and possibly end up dead. It is a no win situation for many people! Art
Melatonin
★★★★★
Melatonin
★★★★★
Melatonin
Melatonin
★★★★★
Melatonin
You're welcome, Kristie! I hope you find it useful. Art
Melatonin
(Sri Lanka)
04/29/2020
Is is milligrams or micrograms?
Sithina, Dr. Neel is using about 80 milligrams total per day divided into four (4) 20 mg doses in his adult patients, but I believe he actually has a range of from 50 milligrams to 100 milligrams, depending on patient's size and severity of symptoms. The doctors Hospital in Manila has reported using a dose range of 36 to 72 milligrams/day in their patients. Both locations are giving that dose divided into four doses per day to achieve the daily dose Thank you for bringing up the dosing as I wouldn't want his protocol to be mistaken on something as critical as dosing! Art
Melatonin
★★★★★
Melatonin
★★★★★
Lavi, Do you mean is the melatonin addictive in terms of sleep, the answer for me is no. I have taken melatonin for years on and off with no problems when I have stopped, but now I take it everyday to avail myself of the many health benefits that melatonin may potentially offer. I am currently in the process of a longer term test of 80 mg/day to make sure it will be compatible. I already did a three day test and now I am testing it for a month to two months to assume a worst case scenario. So far no problems. Art
(Los Angeles)
05/24/2020
No Lavi, it doesn't make me dependent for sleep as I can only speak for myself.
Anne, Good to hear that melatonin is useful for you! I took another 80 mg dose last night to confirm that Dr. Neels dose of melatonin would not be a problem for me and it went similarly to the day before where I woke up a little earlier than usual and felt rested. I slept through the night on both nights of melatonin at 80 mg. Art
Melatonin
★★★★★
(United States)
05/01/2020
Hi Art, So would you suggest taking a smaller dosage as a preventative or just have it on hand in case we become ill?
Hi, Annette, Dr. Neel has not as yet suggested dosing until symptoms and a positive test are in place and then using his high dose melatonin protocol until well and at that point possibly shifting to a lower maintenance dose of possibly 5 milligrams/day. Thank you for your question! Art
Melatonin
★★★★★
(United States)
05/01/2020
I refuse to consume artificial man made melatonin which can cause headaches, sleep walking etc..., eat cherries or drink the juice for natural melatonin. There are also softgel cherries.
(California)
05/03/2020
T Hunter, You are correct that cherries contain melatonin and Montmorency cherries probably have the most melatonin in them, but they only contain miniscule amounts of melatonin. Here is some information on the melatonin content of cherries. Cherries, in particular the Montmorency variety, contain melatonin—about 13 nanograms of melatonin per gram of cherry. Recall that there are a million nanograms in a milligram, so a kilogram of cherries would contain 13,000 nanograms or 0.013 mg of melatonin. Based on the above paragraph, it would be impossible to get anywhere close to the amount of melatonin that Dr. Neel is suggesting. As mentioned above, 2.2 pounds of cherries would only contain 0.013 mg of melatonin. Dr. Neel is working with roughly 80 mg of melatonin/day or over 6,000 times as much as 2.2 pounds of cherries. It appears that sweet cherries have even less melatonin in them. On the other hand, most of the currently trialed drugs for Covid-19 have side effects that are likely significantly worse than melatonin. Art
(Tennessee)
05/04/2020
Herbatonin is food made melatonin. Ed Jones Nutrition.com
Hi, Rhonda! Unfortunately, yes, melatonin can have different effects in everyone. Are you certain it was the increased dosage that caused the headache? If it was, your doctor may be able to offer you something to relieve the headache if you end up using melatonin for Covid-19. It appears that the melatonin course can be fairly short if it is applied at or near the first symptom or symptoms with a Covid-19 test. This is when Dr. Neel is applying it to his Covid-19 patients with very good results to date. Even with the headache situation, melatonin has a better safety profile than every drug that is currently being tested for Covid-19, so it is still worth keeping in mind as a potential option! Thank you for your comment! Art
(United States)
04/29/2020
Art, I have had a slight heartache caused by the Corona virus.
David, If you have Covid-19 and heart pain, you need to see your doctor at once and let him know, because Covid-19 has shown the potential to damage the heart. Covid-19 is nothing to be taken lightly as it can damage the heart and can be fatal! This is a no nonsense disease that has shown that it can take lives as though they are nothing, even if you are young! Please let your doctor know what you are feeling right away! Art
Melatonin
★★★★★
Trina, You sound like a great mom still watching out for the "adult kids"! Dr. Neel has not yet suggested melatonin as a preventative. In fact he has only given it to patients who have tested positive for Covid-19. I don't think melatonin directly attacks the virus, but seems to manipulate the immune environment so as to give the body and the immune system a better situation to fight and destroy the virus itself, while ameliorating symptoms and preventing an over response by the immune system which can lead to a cytokine storm or pneumonia. On the outside chance that melatonin joins the growing list of "scarce supplements", it may be better to save the melatonin until it is actually needed to insure that you have enough melatonin at that time! Art
(Ghana)
05/09/2020
★★★★★
Art, Does that mean I shouldn't use melatonin since I am not infected? Because I have gotten one. Thanks.
Bern, When you say, 'I have gotten one', do you mean one bottle of melatonin? If that is the case, I don't know what strength the capsules or pills are or how many are in the bottle. Let's say that the bottle has 60 tablets or capsules and that each tablet is 10 milligrams. Dr. Neel is using 80 milligrams per day, so that means 8 capsules or tablets per day, so that means the bottle will only last 7 1/2 days. If the capsules or pills are 5 mg, then the bottle will only last 3 3/4 days. What I am doing for myself is making sure I have enough melatonin to last a month, so the bottles I bought are 10 mg and there are 60 capsules in the bottle. One bottle will last a week, so I bought 6 bottles for myself to make sure I am able to go about 6 weeks if needed. Remember, Dr. Neel has barely been using his HDM protocol for just about 6 weeks so he is himself still learning about dosing, but he mentioned that he has taken two of his patients down from 80 milligrams per day to 5 milligrams per day because they had improved very significantly. As far as when to start, Dr. Neel is starting his patients as soon as they show symptoms and test positive for Covid-19. He only has 14 patients so far and this is what he says he has done and seen very good results so far. In his patients who were showing significant symptoms, he said that they showed the beginning of improvement in one day, but he kept their dose at 80 mg/day. Art
Melatonin
★★★★★
Romina, You're welcome! I thought the very same thing, but I was previously able to do the same as the children's study that I linked to in the post which was 70 mg / day for 90 days to children with Duchenne Muscular Dystrophy. They showed good effects in that study and since I experiment on myself a lot, I decided to try it so I would know. Yes, I did have the melatonin hangover for about two to three weeks, but it slowly went away over time. The good thing is the high dosing that Dr. Neel is using is only temporary and that is probably a good time to rest anyway and if the treatment significantly reduces symptoms, I'll gladly take his dosing rate over the more symptoms! As far as I can tell about the high altitude sickness idea, the idea is interesting or maybe a better word would be intriguing, but I think it is unproven and as related to Dr. Neel's melatonin protocol, it doesn't seem to matter either way as melatonin seems to help the body recover on its own and fight the virus with the assistance of melatonin. This could help to achieve 'herd immunity" and offer help in the future should the virus mutate extensively and is not sensitive to the antibodies created. I want to consider this scenario in case the virus returns each year like the cold and the flu. If Dr. Neel is correct, melatonin may be the way to move forward in a relatively safe manner, especially if the economy is opened soon. Thank you for your reply! Art
Melatonin
(Essex, England)
04/23/2020
Hi Jan, What is the name of this product you have please and is available in England?
Jan, Those are good ingredients in the list, but you may want to check with your doctor to make sure that they are all compatible with whatever prescriptions you may be taking, just to be safe! Be sure to specifically ask your doctor about melatonin if you do plan to take it at some point! Here is a link to known side effects of melatonin and this list may not be complete as people don't always report every single side effect they may have: https://www.mayoclinic.org/healthy-lifestyle/adult-health/expert-answers/melatonin-side-effects/faq-20057874 Art
Melatonin
★★★★★
Deborah, Zinc is proving to be quite popular as it is thought to disrupt the viral replication process and having sufficient zinc in your system without overdosing makes good sense! I ordered zinc picolinate because it has shown in at least one study to be more effective than other forms of zinc supplements in terms of bioavailability. That order took close to a month to arrive, so clearly plenty of interest in zinc! Earth Clinic belongs to Deirdre Layne and I am just posting information like other people on EC! I really like EC and reference it often! I will pass your thank you along to Deirdre and EC! Art
Melatonin
Melatonin
★★★★☆
(usa)
04/21/2020
Dr. Brownstein has been giving his patients natural medicines such as iodine, vitamin C, zinc, and other protocols, and none of his patients needed a ventilator. He's got videos on YouTube. Some of his patients are even testifying about their experiences.
(Ohio)
04/30/2020
★★★★☆
Art, Thank you for the great info! I have been following Dr. Klinghardt on YouTube. I think that you (and everyone else here) would greatly appreciate the wealth of information he is sharing. Stay well! Lisa
Hi Deborah,
Yes, it appears that those supplements and combinations can be very helpful judging by the comments on them across the internet.
Vitamin C seems to be most effective through IV, which can be hard to get and is pricey. Liposomal C can be similarly effective as IV vitamin C, but it too is pricey.
Zinc can be helpful also, but zinc needs an assisting ionophore such as Hydroxychloroquine or quercetin at high dose in order to help get enough zinc into the infected cells and disrupt the viral replication process.
Covid-19 has those spike proteins and these attach or dock to a specific cell receptor and once they dock, they inject RNA into the cell and hijack the cell to turn the cell into a virus making factory until the cell dies and all of the viral particles inside are released and move on to other cells to infect in the same way as the first viral particle did. When enough zinc can enter the cell with the aid of an ionophore, then the zinc can disrupt the viral replication process effectively. Zinc on its own seems to have limited access to the cells. The ionophore assists with cell entry by zinc.
Iodine has already been discussed extensively on EC.
There are a some specific things about melatonin that make it practical for this purpose.
1. It is relatively inexpensive and although a limited number of cases, Dr. Neel has seen improvement in just one day in his patients so it is fast acting and it alleviates the symptoms making it easier to tolerate the disease while it is active in your system.
2. It has shown that it is effective along side Hydroxychloroquine, and based on the available studies, it has shown synergy with other supplements such as the quercetin + melatonin study in the original post for this thread.
3. Melatonin has a very good safety profile as it should considering the the pineal gland produces it and excretes it every night.
4. Melatonin level peaks around the age of 5 years and the level declines very sharply from puberty on and is very low by the late fifties and beyond, the same age as those who are at highest risk for succumbing to Covid-19, as the chart inside the initial post clearly illustrates.
5. Melatonin is easy to obtain in the US. I don't know if you have shopped for the items on your list lately, but they are simply hard to come by right now, while melatonin is still available the last time I checked.
6. Melatonin actually attenuates part of the immune response so as to greatly reduce the chances for a cytokine storm and allows the immune system enough time to create antibodies to fight the virus the way it should and all the while making more antibodies to destroy the virus.
Dr Neel is essentially just using melatonin with oral vitamin C, but the hospital in the Philippines is using melatonin by itself and melatonin + Tocilizumab / Actemra which is a specific IL-6 inhibitor that is sometimes used for arthritis and cytokine storms. The doctor who commented on it said that Actrema and melatonin seem to do the same things.
7. Melatonin appears to be effective on its own which makes it an inexpensive and very simple treatment with a good safety profile while significantly ameliorating C-19 symptoms while further allowing the immune system to do the job it was meant to do!
8. Melatonin in hundreds of studies has shown its ability to protect the major organs of the body and with the latest available information from patient autopsies, C-19 is showing that it is also attacking the kidneys, liver, heart, lungs and possibly the brain because viral particles have been found in the brain.
9. In reality, most of the possible drugs are still being trialed which means they are not available to the masses until one of the trials proves that that particular drug is effective enough and then the FDA will have to review the trial and approve the drug for off label use and all that means that it will be a bit of time until one of those drugs is ready for use by the public for Covid-19. Given the worldwide demand for such a drug, there may simply not be enough available to meet demand, even with a ramped up production plan.
Bottom line, will there be enough to go around?
This sounds like a pretty good case for melatonin, at least to me it does.
Given all of the above, it certainly seems worthwhile to have a conversation with your doctor about melatonin before you actually need to take it.
Art
Well, you can't argue with what worked for you in 6 weeks, Tom! Thank you for the ACV report! The only difference is that Dr. Neel is suggesting that his patients are already seeing improvement after a day of melatonin at high dose. The patient in the Philippine hospital with Covid-19 pneumonia who was about to be put on a ventilator improved significantly after just 3 days of high dose melatonin and they didn't have to put him on a ventilator and then was released 9 days later! The other possible benefit is that none of his patients ended up worsening to pneumonia after Dr. Neel started them on high dose melatonin! Art
Melatonin
Deirdre, Dr. Neel has finally mentioned a maintenance dose, but it is for patients who are already recovering, not as a prophylactic because he has mentioned that Melatonin does not directly kill the virus. So basically he has been starting his adult patients around 80 mg total per day and then once they are well improved he will consider having them go down to a maintenance dose in the lower range around 5 mg/day, but he is the one making that call, not the patient and this is likely a very important part since you may feel much better before you are completely well! Art
(California)
04/21/2020
Thank you, Deirdre! Dr. Neel has not mentioned any type of maintenance dose so far and I suspect he won't because the one patient where he tried to reduce her dose from 80 mg/day down to 40 mg/day resulted in the patient developing a cough which went away when he increased her dose back to 80 mg. I think this is what he is finding to be an effective dose for adults and so far has not suggested any type of maintenance dose. Melatonin can not stop you from getting Covid-19, but what Dr. Neel is finding is that it can help keep the virus from instigating the cytokine storm which has resulted in the deaths of patients around the world. He also finds that patients are responding positively to melatonin in just one day! A maintenance dose is not likely required since it is the higher dose that he is using in his patients that is actually making the difference. On a very related note, if melatonin becomes scarce as other supplements like vitamins A, C, D and zinc have become, it may make more sense to save the melatonin that you have until it is actually needed. Thank you again! Art
Melatonin
(Santa Cruz)
04/21/2020
★★★★☆
Jane. Yes. About 20 years ago when I took it and I felt like I was on an acid trip all night long. I tried it again (I'm in my 70s) and it only makes me dream a little wildly. I can feel after taking it what it does to my brain. I am a meditator so I think I'm just a little sensitive. Sometimes it works and sometimes it doesn't.
Rami, Hopefully your tolerance of melatonin is good enough so that you can keep it in mind should it ever be needed and hopefully, you won't ever need it! Art
Jane, That is a rare side effect of melatonin. For myself, I would have to weigh the potential benefit of using melatonin for Covid-19 against the side effect. In a hospital setting would be the best situation because then the doctor and nurses would be able to monitor you and keep you safe! As I mentioned in the post, some people can not tolerate melatonin, but the majority of people can. If the hallucinations are significant, your doctor may not want you to use melatonin. Art
Melatonin
★★★★★
Thank you, Ed! I'm listening to your podcast as I type! Interesting. I am at the melatonin discussion right now! Dr. Neel seems to be having very good results in his Covid-19 patients using melatonin at 80 mg/day divided into four doses, but I am waiting for the hospital in the Philippines to announce who is going to publish their science paper discussing what they saw in their Covid-19 patients. They seem to be having similar success to Dr. Neel in their melatonin/Covid-19 patients! Thank you for the links! Art
Melatonin
★★★★★
(Los Angeles)
04/21/2020
Thanks, Art. I will take the melatonin a bit earlier. But what about the combination of the Quercetin you mentioned. Is that necessary with the both together?
Sorry, I forgot to answer that. I added that study into the post for the specific reason that quercetin and zinc are one of the popular combinations being suggested as a possible treatment for Covid-19, but it is unproven and untested yet. I just wanted to show that melatonin can be compatible and possibly synergistic with other supplements such as quercetin! Art
Deborah, You can try using a nationally known brand like the ones that Amazon carries and then that way it will be delivered to your door without you having to go to the store and this way you can lessen any possible exposure to Covid-19. I agree about the "melatonin hangover" that you mention because I have gotten it before, but it gets less noticeable the longer I use melatonin. It makes me feel lazy and I don't want to get out of bed. For myself, I take it a little earlier in the evening and that seems to help me. It is worth mentioning that the dosing that Dr. Neel is using in his Covid-19 patients is a relatively high dose and he is only using that dose as long as the patient is testing positive, so he is giving a high dose for a relatively short period of time. Thank you for your comment! Art
